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No Slide Title
No Slide Title

... Usually repeated structures Examples: a helix, b sheets, random coil, or b turns ...
Problem Set 1A
Problem Set 1A

... group, label the 5’ and 3’ carbon positions with numbers, and show the hydrogen bonding between paired bases with dashed lines (even though they don’t need to be placed accurately with respect to specific atoms). Label the 5’ and 3’ ends of each strand. The only nitrogen atoms you need to show are t ...
A modified acidic approach for DNA extraction from
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Ch.16 17 Study Guide
Ch.16 17 Study Guide

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Worksheet 2 - Cloudfront.net

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Transcript - University of Idaho

... acids. The genetic code is said to be universal since it applies to ALL organisms. Note that most amino acids are encoded by more than one codon. However, every codon always encodes for only one amino acid; thus the genetic code is unambiguous. The first two letters for the codons of a particular am ...
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CHAPTER 12

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Notes - The University of Sydney
Notes - The University of Sydney

... base or acid. These solutions buffer best ± 1 pH unit either side of their pKa. The ratio of the acid and its conjugate base (or base and its conjugate acid) will determine the pH within this range. To work out the ratio of acid to base you employ the Henderson Hasselbalch equation (this equation us ...
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Amino Acid Biosynthesis Student Companion Ch 24 Self Test

... 10) The branchpoint for aromatic amino acid biosynthesis is chorismate. What is the structure of chorismate? What are the three immediate products derived from chorismate that constitute the first unique steps in the synthesis of the three aromatic amino acids? 11) From where are the two carbons of ...
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385 Genetic Transformation : a Retrospective Appreciation

... pathways, the mutation in the recipient being indicated by the cross, while the ‘ B’ region is concerned with capsular specificity. Note that in transformation, as in other forms of bacterial sexuality, the fragmentary nature of the genetic contribution of the donor demands at least two genetic exch ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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