Organic Chemistry II Introduction
... Alcohols and Phenols • Important solvents and intermediates • Phenols contain an OH group connected to a carbon in a benzene ...
... Alcohols and Phenols • Important solvents and intermediates • Phenols contain an OH group connected to a carbon in a benzene ...
Thermodynamics and kinetics of the hydrolysis of atmospherically
... thermodynamic parameters obtained for the difunctional primary or secondary butyl organosulfate systems in the present work are reported in Table 2. Since 1Ghyd is negative for all systems at standard state, it is clear that the alcohol species are thermodynamically favored over the organosulfate sp ...
... thermodynamic parameters obtained for the difunctional primary or secondary butyl organosulfate systems in the present work are reported in Table 2. Since 1Ghyd is negative for all systems at standard state, it is clear that the alcohol species are thermodynamically favored over the organosulfate sp ...
Relevance of the Physicochemical Properties of Calcined Quail
... The basicity of the catalyst was studied by temperatureprogrammed desorption of CO2 . Approximately 100 mg of sample was pretreated with a stream of helium at 800∘ C for 30 min (10∘ C min−1 and 60 mL min−1 ). The reaction temperature was then decreased to 100∘ C, and a flow of pure CO2 (60 mL min−1 ...
... The basicity of the catalyst was studied by temperatureprogrammed desorption of CO2 . Approximately 100 mg of sample was pretreated with a stream of helium at 800∘ C for 30 min (10∘ C min−1 and 60 mL min−1 ). The reaction temperature was then decreased to 100∘ C, and a flow of pure CO2 (60 mL min−1 ...
Microsoft Word
... Enantioselective Synthesis of Tamiflu In this chapter a brief account of the synthesis of tamiflu by selected research groups is described followed by and an elaborate account of the present work. Oseltamivir phosphate (Tamiflu) 85, is an approved orally effective neuraminidase inhibitor used for th ...
... Enantioselective Synthesis of Tamiflu In this chapter a brief account of the synthesis of tamiflu by selected research groups is described followed by and an elaborate account of the present work. Oseltamivir phosphate (Tamiflu) 85, is an approved orally effective neuraminidase inhibitor used for th ...
Determination of Equilibrium Constants for the
... density functional theory, they predicted formation of hydrogenbonded complexes between HO2 and formaldehyde, acetaldehyde, and acetone, with binding energies for the resulting HO2(R2CO) complexes of D0 = 26, 33, and 37 kJ mol1, respectively, at the B3LYP/6-311++G(3df,3pd) level. These complexes ar ...
... density functional theory, they predicted formation of hydrogenbonded complexes between HO2 and formaldehyde, acetaldehyde, and acetone, with binding energies for the resulting HO2(R2CO) complexes of D0 = 26, 33, and 37 kJ mol1, respectively, at the B3LYP/6-311++G(3df,3pd) level. These complexes ar ...
Full-Text PDF
... studied Rh catalyzed reaction pathways exhibited singlet ground state, as ruthenium homologous mechanism [50,65–68], but differently with respect to iron [42,43]. However, here the rhodium center might be disproportionate, or lose one chloride, like Castarlenas et al. have recently demonstrated [53] ...
... studied Rh catalyzed reaction pathways exhibited singlet ground state, as ruthenium homologous mechanism [50,65–68], but differently with respect to iron [42,43]. However, here the rhodium center might be disproportionate, or lose one chloride, like Castarlenas et al. have recently demonstrated [53] ...
Document
... • Two facts demonstrate that halogenation follows a different mechanism from that of hydrohalogenation or hydration. No rearrangements occur Only anti addition of X2 is observed These facts suggest that carbocations are not ...
... • Two facts demonstrate that halogenation follows a different mechanism from that of hydrohalogenation or hydration. No rearrangements occur Only anti addition of X2 is observed These facts suggest that carbocations are not ...
RUMPLE-DISSERTATION-2014 - SMARTech Home
... Eckert. The opportunity to work with such skilled scientists and kind mentors is a rare one, and I am extremely glad I had the opportunity to learn from them. I have always been in awe of their brilliance (I’m pretty sure they have each forgotten more than I’ll ever learn, and they still know so muc ...
... Eckert. The opportunity to work with such skilled scientists and kind mentors is a rare one, and I am extremely glad I had the opportunity to learn from them. I have always been in awe of their brilliance (I’m pretty sure they have each forgotten more than I’ll ever learn, and they still know so muc ...
Nucleophilic Substitution Reactions
... With a charged nucleophile (i.e. Nu: = HO or NC ) and a leaving group, LG H ...
... With a charged nucleophile (i.e. Nu: = HO or NC ) and a leaving group, LG H ...
NAME Chem 204 Spring, 1990 Final Exam FINAL EXAM: Chaps. 1
... Supplies: Common Solvents of all kinds: non-polar; hydroxylic; dipolar, aprotic Inorganic Reagents, including SOCl2, CO2, Mg, Na, K, Li, Al, NaN3, PX3, CrO3, ZnCl2, D2O, AgBr, AgNO3, RCN, NaSH, NaOH, NH3, H2SO4, HX (Cl, Br, I), NaSCN, NaH, KSCN, KCN, NaSH, NaOH, NH3, H2SO4, HX(Cl,Br,or I), NH2OSO3H, ...
... Supplies: Common Solvents of all kinds: non-polar; hydroxylic; dipolar, aprotic Inorganic Reagents, including SOCl2, CO2, Mg, Na, K, Li, Al, NaN3, PX3, CrO3, ZnCl2, D2O, AgBr, AgNO3, RCN, NaSH, NaOH, NH3, H2SO4, HX (Cl, Br, I), NaSCN, NaH, KSCN, KCN, NaSH, NaOH, NH3, H2SO4, HX(Cl,Br,or I), NH2OSO3H, ...
Chapter 4 - AP Chemistry with dr hart
... What happens when you mix an aqueous solution of sodium nitrate with an aqueous solution of barium chloride? a) There is no reaction; all possible products are soluble. ...
... What happens when you mix an aqueous solution of sodium nitrate with an aqueous solution of barium chloride? a) There is no reaction; all possible products are soluble. ...
VITA - Trace: Tennessee Research and Creative Exchange
... intermediate may follow several different reaction pathways, a Ru-imido is not thought to be the reaction intermediate. Yet the transfer of a nitrene from an imido complex is a possible target for a potential reaction intermediate. Upon examining isolated late transition metal imido complexes it be ...
... intermediate may follow several different reaction pathways, a Ru-imido is not thought to be the reaction intermediate. Yet the transfer of a nitrene from an imido complex is a possible target for a potential reaction intermediate. Upon examining isolated late transition metal imido complexes it be ...
Postprint
... need to extrude a phosphine group during the catalytic cycle.5 In turn, this discovery was carried across to iridium by Crabtree, leading to the synthesis of what is now known as Crabtree’s catalyst: [(COD)Ir(PCy3)(C5H5N)]PF6 (Figure 1.c).6 This catalyst was able to hydrogenate hexene and cyclohexen ...
... need to extrude a phosphine group during the catalytic cycle.5 In turn, this discovery was carried across to iridium by Crabtree, leading to the synthesis of what is now known as Crabtree’s catalyst: [(COD)Ir(PCy3)(C5H5N)]PF6 (Figure 1.c).6 This catalyst was able to hydrogenate hexene and cyclohexen ...
Group Meeting Special Topic: EJ Corey
... • First use in ring expansions and homologations • Dimethyloxosulfonium vs. Dimethylsulfonium ...
... • First use in ring expansions and homologations • Dimethyloxosulfonium vs. Dimethylsulfonium ...
Handout VI
... reaction and the equilibrium can be shifted to the right by using an acid or base as catalyst. In this case the rate limiting step is the attack of the nucleophile. This reaction proceeds quantitatively for aldehydes and simple ketones but not so for aryl alkyl ketones and diaryl ketones (Scheme 11) ...
... reaction and the equilibrium can be shifted to the right by using an acid or base as catalyst. In this case the rate limiting step is the attack of the nucleophile. This reaction proceeds quantitatively for aldehydes and simple ketones but not so for aryl alkyl ketones and diaryl ketones (Scheme 11) ...
Oxo-molybdenum(VI) - Repositório da Universidade Nova de Lisboa
... triggers its capability to catalyze different kind of processes such as carbon-carbon bond formation, olefin metathesis or alkene epoxidation among the most relevant transformations. ...
... triggers its capability to catalyze different kind of processes such as carbon-carbon bond formation, olefin metathesis or alkene epoxidation among the most relevant transformations. ...
Reactions at α-Position In preceding chapters on carbonyl chemistry
... Enolates are very useful to form new C-C bonds by reacting the enolate with alkyl halides ...
... Enolates are very useful to form new C-C bonds by reacting the enolate with alkyl halides ...
1H-Imidazol-4(5H)-ones and thiazol-4(5H)
... The most common pronucleophiles of this type are oxazol-5(4H)-ones or azlactones (Figure 1a, X = O), which have been thoroughly investigated and reviewed [23-25]. On the other hand, since the pionnering work by Trost in 2004 [26], several examples of the utility of the structurally related oxazol-4( ...
... The most common pronucleophiles of this type are oxazol-5(4H)-ones or azlactones (Figure 1a, X = O), which have been thoroughly investigated and reviewed [23-25]. On the other hand, since the pionnering work by Trost in 2004 [26], several examples of the utility of the structurally related oxazol-4( ...
Revised organic chemistry
... nucleophillic reagent find no site for attack on alkane molecules. Furthermore, the C-H and C-C bonds are strong bonds. Alkanes due to these types of strong bonds remain unaffected by acids, alkalies and oxidizing agents under ordinary conditions. ...
... nucleophillic reagent find no site for attack on alkane molecules. Furthermore, the C-H and C-C bonds are strong bonds. Alkanes due to these types of strong bonds remain unaffected by acids, alkalies and oxidizing agents under ordinary conditions. ...
Protection (and Deprotection) of Functional Groups in Organic
... In some instances, due to their insufficient acidity, prolonged reaction times or a large quantity of them are usually necessary, and, consequently, they are often modified by treatment with Lewis acids or protic acids (SA) to increase their catalytic activity. Similar procedures can be utilized to ...
... In some instances, due to their insufficient acidity, prolonged reaction times or a large quantity of them are usually necessary, and, consequently, they are often modified by treatment with Lewis acids or protic acids (SA) to increase their catalytic activity. Similar procedures can be utilized to ...
Resolution of Diols via Catalytic Asymmetric Acetalization
... although a higher catalyst loading was required (entry 4). When even more sterically demanding pivalaldehyde was used, the reaction did not proceed at all (entry 5). Considering that the use of isovaleraldehyde, which is bulkier than linear aldehydes and at the same time less bulky than α-trisubstit ...
... although a higher catalyst loading was required (entry 4). When even more sterically demanding pivalaldehyde was used, the reaction did not proceed at all (entry 5). Considering that the use of isovaleraldehyde, which is bulkier than linear aldehydes and at the same time less bulky than α-trisubstit ...
Ene reaction
The ene reaction (also known as the Alder-ene reaction) is a chemical reaction between an alkene with an allylic hydrogen (the ene) and a compound containing a multiple bond (the enophile), in order to form a new σ-bond with migration of the ene double bond and 1,5 hydrogen shift. The product is a substituted alkene with the double bond shifted to the allylic position.This transformation is a group transfer pericyclic reaction, and therefore, usually requires highly activated substrates and/or high temperatures. Nonetheless, the reaction is compatible with a wide variety of functional groups that can be appended to the ene and enophile moieties. Also,many useful Lewis acid-catalyzed ene reactions have been developed which can afford high yields and selectivities at significantly lower temperatures, making the ene reaction a useful C–C forming tool for the synthesis of complex molecules and natural products.