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Electrical stimulation of neural tissue to evoke behavioral responses
Electrical stimulation of neural tissue to evoke behavioral responses

... estimate how far from the electrode tip current activates neural tissue mediating behaviors such as eating (Olds, 1958), self-stimulation (Wise, 1972; Fouriezos and Wise, 1984; Milner and Laferriere, 1986), and circling behavior (Yeomans et al., 1984, 1986). The method used by Fouriezos and Wise (19 ...
- Journal of Clinical Investigation
- Journal of Clinical Investigation

... myelinolysis (CPM)' by Adams et al. (1), the pathogenesis of this disease is still not fully understood. CPM is characterized by a loss of oligodendrocytes and myelin with relatively wellpreserved neuronal cell bodies and axons in the central basis pontis. Wright et al. (2) later reported similar sy ...
322 Neuroscience I - Jordan University of Science and Technology
322 Neuroscience I - Jordan University of Science and Technology

... 1) Outline the general organization of the nervous system. 2) Describe the gross features of the human central nervous system (brain and spinal cord). 3) Discuss chemical synaptic transmission in terms of mechanisms, functions, and properties, and drugs modulating synaptic transmission. 4) Describe ...
The role of neuronal synchronization in selective attention
The role of neuronal synchronization in selective attention

... change had occurred. This finding suggests that the processing or the signalling of a sensory change is more efficient when it is handled by an area that is engaged in enhanced gamma-band synchronization [6]. Importantly, the influence of local synchronization of behavioural responses was spatiall ...
Role of the basal ganglia in conditional associative learning
Role of the basal ganglia in conditional associative learning

... The arbitrary mapping of sensory information onto action forms an important element of the intelligent behavior of primates (also called conditional associative learning). The cortico-basal ganglia-thalamo-cortical loops are thought to play a key role in such behavior. The present research was under ...
Segregation and convergence of specialised pathways in
Segregation and convergence of specialised pathways in

... At the level of cortical area V2, the various visual inputs to the cortex have reorganised to form 3 distinct channels. Anatomically these are embodied in the thick and thin dark stripes, and paler interstripes characteristic of cytochrome oxidase architecture. Do the outputs of these compartments r ...
Dynamics and Synchronization of Motifs of Neuronal Populations in the Presence
Dynamics and Synchronization of Motifs of Neuronal Populations in the Presence

... sorts of stimulus: touch, vibration, body position, temperature or pain. The receptive fields in such system comprise a limited region of the skin or the internal organs where a stimulus can elicit a neuronal response. The size of the receptive fields vary both as a function of the stimulus, and the ...
The Role of Histamine H1 , H2 and H3 Receptors on Enteric
The Role of Histamine H1 , H2 and H3 Receptors on Enteric

... Materials and Methods Male guinea pigs weighing between 250 and 350 g were used. The animals were killed by being stunned and bled via the carotid arteries. Segments (4 – 6 cm) of ileum were removed and the content of intestine flushed. The segments were placed horizontally in a bath filled with war ...
Vestibular Signals of Posterior Parietal Cortex Neurons during
Vestibular Signals of Posterior Parietal Cortex Neurons during

... sensory and motor cortices and thus could be involved in the formation of motor plans as well as abstract representations of space. We have recorded from neurons in the intraparietal sulcus, namely, the ventral and medial intraparietal areas (VIP and MIP, respectively), and analyzed their head-movem ...
Lecture 26-BasalGanglia
Lecture 26-BasalGanglia

... L-dopa exhibits a large first-pass effect Only about 1% reaches brain tissue ...
Working Memory in the Prefrontal Cortex
Working Memory in the Prefrontal Cortex

... that is necessary for complex cognitive tasks such as language comprehension, learning and reasoning. Baddeley and Logie (1999) [28] further described working memory as a mechanism that allowed humans to comprehend and mentally represent their immediate environment, retain information about their im ...
MATERNAL BEHAVIOUR IN LACTATING RATS STIMULATES c
MATERNAL BEHAVIOUR IN LACTATING RATS STIMULATES c

... behaviour that included milk letdown. Both groups of dams had a similar number of 67,000 mol. wt glutamate decarboxylaseimmunoreactive cells in each site, although the number of 67,000 mol. wt glutamate decarboxylase-immunoreactive cells per microscopic ®eld was signi®cantly greater in the caudal ve ...
Swallowing reflex and brain stem neurons activated by superior
Swallowing reflex and brain stem neurons activated by superior

... SLN stimulation at 5 Hz elicited oropharyngeal and LES but not esophageal responses and evoked c-fos expression in neurons in SolI, SolIM, SolDM, PCRt, AP, NAsc, NAl, and DMVc but not in SolCe, NAc, or DMVr. These data are consistent with the role of SolI, SolIM, SolDM, NAsc, NAl, and DMVc circuit i ...
The Inferior Parietal Lobule Is the Target of Output from the Superior
The Inferior Parietal Lobule Is the Target of Output from the Superior

... ointment was placed in the eyes. A craniotomy was performed over the parietal lobe, and the dura was incised and reflected to expose the region of interest. The cortex was kept moist by the use of warmed (37– 40°C) sterile saline throughout the entire procedure. Injection sites. One monkey received ...

 Program
and
Abstracts
from
the
Fifth
Annual
Canadian
Neuroscience
Meeting
 May
29
–
June
1
2011
 Quebec
City
Convention
Center


 Program
and
Abstracts
from
the
Fifth
Annual
Canadian
Neuroscience
Meeting
 May
29
–
June
1
2011
 Quebec
City
Convention
Center


... neurogenesis.
Intensive
investigation
has
revealed
myriad
molecular
cues
involved
in
this
form
of
 neurogenesis,
however
molecules
signaling
exclusively
for
adult
neurogenesis
are
yet
to
be
 described.
Tenascin
R
(TNR)
an
extracellular
matrix
molecule
known
to
take
part
in
neurogenesis
 is
expressed ...
PDF - Department of Molecular Biology
PDF - Department of Molecular Biology

... mutants rescued with the BAR domain (Fig. S2D–F). Consequently, Synaptojanin must have additional binding partners beyond Endophilin at synapses. Expressing mutant UNC-57 proteins lacking the SH3 domain rescued the unc-57 endocytic defects but failed to rescue the UNC-26 Synaptojanin localization de ...
Dense Core Vesicle Release: Controlling the Where as
Dense Core Vesicle Release: Controlling the Where as

... may be unique to C. elegans. However, inappropriate release of DCVs before they reach their correct release sites would be a major problem in any species and I suspect this mechanism will prove to be a common one. This also suggests that the locations of DCV release are important and that there is s ...
Lemniscal recurrent and transcortical influences on
Lemniscal recurrent and transcortical influences on

... activity. In contrast, the great majority (58/69) of the non-lemniscal neurons presented spontaneous single spike activity. Medial lemniscus stimulation induced recurrent excitation and inhibition on cuneolemniscal and nonlemniscal cells. Some non-lemniscal neurons were activated by somatosensory co ...
Amygdala-Prefrontal Synchronization Underlies Resistance to
Amygdala-Prefrontal Synchronization Underlies Resistance to

... two-way ANOVA). In both the amygdala and the dACC, responsive cells were homogeneously distributed within our recording borders (Figure S2C, p > 0.2 for all, bootstrap analysis), suggesting that they represent an activity pattern common in wide parts of these two structures. In addition, there was n ...
Spatial Responsiveness of Monkey Hippocampal Neurons to
Spatial Responsiveness of Monkey Hippocampal Neurons to

... Andersen, 1987; Goldman-Rakic, 19871, mainly via the parahippocampal cortices (PH) (Jones and Powell, 1970; Van Hoesen, 1982; Amaral, 1987; Tranel et al., 1988). Recent results indicate that the HF, and the system to which it belongs, are essential for acquisition, relation, combination, and conjunc ...
Cerebellar Unit Activity and the Movement Disruption Induced by
Cerebellar Unit Activity and the Movement Disruption Induced by

... elaboration of the motor command. According to this hypothesis cerebellum is responsible for the pre-programmed ballistic movements, while caudate nucleus is mainly concerned with the slow ramp movements. Both structures converge through the ventrolateral nucleus of thalamus upon the motor cortex, t ...
New Insights on Neural Basis of Choice
New Insights on Neural Basis of Choice

... differences. Furthermore, fMRI is not good enough to actually differentiate between all these small subregions. Some scholars will address vmPFC and OFC as different. But be careful. It may be that they talk about humans or monkeys. There is no direct homology between these areas across species. Not ...
Connectivity of the human pedunculopontine nucleus region and
Connectivity of the human pedunculopontine nucleus region and

... the principal diffusion direction corresponds to the underlying fiber direction.3,4 Therefore, by following estimates of the principal direction of diffusion it is possible to reconstruct estimated fiber pathways.9,25,37 Conventional approaches to tract tracing, however, can typically only trace pat ...
Mapping of second order olfactory neurons and ventral
Mapping of second order olfactory neurons and ventral

... system devoted to process chemosensory information is strikingly well conserved across the different species, in particular the olfactory pathways. Due to their highly specialized ability of detecting air-born molecules over long distances, plus an accessible nervous system, noctuid moths have serve ...
Neuronal Correlates for Preparatory Set Associated with Pro
Neuronal Correlates for Preparatory Set Associated with Pro

... Schmolesky et al., 1998). For comparing stimulus-related responses, we determined the mean activity in the interval 65 msec around the peak of neuronal activation in a time window from 70 to 140 msec after stimulus appearance, and the prestimulus activation in the interval 40 –50 msec after stimulus ...
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Activity-dependent plasticity

A defining feature of the brain is its capacity to undergo changes based on activity-dependent functions, also called activity-dependent plasticity. Its ability to remodel itself forms the basis of the brain’s capacity to retain memories, improve motor function, and enhance comprehension and speech amongst other things. It is this trait to retain and form memories that is functionally linked to plasticity and therefore many of the functions individuals perform on a daily basis. This plasticity is the result of changed gene expression that occurs because of organized cellular mechanisms.The brain’s ability to adapt toward active functions has allowed humans to specialize in specific processes based on relative use and activity. For example, a right-handed person may perform any movement poorly with his/her left hand but continuous practice with the less dominant hand can make both hands just as able. Another example is if someone was born with a neurological disorder such as autism or had a stroke that resulted in a disorder, then they are capable of retrieving much of their lost function by practicing and “rewiring” the brain in order to incorporate these lost manners. Thanks to the pioneers within this field, many of these advances have become available to most people and many more will continue to arrive as new features of plasticity are discovered.
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