April 3 lecture slides
... Structures like this involving DNA with bound activator proteins and RNA polymerase complex are names “enhanceosomes”. TBP stands for TATAbinding protein, a component of RNA polymerase II associated factor, TFIID ...
... Structures like this involving DNA with bound activator proteins and RNA polymerase complex are names “enhanceosomes”. TBP stands for TATAbinding protein, a component of RNA polymerase II associated factor, TFIID ...
Molecular genetics of gene expression
... Transcription factors: proteins that bind to promoters to affect transcription • Transcriptional activators- Recruits the RNA polymerase complex to the transcription start site by binding to either sequences in the promoter or distant cis-acting elements to increase transcription. • Transcriptional ...
... Transcription factors: proteins that bind to promoters to affect transcription • Transcriptional activators- Recruits the RNA polymerase complex to the transcription start site by binding to either sequences in the promoter or distant cis-acting elements to increase transcription. • Transcriptional ...
04/01
... 1. Minisatellite DNA These are 1 to 5 kb in length consisting of repeats 15 to 100 nucleotides in length and are identified ...
... 1. Minisatellite DNA These are 1 to 5 kb in length consisting of repeats 15 to 100 nucleotides in length and are identified ...
Steps in gene expression: comparison of
... separated from protein, denatured to separate the strands, and electrophoresed. The resulting gel is analyzed by autoradiography, which detects only labeled strands and reveals fragments extending from the labeled end to the site of cleavage by DNase I. ...
... separated from protein, denatured to separate the strands, and electrophoresed. The resulting gel is analyzed by autoradiography, which detects only labeled strands and reveals fragments extending from the labeled end to the site of cleavage by DNase I. ...
CHAPTER 19 -- EUKARYOTIC GENE EXPRESSION YOU MUST
... Some of these mutations can be spontaneous, but mostly caused by environmental factors (mutagens) or viruses. Viruses can transfer the healthy genes to cancer causing genes by inserting their DNA into the host cell’s DNA at the gene segment. The normal version of the genes that are responsible f ...
... Some of these mutations can be spontaneous, but mostly caused by environmental factors (mutagens) or viruses. Viruses can transfer the healthy genes to cancer causing genes by inserting their DNA into the host cell’s DNA at the gene segment. The normal version of the genes that are responsible f ...
Lecture #7 Date ______
... of RNA begins Terminator region: sequence that signals the end of transcription Transcription unit: stretch of DNA transcribed into an RNA molecule ...
... of RNA begins Terminator region: sequence that signals the end of transcription Transcription unit: stretch of DNA transcribed into an RNA molecule ...
Lecture Notes
... activated in response to a sudden increase in environment – temperature -> heat shock proteins – toxic heavy metals -> metal response elements ...
... activated in response to a sudden increase in environment – temperature -> heat shock proteins – toxic heavy metals -> metal response elements ...
6.4 Gene Regulation - Ms. Franklin`s Classroom
... active repressor. If there is no lactose in the environment transcription of the enzymes must be repressed. The active repressor binds to the operator and presents the RNA polymerase from moving forward. ...
... active repressor. If there is no lactose in the environment transcription of the enzymes must be repressed. The active repressor binds to the operator and presents the RNA polymerase from moving forward. ...
Slide 1
... four proteins (see Figures 7-52 and 7-53). The expression of eve in stripe 2 occurs only at the position where the two activators (Bicoid and Hunchback) are present and the two repressors (Giant and Krüppel) are absent. In fly embryos that lack Krüppel, for example, stripe 2 expands posteriorly. Lik ...
... four proteins (see Figures 7-52 and 7-53). The expression of eve in stripe 2 occurs only at the position where the two activators (Bicoid and Hunchback) are present and the two repressors (Giant and Krüppel) are absent. In fly embryos that lack Krüppel, for example, stripe 2 expands posteriorly. Lik ...
Eukaryotic Gene Regulation
... Distal control elements (farther away) – enhancers Causes DNA to bend so transcription factors (activators) bound to enhancers can contact proteins of TIC of promoter Repressors bind to control elements known as silencers (much less common) ...
... Distal control elements (farther away) – enhancers Causes DNA to bend so transcription factors (activators) bound to enhancers can contact proteins of TIC of promoter Repressors bind to control elements known as silencers (much less common) ...
Proteins
... pries DNA apart and hooks RNA nucleotides together from the DNA code Promoter region on DNA: where RNA polymerase attaches and where initiation of RNA begins ...
... pries DNA apart and hooks RNA nucleotides together from the DNA code Promoter region on DNA: where RNA polymerase attaches and where initiation of RNA begins ...
Gene Control
... the activator transcription factors to slow transcription i. by binding to distal control elements and keeping activators out ii. By binding to activator proteins ...
... the activator transcription factors to slow transcription i. by binding to distal control elements and keeping activators out ii. By binding to activator proteins ...
UNIT 6 lecture part 3regulation
... REGULATORY PROTEINS: Besides the promoter, other DNA sequences can bind regulatory proteins that interact with RNA polymerase and regulate transcription. Some are positive regulators—activators (DNA sequence is called an enhancer); others are negative—repressors (DNA sequence is called a silencer ...
... REGULATORY PROTEINS: Besides the promoter, other DNA sequences can bind regulatory proteins that interact with RNA polymerase and regulate transcription. Some are positive regulators—activators (DNA sequence is called an enhancer); others are negative—repressors (DNA sequence is called a silencer ...
transcription
... Molecular circuits ------------------------------House keeping genes; constitutive gene expression ...
... Molecular circuits ------------------------------House keeping genes; constitutive gene expression ...
Eukaryotic Transcription In all species, transcription begins with the
... in eukaryotes. The breakthrough came in 1996 when a number of research groups discovered that certain transcriptional coactivators are histone acetyltransferases (HATs). It has been known for some time that binding of transcriptional activators to the enhancer region, in most cases, is not sufficien ...
... in eukaryotes. The breakthrough came in 1996 when a number of research groups discovered that certain transcriptional coactivators are histone acetyltransferases (HATs). It has been known for some time that binding of transcriptional activators to the enhancer region, in most cases, is not sufficien ...
Biology Ch 10 How Proteins are Made
... • The genes don’t directly make proteins – A combined effort between 3 types of RNA ...
... • The genes don’t directly make proteins – A combined effort between 3 types of RNA ...
3. Activator, gene-specific transcription facotr
... • Changes in the activity of pre-existing proteins • Changes in the amounts of protein via gene transcription ...
... • Changes in the activity of pre-existing proteins • Changes in the amounts of protein via gene transcription ...
Brooker Chapter 15
... In plants and animals, multicellularity and a more complex cell structure, also demand a much greater level of gene expression Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
... In plants and animals, multicellularity and a more complex cell structure, also demand a much greater level of gene expression Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
Allosteric Modulation of DNA by Small Molecules
... and Environmental Research, with additional support from the National Institutes of Health, National Center for Research Resources, Biomedical Technology Program, and the National Institute of General Medical Sciences. ...
... and Environmental Research, with additional support from the National Institutes of Health, National Center for Research Resources, Biomedical Technology Program, and the National Institute of General Medical Sciences. ...
Gene to Protein
... DNA – forms Hydrogen bonds and reforms double helix mRNA is edited (remove introns, exons are to be expressed) mRNA leaves the nucleus and enters cytoplasm for translation ...
... DNA – forms Hydrogen bonds and reforms double helix mRNA is edited (remove introns, exons are to be expressed) mRNA leaves the nucleus and enters cytoplasm for translation ...