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basic genetics for the clinical neurologist
basic genetics for the clinical neurologist

... bacteriophage, finally proved that DNA and not the more complex protein was the hereditary material. DNA is made of two anti-parallel helical polynucleotide chains wrapped around each other and held together with hydrogen bonds to form a double helix. The backbone of the helices are made from altern ...
THE GENE THE EVIDENCE OF THE NUCLEOPROTEIN NATURE OF
THE GENE THE EVIDENCE OF THE NUCLEOPROTEIN NATURE OF

... to reconcile the so-called uniformity of the nucleic acids with their possible presence in the genes in another way, which we will come to presently. It is well, however, first to question the extent of the uniformity. Nucleic acids have been found to fall into two groups, according to the sugar the ...
Translation - Fog.ccsf.edu
Translation - Fog.ccsf.edu

... free amino group of incoming amino acid Proteins are synthesized from its Nterminus to its C-terminus ...
DNA and Cell Division
DNA and Cell Division

... The mRNA is directly involved in the protein-making process. mRNA tells the ribosome (Figure below) how to create a protein. The process of reading the mRNA code in the ribosome to make a protein is called translation (Figure below). Sets of three bases, called codons, are read in the ribosome; the ...
Genetic engineering
Genetic engineering

... Before Dolly, the majority view was that such differentiated cells could not be reprogrammed to be able to behave as fertilised eggs. Dolly was produced by a process known as "adult DNA cloning", which produces a duplicate of an existing animal. The technique is also known as "cell nuclear replaceme ...
Gene Mutations - WordPress.com
Gene Mutations - WordPress.com



... Choice B: A number of amino acids are associated with more than one codon. For example, the amino acid Phe can be incorporated into a peptide chain whether the codon is UUU or UUC, yet there is only one tRNA molecule that is charged with Phe. Briefly explain how this occurs. ...
The Action of Chloramphenicol on Protein and Nucleic Acid
The Action of Chloramphenicol on Protein and Nucleic Acid

... IP: 88.99.165.207 On: Sun, 18 Jun 2017 04:24:04 ...
cell cycle
cell cycle

... 2. Construct a bar graph that displays the relative amounts of hydrogen, carbon, oxygen, and nitrogen in each of the four types of macromolecules (carbohydrates, lipids, proteins, nucleic acids). ...
The nucleotide sequence of the tnpA gene completes the sequence
The nucleotide sequence of the tnpA gene completes the sequence

... a reading frame that is not present in Tn501 (41). The reading frames urf-1 and urf-2 have not been ascribed a function. The exact positions of gene boundaries and other features are given in Table 1, as are references to the sequence data. The transposon is 8355 nucleotide pairs in length. ...
The Action of Chloramphenicol on Protein and Nucleic Acid
The Action of Chloramphenicol on Protein and Nucleic Acid

... IP: 88.99.165.207 On: Sat, 17 Jun 2017 12:31:39 ...
Ab_initio_predition_tools - Compgenomics2010
Ab_initio_predition_tools - Compgenomics2010

... of RBS score ,IMM coding potentials and a score for start codons which is dependent on relative frequency of each possible start codon in the same training set used for RBS determination. • Algorithm used reverse scoring of IMM by scoring all ORF (open reading frames) in reverse ,from the stop codon ...
Organic Chemistry #2 Vocabulary Adhesion Cohesion Atom
Organic Chemistry #2 Vocabulary Adhesion Cohesion Atom

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Basic Biology - NIU Department of Biological Sciences
Basic Biology - NIU Department of Biological Sciences

... phosphate, and a base. The sugar, ribose in RNA and deoxyribose in DNA, contain 5 carbons. They differ only in that an –OH group in ribose is replaced by a –H in DNA. The main energy-carrying molecule in the cell is ATP. ATP is an RNA nucleotide with 3 phosphate groups attached to it in a chain. The ...
Brief Answer Key (up to 2/9)
Brief Answer Key (up to 2/9)

... nitrogenous base of another nucleotide 6.) What two interactions are occurring in the DNA double helix? Explain each. Together, both yield what structural benefit for the helix? a. Complementary base pairing and Base stacking by hydrophobic interactions b. Provides stability 7.) The directionality o ...
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... proteins that form a heterodimer complex. The amino acid sequence of the catalytic region of yeast RTPase subunit has no obvious similarity to PTPs [9,10]. Unlike metazoan RTPases, the yeast proteins require divalent cations for activity [11,12]. It has been suggested that fungal RTPases comprise a ...
14–3 Human Molecular Genetics
14–3 Human Molecular Genetics

... The results of the Human Genome Project have led to the possibility of using gene therapy to treat genetic disorders. Gene therapy involves replacing a defective or missing gene in a person’s genome. ...
Slide 1
Slide 1

... • Cell – The smallest structural and functional unit of an organism; DNA is located in cells. • Chromosomes – Structures that contain compacted DNA molecules; humans have 46 chromosomes and every species has it own unique number. • Double helix – The physical “twisted ladder” structure of DNA. • DNA ...
DNA – The Molecule of Life
DNA – The Molecule of Life

... which separated the heavier bacterial cells in the pellet from lighter free phages and parts of phage in the liquid supernatant. They then tested the pellet and supernatant of the separate treatments for the presence of radioactivity. ...
Review sheet – Chapter 3 Understand that organic compounds are
Review sheet – Chapter 3 Understand that organic compounds are

... Be able to recognize estrogen, cortisol, progesterone and cholesterol as steroids Understand that proteins are built up from 20 different amino acids Know that amino acids are molecules that have a carboxyl and amino group Be able to identify an example of a protein or a substance made up of protein ...
Fat Soluble Vitamins
Fat Soluble Vitamins

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Ch. 8: Presentation Slides

... donor cell to a recipient cell by cell-to-cell contact • The transfer is mediated by a tube-like structure called a pilus, formed between the cells, through which the plasmid DNA passes • The ~20 proteins that make up the pilus are encoded by the Ffactor plasmid ...
Bio/CS 251 Bioinformatics Homework 4 20 points
Bio/CS 251 Bioinformatics Homework 4 20 points

... The peptidyl site would be occupied by a peptidyl-tRNA that carries the MET-GLU-ILE tripeptide, and the aminoacyl site would contain the next aa-tRNA to be added to the growing peptide. In this case the aminoacyl site would contain the UGG codon to pair with the anticodon of Trp-tRNA. ...
Properties of the Genetic Code under Directional, Asymmetric
Properties of the Genetic Code under Directional, Asymmetric

Nutrients that Support Phase II Detoxification
Nutrients that Support Phase II Detoxification

... intermediates are conjugated and altered further before expulsion from the body. Six different major biochemical reactions occur in this phase, known as: Glutathione conjugation Amino acid conjugation Methylation Sulfation Acetylation Glucuronidation Each of these reactions works on specific types o ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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