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Word of the Day
Word of the Day

... From DNA to You Proteins are made from chains of amino acids, the order of these AA’s determines the structure of a protein. The genetic code is a way of reading the sequence of amino acids. A codon is a combination of three nitrogen containing bases in a row. Each codon codes for a different amino- ...
wanted - Copenhagen Plant Science Centre
wanted - Copenhagen Plant Science Centre

... DNA that does not code for proteins (non-coding DNA) makes up the vast majority of bases in many genomes yet we understand little about its role. Non-coding regions are actively transcribed by the same complex transcribing genes (RNA polymerase II, Pol II). Transcription of non-coding sequences resu ...
Protein Synthesis Digital Guide
Protein Synthesis Digital Guide

... • Identify the nitrogen bases that form RNA nucleotides • List three differences between RNA and DNA • Differentiate between the three main types of RNA and their functions • Explain what comprises the central dogma • Identify the location in an eukaryotic cell where the processes of replicatio ...
Eukaryotic Gene Regulation
Eukaryotic Gene Regulation

... Turning On and Off Genes (Gene Regulation) in Eukaryotes  Conserves energy that the cell needs for other ...
Chapter 10 - Power Point Presentation
Chapter 10 - Power Point Presentation

... before making the protein. The portions that remain and ARE used are called exons So, eukaryotes undergo RNA splicing This is one way a gene can have some variability in its outcome ...
How many nucleotides are in 12 mRNA codons?
How many nucleotides are in 12 mRNA codons?

... The first amino acid will be wrong, but the last three will be correct. ...
LKCMedicine Lecture Series by Asst Prof Chng Toh Hean
LKCMedicine Lecture Series by Asst Prof Chng Toh Hean

... transcription of new genes and synthesis of new proteins. The transport of synaptically-localised transcriptional regulators during neuronal activity provides a method of coupling synaptic activation with changes in the transcription. Asst Prof Chng’s lab is interested in studying the molecular basi ...
Postdoc Opening
Postdoc Opening

... genome-scale regulation in bacteria. Current goals include understanding how transcriptional regulators alter RNA polymerase conformation to control RNA synthesis (Nayak et al., 2013; Hein et al., 2014; Project 1) and how nucleoprotein filaments formed on bacterial chromosomes and transcriptional pa ...
PROTEIN SYNTHESIS and CONSTRUCTION SITE ANALOGY
PROTEIN SYNTHESIS and CONSTRUCTION SITE ANALOGY

... Transcription takes place in the nucleus, where Genes (DNA) on Chromosomes are transcribed into mRNA by RNA Polymerase. Translation takes place within City Limits. Blueprints dictate the types and order of transport trucks that deliver building blocks to the construction machine. Each transport truc ...
Control of Gene Express in Prokaryotes
Control of Gene Express in Prokaryotes

... • Different cell types make different proteins • role of transcription regulation • two sources of cellular instructions for determination: cytoplasmic determinants and neighboring cells ...
DNA to RNA
DNA to RNA

... information you need—shorter/simpler Think of it like this: DNA = master copy RNA = blueprints…you don’t need the blueprints for the whole house to build the foundation ...
Lecture#5 - Introduction to gene regulation and operons in
Lecture#5 - Introduction to gene regulation and operons in

... First understanding of gene regulation comes from the work of Jacob and Monod in the 1950's and ‘60's -> Nobel prize in 1965. Inducers - specific substrates that induced the appearance of specific enzymes (new synthesis of the enzymes). beta-galactosidase could be induced with several types of beta- ...
Computer science
Computer science

... • Analysis of protein-DNA interactions: breaking the cis-regulatory code. “ Regulatory interactions mandated by circuitry encoded in the genome determine whether each gene is expressed in each cell, throughout developmental space and time, and, if so, at what amplitude.” Eric Davidson • Analysis of ...
Gene Expression - Biology Department | Western Washington
Gene Expression - Biology Department | Western Washington

... UTRs are transcribed, but not translated. UTR sequences diverge more rapidly during evolution ...
October 3, 2016 Worksheet
October 3, 2016 Worksheet

... Do we use introns or exons? Draw a strand of DNA that contains silencer, repressor, basal transcription factors, TATA box, (transcription factors): https://www.youtube.com/watch?v=ysxtZJUeTCE Why does these processes need to happen? ...
Features of the genetic code
Features of the genetic code

... • Mutations that modify the genetic code are of 3 types: frameshift (include deletions and insertions), missense (lead to an amino acid replacement) and nonsense (mutation that generates any of the three stop codons leading a a premature truncation of the polypeptide. ...
RNA Transcription
RNA Transcription

... once 'information' has passed into protein it cannot get out again. The transfer of information from nucleic acid to nucleic acid, or from nucleic acid to protein, may be possible, but transfer from protein to protein, or from protein to nucleic acid, is ...
How do we get proteins? - Sebastian Charter Junior High
How do we get proteins? - Sebastian Charter Junior High

...  DNA is used to make a single strand of RNA that is ...
ppt link
ppt link

... Antibiotics such as Rifampicin / rifamycin B inhibit RNA polymerase activity ...
Outline 2 Part 1
Outline 2 Part 1

... b. We’ll talk about what’s really true as time goes by… ...
CHAPTER 12
CHAPTER 12

... • HLH-containing transcription factors play a key role in the differentiation of certain tissues. • HLH-containing transcription factors also participate in the control of cell proliferation and cancer. ...
Chapter 16 Gene Regulation Levels of Gene Regulation Bacterial
Chapter 16 Gene Regulation Levels of Gene Regulation Bacterial

... • Multicellular specialization – Genes for one cell type are not expressed in other cell types ...
Regulation
Regulation

... Adaptive – Ability to initiate Transcription –Control by signal Proteins Environmental Signals facilitate Transcription Positive Regulation Environmental Signals interfere with Transcription Negative Regulation ...
Document
Document

... having evolved one from another through gene duplication. Paralogs are separated by a gene duplication event. • Each specific gene family member (e.g. a specific gene in human) is an ortholog of the same family member in another species (e.g. mouse). Both evolved from an ancestral globin gene. Ortho ...
Cellular Control miniQUIZ
Cellular Control miniQUIZ

... Using the diagram above answer the following questions: a) Which segment of the fruit fly develops wings? b) Are plant homeobox genes homologous to the homeobox genes in the fruit fly? 17. Apoptosis is important during development. Define the meaning of apoptosis and give an example. ...
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Transcriptional regulation

In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. This control allows the cell or organism to respond to a variety of intra- and extracellular signals and thus mount a response. Some examples of this include producing the mRNA that encode enzymes to adapt to a change in a food source, producing the gene products involved in cell cycle specific activities, and producing the gene products responsible for cellular differentiation in higher eukaryotes.The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working in concert to finely tune the amount of RNA being produced through a variety of mechanisms. Prokaryotic organisms and eukaryotic organisms have very different strategies of accomplishing control over transcription, but some important features remain conserved between the two. Most importantly is the idea of combinatorial control, which is that any given gene is likely controlled by a specific combination of factors to control transcription. In a hypothetical example, the factors A and B might regulate a distinct set of genes from the combination of factors A and C. This combinatorial nature extends to complexes of far more than two proteins, and allows a very small subset (less than 10%) of the genome to control the transcriptional program of the entire cell.
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