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Interval time coding by neurons in the presupplementary and
Interval time coding by neurons in the presupplementary and

... exclusive relationship to one of the three hold times was smaller (n ¼ 2) hold times. However, 36 neurons showed a graded type of selectivity to than in the preSMA neurons. However, 55 SMA neurons showed the hold time. Notably, for one population of these neurons, the graded selectivity to the hold ...
View PDF - CiteSeerX
View PDF - CiteSeerX

... experimentally altered task constraints,(27–30) drug administration,(3,31,32) and pathologies such as Parkinson’s disease.(1,2) The decision or comparison component is described as a mechanism that evaluates how well the current clock value matches previously stored temporal memories, and can be inf ...
NT Notes
NT Notes

... This powerpoint will help you with your WS and with the computer based activity. You do not need to memorize this info, just understand it as we discuss it. Later: you will have a reference sheet to look at while you do your WS. This is a class set so please do not take them with you. It is also ava ...
Seeing Early Signs of Alzheimer`s Disease Through the Lens of the
Seeing Early Signs of Alzheimer`s Disease Through the Lens of the

... cognitive and behavioral impairments. The main neuropathological hallmark of AD is the accumulation of amyloidbeta (Aβ) peptide produced by successive proteolytic cleavage from its precursor APP (amyloid-beta precursor protein) along the amyloidogenic pathway [3]. Aβ accumulates extracellularly as a ...
Thermal impact on spiking properties in Hodgkin–Huxley neuron
Thermal impact on spiking properties in Hodgkin–Huxley neuron

... explore the biophysical origin of this phenomenon associated with ion channel gating kinetics and also discuss its possible biological relevance in information processing in neuronal systems. Keywords. Thermal impact; spiking threshold; ion channel kinetics; synaptic transmission. PACS Nos 87.17.Aa; ...
Adaptive Behavior - Server users.dimi.uniud.it
Adaptive Behavior - Server users.dimi.uniud.it

... on their steric properties. By introducing such a neuromodulator concept synaptic changes on a different time scale can be investigated, because the interactions between neuromodulators and receptors allow an immediate change of the synaptic information transfer. As there is no current existing theo ...
Mapping Function Onto Neuronal Morphology
Mapping Function Onto Neuronal Morphology

... model a developmental process. This method encodes dendritic morphologies in a compact way and allows the GAs to search efficiently for optimized neuronal morphologies. The approach used by Samsonovich and Ascoli (2005) was simplified here to encode the input parameters and initial conditions to mak ...
CONTROL OF FOOD INTAKE: NEUROBIOLOGICAL ASPECTS S
CONTROL OF FOOD INTAKE: NEUROBIOLOGICAL ASPECTS S

... Since the pioneering work by Hetherington and Ranson (1940), it has been well established that the central nervous system plays a pivotal role in food intake regulation. Indeed, any defect in the functioning of the neuronal networks involved in feeding results in severe morbidity, such as anorexia o ...
review glutamate and gaba receptor signalling in - lópez
review glutamate and gaba receptor signalling in - lópez

... Abstract—Our understanding of the role played by neurotransmitter receptors in the developing brain has advanced in recent years. The major excitatory and inhibitory neurotransmitters in the brain, glutamate and GABA, activate both ionotropic (ligand-gated ion channels) and metabotropic (G protein-c ...
The neural basis of the speed–accuracy tradeoff - Eric
The neural basis of the speed–accuracy tradeoff - Eric

... Many decisions are based on information that accumulates over time. Is the approaching animal a predator or a prey? Should I take the next exit on a busy highway? What restaurant do I want to dine at tonight? For such decisions, one faces a dilemma that is known as the speed–accuracy tradeoff (SAT; ...
The Nervous System
The Nervous System

... – The opening of these channels accelerates the movement of ions across the plasma membrane, resulting in a change in membrane potential • Depolarization is a shift towards a more positive (0 mV) membrane potential – Ex) The opening of gated sodium channels accelerates the entry of Na+ into the cell ...
Cellular scaling rules for the brain of afrotherians
Cellular scaling rules for the brain of afrotherians

... cortex in all animals was manually dissected from the striatum and other subcortical structures. The hippocampus was then dissected from each cortical hemisphere, under a stereoscope. The cerebral cortex of the hyrax specimens was then cut into 2 mm coronal sections in order to allow the dissection ...
Morphomechanics: transforming tubes into organs
Morphomechanics: transforming tubes into organs

... size on the ventral side of the HT during c-looping (Figure 1b), which would be consistent with bending driven by differential hypertrophic growth. This finding was unexpected, because it had been commonly thought that the heart grows primarily by hyperplasia before birth and hypertrophy after birth ...
Vol 431 No 7010 pp723-882
Vol 431 No 7010 pp723-882

... been infused with concepts taken from computational theories of reinforcement learning. These more abstract approaches have now been applied to describe the biological algorithms at play in our brains when we form value judgements and make choices. The application of such quantitative models has ope ...
THE NEURON
THE NEURON

... Dendrites receive impulses from other neurons and carry impulses to the cell body. ...
Rate versus Temporal Coding Models
Rate versus Temporal Coding Models

... All theories about how the brain functions are based on the idea that information is represented by the electrical activity of neurons. The question of how neurons represent information is therefore fundamental to all branches of neuroscience. What is the neural code of information, and how is it us ...
Differential Roles of the Frontal Cortex, Basal Ganglia, and
Differential Roles of the Frontal Cortex, Basal Ganglia, and

... set, though the activity varied with different sets. For the learned hypersets, the neuron fired only at the very beginning: before the first button press for the first set of the first trial. The preference for new sequences was fairly common among neurons in the pre-SMA. A considerable portion of ...
The caudal part of the frontal cortex is strongly involved - LIRA-Lab
The caudal part of the frontal cortex is strongly involved - LIRA-Lab

... by another individual, if the seen action is similar to that motorically coded by them (di Pellegrino, et al., 1992; Gallese et al., 1996; Rizzolatti et al., 1996). In contrast to the canonical neurons, mirror neurons do not respond to the mere presentation of objects. Thus, the vision of a real act ...
The Ventrolateral Hypothalamic Area and the Parvafox Nucleus
The Ventrolateral Hypothalamic Area and the Parvafox Nucleus

... the PV1-Foxb1 nucleus and which we now propose to call the parvafox nucleus. Here, we review the circumstantial evidence pointing to a role of the ventral LHA in the expression of emotions. To this end, we will draw on data that concern the parvafox as an entry point. We will avoid referring to the ...
Dendrite structure
Dendrite structure

... What is the purpose of dendrites? Why do they exhibit such an overwhelming variety and complexity of shapes? How are their shapes related to neuronal function? Ramón y Cajal posed and, to a remarkable degree, answered these questions 100 years ago in his Histology of the Nervous System (Ramón y Caja ...
3 Behavioral Neuroscience - McGraw Hill Higher Education
3 Behavioral Neuroscience - McGraw Hill Higher Education

... studies how heredity affects behavior. Research in behavioral genetics has found evidence of a hereditary basis for characteristics as diverse as divorce (Jocklin, McGue, & Lykken, 1996), empathy (Plomin, 1994), and intelligence (Petrill & Wilkerson, 2000). To appreciate behavioral genetics, it help ...
energy balance
energy balance

... Leptin alter synaptic function • Leptin alter the strength of excitatory synaptic transmission under conditions of enhanced Excitability . – In certain conditions leptin cause hippocampal long-term depression (LTD) – In contrasts leptin under physiological conditions (1 mM Mg2+), it promotes the in ...
Dendrite structure
Dendrite structure

... What is the purpose of dendrites? Why do they exhibit such an overwhelming variety and complexity of shapes? How are their shapes related to neuronal function? Ramón y Cajal posed and, to a remarkable degree, answered these questions 100 years ago in his Histology of the Nervous System (Ramón y Caja ...
Tom`s JSNC2000 paper
Tom`s JSNC2000 paper

... directions this particular technique will take us. For example, one day we hope to study whether any changes that do occur as a result of experience within the virtual environments we create are similar to the changes one would expect to see from phenomena reflecting some basic forms of learning suc ...
Autonomic nervous system
Autonomic nervous system

... integrates all visceral information. The nTS also receives input from a nearby chemosensory center, the area postrema, that detects toxins in the blood and the ...
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Activity-dependent plasticity

A defining feature of the brain is its capacity to undergo changes based on activity-dependent functions, also called activity-dependent plasticity. Its ability to remodel itself forms the basis of the brain’s capacity to retain memories, improve motor function, and enhance comprehension and speech amongst other things. It is this trait to retain and form memories that is functionally linked to plasticity and therefore many of the functions individuals perform on a daily basis. This plasticity is the result of changed gene expression that occurs because of organized cellular mechanisms.The brain’s ability to adapt toward active functions has allowed humans to specialize in specific processes based on relative use and activity. For example, a right-handed person may perform any movement poorly with his/her left hand but continuous practice with the less dominant hand can make both hands just as able. Another example is if someone was born with a neurological disorder such as autism or had a stroke that resulted in a disorder, then they are capable of retrieving much of their lost function by practicing and “rewiring” the brain in order to incorporate these lost manners. Thanks to the pioneers within this field, many of these advances have become available to most people and many more will continue to arrive as new features of plasticity are discovered.
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