Voltage-Sensitive Dye Imaging: Technique review and Models
... (VSDI). This optical imaging technique offers the possibility to visualize, in real time, the cortical activity of large neuronal populations with high spatial resolution (down to 20-50 µm) and high temporal resolution (down to the millisecond). With such resolutions, VSDI appears to be the best tec ...
... (VSDI). This optical imaging technique offers the possibility to visualize, in real time, the cortical activity of large neuronal populations with high spatial resolution (down to 20-50 µm) and high temporal resolution (down to the millisecond). With such resolutions, VSDI appears to be the best tec ...
Anticipated synchronization in neuronal circuits
... provided either by an interneuron or by a subpopulation of inhibitory neurons. A smooth transition from delayed synchronization (DS) to AS typically occurs when the inhibitory synaptic conductance is increased. The phenomenon is shown to be robust for a wide range of model parameters within a physio ...
... provided either by an interneuron or by a subpopulation of inhibitory neurons. A smooth transition from delayed synchronization (DS) to AS typically occurs when the inhibitory synaptic conductance is increased. The phenomenon is shown to be robust for a wide range of model parameters within a physio ...
The Role of Dopamine and Its Dysfunction as a Consequence of
... of peroxynitrite results in damage to target molecules and leads to pathological disorders, as was reported by Afanas’ev [27]. This author suggested that superoxide signaling depends on nucleophilic reactions. It is necessary to clarify that an oxidant is an element or compound in an oxidationreduct ...
... of peroxynitrite results in damage to target molecules and leads to pathological disorders, as was reported by Afanas’ev [27]. This author suggested that superoxide signaling depends on nucleophilic reactions. It is necessary to clarify that an oxidant is an element or compound in an oxidationreduct ...
Synaptic and peptidergic connectome of a neurosecretory
... anatomically and ultrastructurally distinct area that can be clearly distinguished from other neuropils, including the adjacent optic and nuchal organ neuropils (Randel et al. 2014; Shahidi et al. 2015) (Figure 1D). Neurites in this area have a high number of dense-core vesicles and very few synapse ...
... anatomically and ultrastructurally distinct area that can be clearly distinguished from other neuropils, including the adjacent optic and nuchal organ neuropils (Randel et al. 2014; Shahidi et al. 2015) (Figure 1D). Neurites in this area have a high number of dense-core vesicles and very few synapse ...
here - University of California San Diego
... Increased synaptic connectivity due to sensory axon plasticity. Using our conditioning lesion paradigm by injecting trace amount of EtBr, proprioceptive axon plasticity is greatly increased, resulting in greater extent of regeneration than sciatic nerve crush (manuscript in press, 10.1016/j.expneuro ...
... Increased synaptic connectivity due to sensory axon plasticity. Using our conditioning lesion paradigm by injecting trace amount of EtBr, proprioceptive axon plasticity is greatly increased, resulting in greater extent of regeneration than sciatic nerve crush (manuscript in press, 10.1016/j.expneuro ...
Electrophysiological recordings from behaving animals—going
... analysis tools that enable extraction of high order interaction between the recorded units (for review see [24] and [25]). Another direction is trying to extrapolate information on intrinsic properties of the units from extracellular waveforms. To this end dual intracellular and extracellular recor ...
... analysis tools that enable extraction of high order interaction between the recorded units (for review see [24] and [25]). Another direction is trying to extrapolate information on intrinsic properties of the units from extracellular waveforms. To this end dual intracellular and extracellular recor ...
Competitive Dynamics in Cortical Responses to Visual Stimuli
... Huxley-type conductance-based neurons. The network was an abstracted canonical cortical circuit (Douglas and Martin 2004; Raizada and Grossberg 2003) consisting of two excitatory and two inhibitory pools of 40 neurons each (Fig. 2A). Increases beyond this number had no appreciable effect on the resu ...
... Huxley-type conductance-based neurons. The network was an abstracted canonical cortical circuit (Douglas and Martin 2004; Raizada and Grossberg 2003) consisting of two excitatory and two inhibitory pools of 40 neurons each (Fig. 2A). Increases beyond this number had no appreciable effect on the resu ...
Diverse functions of perineuronal nets
... These results indicate that tenascin-R is essential for ECM proteoglycans to form the lattice-like structure (Weber et al. 1999, Haunso et al. 2000). It appears that precise timing of the CS proteoglycans expression seems to be specific for both cortical areas and particular cortical layers. For exa ...
... These results indicate that tenascin-R is essential for ECM proteoglycans to form the lattice-like structure (Weber et al. 1999, Haunso et al. 2000). It appears that precise timing of the CS proteoglycans expression seems to be specific for both cortical areas and particular cortical layers. For exa ...
Neuronal Competition and Selection During Memory Formation
... may be important for selecting the neurons that participate in encoding memories in the adult brain. To examine neuronal competition during memory formation, we conducted experiments with mice in which we manipulated the function of CREB (adenosine 3´,5´-monophosphate response element–binding protei ...
... may be important for selecting the neurons that participate in encoding memories in the adult brain. To examine neuronal competition during memory formation, we conducted experiments with mice in which we manipulated the function of CREB (adenosine 3´,5´-monophosphate response element–binding protei ...
Synaptic Integration in Rat Frontal Cortex Shaped by Network Activity
... neurons. A: example of simultaneous intracellular recording of a neuron together with several other neurons recorded extracellularly with 4 tetrodes inserted in close vicinity (⬍400 m). Top: 10 s of intracellular recording of a neocortical pyramidal neuron. Middle: 4 traces of simultaneous multiuni ...
... neurons. A: example of simultaneous intracellular recording of a neuron together with several other neurons recorded extracellularly with 4 tetrodes inserted in close vicinity (⬍400 m). Top: 10 s of intracellular recording of a neocortical pyramidal neuron. Middle: 4 traces of simultaneous multiuni ...
Temporary inhibition of AMPA receptors induces a prolonged improvement
... The Cln3-knockout (Cln3Dex1e6) mouse model of JNCL exhibits many characteristic features of the human disorder, including a deficit in cerebellar motor coordination (Kovacs et al., 2006; Mitchison et al., 1999; Weimer et al., 2009). Exploring the possible cause(s) of the functional impairment of the ...
... The Cln3-knockout (Cln3Dex1e6) mouse model of JNCL exhibits many characteristic features of the human disorder, including a deficit in cerebellar motor coordination (Kovacs et al., 2006; Mitchison et al., 1999; Weimer et al., 2009). Exploring the possible cause(s) of the functional impairment of the ...
Neural integration
... Primary motor cortex corresponds point by point with specific regions of the body Cortical areas have been mapped out in diagrammatic form Homunculus provides indication of degree of fine motor control available: – hands, face, and tongue, which are capable of varied and complex movements, app ...
... Primary motor cortex corresponds point by point with specific regions of the body Cortical areas have been mapped out in diagrammatic form Homunculus provides indication of degree of fine motor control available: – hands, face, and tongue, which are capable of varied and complex movements, app ...
Chapter 13
... C.fat accumulates in the liver; also, liver cells die D.immune system functioning declines E.All of the choices are correct. 24. Reflex centers for visual, auditory, and tactile responses are located in which part of the brain? A.midbrain B.corpus callosum C.cerebrum D.medulla oblongata E.cerebellum ...
... C.fat accumulates in the liver; also, liver cells die D.immune system functioning declines E.All of the choices are correct. 24. Reflex centers for visual, auditory, and tactile responses are located in which part of the brain? A.midbrain B.corpus callosum C.cerebrum D.medulla oblongata E.cerebellum ...
Clarinet (CLA-‐1), a novel active zone protein required for
... domain is most similar to that of RIM, but constitutes a distinct clade (fig. 1I). This result, along with the ...
... domain is most similar to that of RIM, but constitutes a distinct clade (fig. 1I). This result, along with the ...
Clarinet (CLA-‐1), a novel active zone protein required for synaptic
... domain is most similar to that of RIM, but constitutes a distinct clade (fig. 1I). This result, along with the ...
... domain is most similar to that of RIM, but constitutes a distinct clade (fig. 1I). This result, along with the ...
Predicting functional neuroanatomical maps from fusing
... A central aim, from basic neuroscience to psychiatry, is to resolve how genes control brain circuitry and behavior. This is experimentally hard, since most brain functions and behaviors are controlled by multiple genes. In low throughput, one gene at a time, experiments, it is therefore difficult to ...
... A central aim, from basic neuroscience to psychiatry, is to resolve how genes control brain circuitry and behavior. This is experimentally hard, since most brain functions and behaviors are controlled by multiple genes. In low throughput, one gene at a time, experiments, it is therefore difficult to ...
State of the art
... expression of disease that differs among individuals. It is not just the dramatic stressful events that exact their toll, but rather the many events of daily life that elevate and sustain activities of physiological systems and cause sleep deprivation, overeating, and other health-damaging behaviors ...
... expression of disease that differs among individuals. It is not just the dramatic stressful events that exact their toll, but rather the many events of daily life that elevate and sustain activities of physiological systems and cause sleep deprivation, overeating, and other health-damaging behaviors ...
Neurobilogy of Sleep
... hypothalamus (Hcrt). • The TMN firing rate is high during wake, lower during NREM, and absent during REM . • In contrast to REM sleep, during attacks of cataplexy, TMN neurons have a high firing rate associated with preservation of consciousness. • Low CSF HA has been found in patients with narcolep ...
... hypothalamus (Hcrt). • The TMN firing rate is high during wake, lower during NREM, and absent during REM . • In contrast to REM sleep, during attacks of cataplexy, TMN neurons have a high firing rate associated with preservation of consciousness. • Low CSF HA has been found in patients with narcolep ...
- Philsci
... In the following discussion I will assume that mechanistic models describe the regular behaviour of system components by means of generalizations (Glennan, 2005; Woodward, 2002). The term “model” is used here to emphasize the fact that mechanism descriptions may be more or less abstract in the sense ...
... In the following discussion I will assume that mechanistic models describe the regular behaviour of system components by means of generalizations (Glennan, 2005; Woodward, 2002). The term “model” is used here to emphasize the fact that mechanism descriptions may be more or less abstract in the sense ...
PDF
... variability due to gross physiological noise. Average maps from a sample of 45 healthy individuals scanned in the resting state show a clear and symmetric pattern of connectivity maxima in several regions of cortex, including prefrontal, orbitofrontal, lateral–parietal, and midline default mode netw ...
... variability due to gross physiological noise. Average maps from a sample of 45 healthy individuals scanned in the resting state show a clear and symmetric pattern of connectivity maxima in several regions of cortex, including prefrontal, orbitofrontal, lateral–parietal, and midline default mode netw ...
Abstracts - BCCN 2009
... The Bernstein Focus for Neurotechnology Frankfurt has started operation less than a year ago. We are happy to be part of this network and honored to have the opportunity to organize this meeting. As in previous years, there will be a single track program of talks and poster sessions. In line with th ...
... The Bernstein Focus for Neurotechnology Frankfurt has started operation less than a year ago. We are happy to be part of this network and honored to have the opportunity to organize this meeting. As in previous years, there will be a single track program of talks and poster sessions. In line with th ...
ling411-19-Learning - OWL-Space
... Genetic factors determine general area for a particular type of knowledge Within this general area the learning-based proximity factors select a more narrowly defined location Thus the exact localization depends on experience of the individual When part of the system is damaged, learning-bas ...
... Genetic factors determine general area for a particular type of knowledge Within this general area the learning-based proximity factors select a more narrowly defined location Thus the exact localization depends on experience of the individual When part of the system is damaged, learning-bas ...
Identification of Mechanoafferent Neurons in Terrestrial Snail
... the animal and pinned to a silicone-elastomer (Sylgard)-coated dish. Connective tissue sheath was partially removed using fine forceps and scissors. To facilitate further desheathing, ganglia were treated with Protease (0.25 mg/ml; Type XIV, Sigma) for 30 min at room temperature and washed out, and ...
... the animal and pinned to a silicone-elastomer (Sylgard)-coated dish. Connective tissue sheath was partially removed using fine forceps and scissors. To facilitate further desheathing, ganglia were treated with Protease (0.25 mg/ml; Type XIV, Sigma) for 30 min at room temperature and washed out, and ...
prenatal formation of cortical input and development of
... distribution of ingrowing terminals synchronized with changes in cellular organization of the neostriatum. ...
... distribution of ingrowing terminals synchronized with changes in cellular organization of the neostriatum. ...