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Septins promote dendrite and axon development by negatively
Septins promote dendrite and axon development by negatively

... NATURE COMMUNICATIONS | 4:2532 | DOI: 10.1038/ncomms3532 | www.nature.com/naturecommunications ...
Neuronal Clusters in the Primate Motor Cortex during Interception of
Neuronal Clusters in the Primate Motor Cortex during Interception of

... (Figure 5, top). Activity of these two clusters diverged, however, near the movement onset. While activity of Cluster 4 began to decline near the movement onset, activity of Cluster 1 continued throughout the movement, decreasing with a time course more similar to that of the hand velocity. Activity ...
Attention-Deficit Hyperactivity Disorder
Attention-Deficit Hyperactivity Disorder

... The imaging findings make sense because the brain areas that are reduced in size in children with ADHD are the very ones that regulate attention. The right prefrontal cortex, for example, is involved in “editing” one’s behavior, resisting distractions and developing an awareness of self and time. Th ...
ARTICULOS PUBLICADOS EN REVISTAS ELECTRÓNICAS:  TRABAJO 1:
ARTICULOS PUBLICADOS EN REVISTAS ELECTRÓNICAS: TRABAJO 1:

... during the inhibition was reduced on average to 13% of pre-stimulus firing rate. Table 1 shows the characteristics of these inhibitions, classified according to the stimulation site (DR or MnR). There were no significant differences in the characteristics of the inhibitions between those elicited by ...
In Vivo Evaluation of White Matter Integrity and Anterograde
In Vivo Evaluation of White Matter Integrity and Anterograde

... necrotic and apoptotic cell death in the retina and the brain are also dependent on the types and amount of glutamate receptors involved at the site of insult.16,39 As abnormalities in glutamate metabolism were suggested to play a vital role in human diseases such as retinal ischemia,5 glaucoma,11 a ...
Genetic dissection of neural circuits underlying sexually dimorphic
Genetic dissection of neural circuits underlying sexually dimorphic

... epigenetic environments of males and females during development and adulthood [1–6]. Hormones such as oestrogens and androgens exert their effects by binding to their respective membrane-bound and nuclear receptors [7 –8]. Nuclear oestrogen and androgen receptors (ARs) are transcription factors that ...
Full text article
Full text article

... Establishment of the hypothalamic-hypophyseal-gonadal function is dependent on the highly controlled and dynamic interactions between regulatory signals from the brain, pituitary and gonads, all of them leading to the attainment of reproductive capacity, where a coordinated and timely activation of ...
Behavioral flexibility is increased by optogenetic inhibition of
Behavioral flexibility is increased by optogenetic inhibition of

... results. Neural activity in these different time segments—response selection, reward expectancy, and reward delivery—may therefore play a specific causal role in response selection. Correlation of activation and inhibition of neural activity with behavior establishes the possibility of a causal rela ...
Electrophysiological Identification of Tonic and Phasic Neurons in
Electrophysiological Identification of Tonic and Phasic Neurons in

... afterhyperpolarization (AHP) and increased the number of action potential firings. In phasic neurons, however, the same treatments caused less change in these electrophysiological parameters except for increased overshoot and decreased AP durations. We concluded that tonic neurons and phasic neurons ...
Neuronal Activation in the Medulla Oblongata During Selective
Neuronal Activation in the Medulla Oblongata During Selective

... same neural pathways may be involved in each. Our interest is in which part of these pathways are involved when only the LAR is elicited. Because the LAR can be elicited using a single stimulus (Sasaki and Suzuki 1976), we used a very low rate of stimulation, 0.5 Hz, to prevent the occurrence of swa ...
The Neurology of Music for Post-Traumatic-Stress
The Neurology of Music for Post-Traumatic-Stress

... the person in danger the energy to fight or flee. Too much cortisol in the body can take a physical, mental, and emotional toll on the body. It also plays a significant role in the physiology behind PTSD symptoms (Ehlert, Gaab, & Heinrichs, 2001). Now that trauma and stress were differentiated, a re ...
[Frontiers in Bioscience 8, s438-451, May 1, 2003] 438 AROUSAL
[Frontiers in Bioscience 8, s438-451, May 1, 2003] 438 AROUSAL

... reticular formation (19). They thus have the capacity to receive input from reticular neurons and also the noradrenergic locus coeruleus neurons, which utilize the same pathway (see below). The cholinergic neurons give rise to ascending projections that parallel those of the reticular formation, ext ...
Stimulus Dependence of Local Field Potential Spectra: Experiment
Stimulus Dependence of Local Field Potential Spectra: Experiment

... power is concentrated at low frequencies. This is a very natural choice for a model of external inputs to V1 during presentation of a natural movie because time changes of visual features in natural movies have been reported, both in general (Wong and Atick, 1995) and for the particular movies used ...
PDF
PDF

... from the Institutional Animal Care and Use Committee. A procedural timeline is presented in Figure 1. Monkeys were assigned randomly to 1 of 2 groups, differing only with regard to whether they received postinfarct injections of GSK249320 (experimental group) or vehicle (control group). One investig ...
Non-reward neural mechanisms in the orbitofrontal cortex
Non-reward neural mechanisms in the orbitofrontal cortex

... received a reward, and this has been quantified in a more recent study (Berlin et al., 2004). The importance of the failure to rapidly learn about the value of stimuli from negative feedback has also been described as a critical difficulty for patients with orbitofrontal cortex lesions (Fellows, 200 ...
Neuronal mechanisms of executive control by the prefrontal cortex
Neuronal mechanisms of executive control by the prefrontal cortex

... memory model. Since it would be difficult for a defective central executive to oversee the simultaneous and coordinated operation of two slave systems (the visuospatial sketchpad and the phonological loop) in their model, they proposed that the executive control can be analyzed using a dual-task par ...
Cuneiform Neurons Activated during
Cuneiform Neurons Activated during

... of 4% paraformaldehyde, 15% saturated picric acid, and 0.25% glutaraldehyde in 0.1 M phosphate buffer at pH 7.4. The brainstem was removed and immersed for a 24 hr post-fixation period in a solution consisting of 2% paraformaldehyde and 15% saturated picric acid in 0.1 M phosphate buffer at pH 7.4. ...
Review Inhibitory neurotransmission, plasticity and aging in the
Review Inhibitory neurotransmission, plasticity and aging in the

... Steinschneider et al., 2008). A1 has been shown to undergo agerelated plastic changes, including down-regulation of inhibitory coding, similar to that observed at lower levels of the auditory pathway and in visual cortex. Similar to age-related changes, activity-dependant changes have been shown to ...
Turtle Dorsal Cortex Pyramidal Neurons Comprise Two Distinct Cell
Turtle Dorsal Cortex Pyramidal Neurons Comprise Two Distinct Cell

... Procedures used in this study were approved by Washington University’s Institutional Animal Care and Use Committee and conform to the guidelines of the National Institutes of Health on the Care and Use of Laboratory Animals. Red-eared slider turtles (Trachemys scripta elegans, 150–200 g weight, 12–1 ...
Gustatory Processing in Drosophila Higher Brain Centers By
Gustatory Processing in Drosophila Higher Brain Centers By

... was not identified until much later. This gene is preferentially expressed in the dorsal paired medial (DPM) neurons (Waddell et al., 2000), which have been shown to play an important role in memory consolidation. These genetic studies, and many others like them, have produced profound insights into ...
MS Word DOC - AvianBrain.org
MS Word DOC - AvianBrain.org

... major histogenetic divisions: the pallium and the subpallium. The existence of these two divisions is based on developmental, molecular, and connectivity data explained below. If we consider the telencephalon isolated from the rest of the brain, the pallium is located at the top of the telencephalic ...
Articles in PresS. J Neurophysiol (March 20, 2003). 10.1152/jn
Articles in PresS. J Neurophysiol (March 20, 2003). 10.1152/jn

... between these inputs that determines the membrane potential of the up state. The two K+ currents included in our model, Kir2 and Ksi (si, slowly inactivating), have been shown (Nisenbaum and Wilson 1995) to account for the characteristic nonlinear voltage dependence of the outward current measured i ...
Adaptive Gain and Optimal Performance
Adaptive Gain and Optimal Performance

... mode, associated with disengagement from the current task and a search for alternative behaviors (exploration). Monkey LC receives prominent, direct inputs from the anterior cingulate (ACC) and orbitofrontal cortices (OFC), both of which are thought to monitor task-related utility. We propose that t ...
Acetylcholine and appetitive behavior 1
Acetylcholine and appetitive behavior 1

... regions that subsequently modulate motor output. Pharmacological blockade of either glutamatergic or dopaminergic receptors within the nucleus accumbens has been shown to impair appetitive learning (Kelley, Smith-Roe, & Holahan, 1997; Smith-Roe & Kelley, 2000). Recently, intrinsic cholinergic intern ...
the mirror-neuron system - Psychology and Neuroscience
the mirror-neuron system - Psychology and Neuroscience

... of them, the effective observed and executed actions are virtually identical (strictly congruent neurons); in the remaining, the effective observed and executed actions are similar or functionally related (broadly congruent neurons). More intriguing are the properties of the communicative mirror neu ...
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Activity-dependent plasticity

A defining feature of the brain is its capacity to undergo changes based on activity-dependent functions, also called activity-dependent plasticity. Its ability to remodel itself forms the basis of the brain’s capacity to retain memories, improve motor function, and enhance comprehension and speech amongst other things. It is this trait to retain and form memories that is functionally linked to plasticity and therefore many of the functions individuals perform on a daily basis. This plasticity is the result of changed gene expression that occurs because of organized cellular mechanisms.The brain’s ability to adapt toward active functions has allowed humans to specialize in specific processes based on relative use and activity. For example, a right-handed person may perform any movement poorly with his/her left hand but continuous practice with the less dominant hand can make both hands just as able. Another example is if someone was born with a neurological disorder such as autism or had a stroke that resulted in a disorder, then they are capable of retrieving much of their lost function by practicing and “rewiring” the brain in order to incorporate these lost manners. Thanks to the pioneers within this field, many of these advances have become available to most people and many more will continue to arrive as new features of plasticity are discovered.
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