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TESIS DOCTORAL Dynamics and Synchronization in Neuronal Models
TESIS DOCTORAL Dynamics and Synchronization in Neuronal Models

... in detail the structure and concluded that the nervous system was composed of individual neurons rather than a continuum. For this discovery, Cajal was awarded with the 1906 Nobel Price in Medicine. Nowadays, neuroscience is a broad field where many disciplines converge to tackle questions like how ...
Structure and Function of Neurons - Assets
Structure and Function of Neurons - Assets

... Another anatomical zone is that of the axon hillock, also called the axon’s initial segment (Figure 1-8). Its job is to serve as an “electrical integrator” of all the incoming electrical information and decide whether or not to “fire” the neuron. Directly connected to the axon hillock is the axon its ...
Presentation Slides
Presentation Slides

... • Anxiety – behavioural state arising in anticipation of potential threat ...
the brain - Medical Research Council
the brain - Medical Research Council

... Multiple Sclerosis (MS) is the most common disabling neurological disorder affecting young adults in the UK. It is caused by the body’s own immune system attacking and damaging the myelin that surrounds and protects neurons. This interferes with messages between the brain and other parts of the body ...
Volitional enhancement of firing synchrony and oscillation by
Volitional enhancement of firing synchrony and oscillation by

... rate of these neurons, increasing the rate of some while simultaneously decreasing the rate of others. The subjects achieved this by focusing onto one image, which gradually became clearer on the computer screen, thereby overriding sensory input. On the basis of the firing of these MTL neurons, visu ...
Biosc_48_Chapter_9_lecture
Biosc_48_Chapter_9_lecture

... Sympathetic Division 1. Preganglionic neurons orginate from the thoracic and lumbar regions of the spinal cord. a. Also called the thoracolumbar division 2. Preganglionic neurons synapse in sympathetic ganglia that run parallel to the spinal cord. a. These are called the paravertebral ganglia. b. T ...
IOSR Journal of Electrical and Electronics Engineering (IOSR-JEEE)
IOSR Journal of Electrical and Electronics Engineering (IOSR-JEEE)

... background activity in tense and anxious subjects. The absence of the normal (expected) rhythm in a certain state of the subject could indicate abnormality. The presence of delta or theta (slow) waves in a wakeful adult would be considered to be abnormal. Focal brain injury and tumors lead to abnorm ...
Hyperhidrosis Due to Thalamic Deep Brain Stimulation in a Patient
Hyperhidrosis Due to Thalamic Deep Brain Stimulation in a Patient

... of VIM (ventrointermedius) deep brain stimulation. BACKGROUND: Essential tremor (ET) is a the most common form of tremor encountered in movement disorder clinics. ET is characterized by postural and action tremor of the upper extremities, but head, voice, and lower extremity tremors may also be pres ...
MUSK Antibody
MUSK Antibody

... activation of ABL1 and Src family kinases which in turn regulate MUSK. DVL1 and PAK1 that form a ternary complex with MUSK are also important for MUSK-dependent regulation of AChR clustering. May positively regulate Rho family GTPases through FNTA. Mediates the phosphorylation of FNTA which promotes ...
Zebrafish and motor control over the last decade
Zebrafish and motor control over the last decade

... activity of individual neurons in intact zebrafish (O'Donovan et al., 1993). This allowed the first imaging of neuronal activity with single cell resolution in an intact vertebrate (Fetcho and O'Malley, 1995). The first work was largely technical, both documenting the ability to reliably image group ...
ling411-11-Columns - OWL-Space
ling411-11-Columns - OWL-Space

... Similarly..  Neurons of a hypercolumn may have similar response features, upon which others that differ may be superimposed  Result is maxicolumns in the hypercolumn sharing certain basic features while differing with respect to others  Such maxicolumns may be further subdivided into functional ...
Trial and Error – Optogenetic techniques offer insight into the
Trial and Error – Optogenetic techniques offer insight into the

... input-output function of identified dopamine neurons and to determine how expectation transforms this function. We found that dopamine neurons use simple subtraction (9) [see the figure (B)]. Although this arithmetic is assumed in computational models, it is remarkably rare in the brain; division is ...
Pierre Berthet Computational Modeling of the Basal Ganglia – Functional Pathways
Pierre Berthet Computational Modeling of the Basal Ganglia – Functional Pathways

... We perceive the environment via sensor arrays and interact with it through motor outputs. The work of this thesis concerns how the brain selects actions given the information about the perceived state of the world and how it learns and adapts these selections to changes in this environment. This lea ...
Chapter 15: Neural Integration I: Sensory Pathways and the Somatic
Chapter 15: Neural Integration I: Sensory Pathways and the Somatic

... a. It must therefore be an ascending tract that carries sensory information. 2. The rest of the name indicates the tract’s destination. a. A spinothalamic tract begins in the spinal cord and carries sensory information to the thalamus. 3. If the name of a tract ends in –spinal, the tract ends in the ...
neuronal coding of prediction errors
neuronal coding of prediction errors

... outcomes (reward, punishment, behavioral reactions, external stimuli, internal states). Outcomes whose magnitude or frequency is different than predicted modify behavior in a direction that reduces the discrepancy between the outcome and its prediction. Changes in predictions and behavior continue u ...
The epistemic value of brain-machine systems for the study of the
The epistemic value of brain-machine systems for the study of the

... the authors have drawn interesting insights on the functioning of the (monkey) nervous system from data obtained during the “pole control” (Figure 1) and “brain control” (Figures 2 and 3) stages. Let me start from the “pole control” phase. As pointed out before, at the end of this phase a fairly goo ...
motor systems
motor systems

... cortical areas also participate of some kinematic and dynamic movement parameters. The non-primary motor areas appear more specialized, however, for selecting and controlling movements made in particular behavioral contexts, such as when the direction of a movement to be made must be remembered or w ...
Chapter 14: Brain Control of Movement
Chapter 14: Brain Control of Movement

... The Contributions of Posterior Parietal and Prefrontal Cortex (Cont’d) Anterior frontal lobes: Abstract thought, decision making and anticipating consequences of action Area 6: Actions converted into signals specifying how actions will be performed Per Roland Monitored cortical activation accompany ...
neuro 2009 - addiction education home
neuro 2009 - addiction education home

... differences among the subgroups as the alcoholic group was much worse followed by the amphetamine then the opioids groups. Patients with longer duration of dependence and multiple hospital readmissions were much worse in comparison to patients with shorter duration of dependence and less readmission ...
The Basal Ganglia and Chunking of Action Repertoires
The Basal Ganglia and Chunking of Action Repertoires

... the projection neurons have both non-NMDA and NMDA receptors (Kita, 1996). When the projection neurons are in down-state, NMDA receptors are blocked, and glutamate acts through AMPA/kainate receptors. Under conditions of strong and temporally coherent activation, driving the neurons into up-state, N ...
Changes in 3H-Substance P Receptor Binding in the Rat Brain After
Changes in 3H-Substance P Receptor Binding in the Rat Brain After

... No significant differences were noted between the results obtained from rats that survived 4 d or 21 d after the unilateral lesion of the corpus striatum. Discussion ...
NEURAL NETWORK DYNAMICS
NEURAL NETWORK DYNAMICS

... input. In mathematical terms, we need to understand how a system can reconcile a rich internal state structure with a high degree of sensitivity to external variables. This problem is far from solved, but here we review progress that has been made in recent years. Rather than surveying a large numbe ...
Neurological Anatomy and Physiology
Neurological Anatomy and Physiology

... Information from one neuron flows to another neuron across synapses. The synapse is a small gap separating neurons. It consists of a pre-synaptic ending that contains neurotransmitters, mitochondria and other cell structures, a postsynaptic ending that contains receptor sites for neurotransmitters, ...
Properties of Primary Sensory (Lemniscal) Synapses in the
Properties of Primary Sensory (Lemniscal) Synapses in the

... sensory inputs to the neocortex. In the primary somatosensory thalamus (ventrobasal thalamus), sensory inputs deliver tactile information through the medial lemniscus tract. The transmission of sensory information through this pathway is affected by behavioral state. For instance, the relay of high- ...
Preview Sample 1
Preview Sample 1

... Neurons have four major components: a soma, dendrites, axon, and axon terminal. The soma is the body of the neuron. It also contains the nucleus, which holds DNA. Overall, components within the soma support a neuron’s basic physiological processes. Generally, a neuron has many dendrites that branch ...
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Activity-dependent plasticity

A defining feature of the brain is its capacity to undergo changes based on activity-dependent functions, also called activity-dependent plasticity. Its ability to remodel itself forms the basis of the brain’s capacity to retain memories, improve motor function, and enhance comprehension and speech amongst other things. It is this trait to retain and form memories that is functionally linked to plasticity and therefore many of the functions individuals perform on a daily basis. This plasticity is the result of changed gene expression that occurs because of organized cellular mechanisms.The brain’s ability to adapt toward active functions has allowed humans to specialize in specific processes based on relative use and activity. For example, a right-handed person may perform any movement poorly with his/her left hand but continuous practice with the less dominant hand can make both hands just as able. Another example is if someone was born with a neurological disorder such as autism or had a stroke that resulted in a disorder, then they are capable of retrieving much of their lost function by practicing and “rewiring” the brain in order to incorporate these lost manners. Thanks to the pioneers within this field, many of these advances have become available to most people and many more will continue to arrive as new features of plasticity are discovered.
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