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Pleiotropic Effects of Statins
Pleiotropic Effects of Statins

... might be increased. More clinical studies are needed in order to confirm the beneficial effects of coenzyme Q10 substitution in long-term statin therapy. The International College of Cardiology, in its scientific statement, recommended use of statins preferably in conjunction with coenzyme Q10 in or ...
A - amphetamine
A - amphetamine

... CLUB - nightclub licensed for public entertainment CLUCK - crack smoker CO-PILOT - amphetamine COASTING - under the influence of drugs COASTS TO COASTS - amphetamine COCA - cocaine COCA PASTE - an intermediate product in processing coca leaf into cocaine COCAINE BLUES - depression after extended coc ...
Cardiovascular Active Medications
Cardiovascular Active Medications

... Coronary artery and arteriolar dilation (high dose) Spasm reversal or prevention ...
Body System Adverse Effects
Body System Adverse Effects

... Copyright © 2014 by Mosby, an imprint of Elsevier Inc. ...
Urine Drug Testing Practices - Canadian Nuclear Safety Commission
Urine Drug Testing Practices - Canadian Nuclear Safety Commission

... Marijuana refers to the dried leaves, stems, seeds and/or flowers of the hemp plant or Cannabis sativa that grows worldwide in temperate and tropical climates in addition to green houses in colder climates. Cannabis contains over 400 chemical compounds including 60 cannabinoids that contain pyran an ...
Cl = Vd x 0T693
Cl = Vd x 0T693

... point because there is no limit to the amount of isoproterenol that can be given. Thus, with isoproterenol as the stimulus, the dose ratio becomes a continuous variable within the limits of toxicity of the antagonist. For endogenous stimuli, there should be a limit to the degree of beta-adrenergic s ...
Module 1. Clinical pharmacology of drugs affecting the
Module 1. Clinical pharmacology of drugs affecting the

... A. binds to the surface of T cells B. acts mainly on small, long-lived peripheral lymphocytes C. may be used in induction of immunosuppression D. may be obtained by hybridoma technique for monoclonal antibody generation E. * all of the above 37. Approximate prevalence of rheumatoid arthritis: A. * 1 ...
Nicotine and Schizophrenia
Nicotine and Schizophrenia

... • 11 tolerated the nasal spray well • Nine of 12 patients used at least 30 sprays/day 3 who are continuously abstinence still use it at 40 sprays per day, with one 10mL bottle consumed every 3 days. • The mean length of time with nasal spray treatment for all twelve patients was 255 days (range 2-81 ...
Blum et al. 2011 - Boston University
Blum et al. 2011 - Boston University

... substantiated the substance’s action as partial agonist at the mu-opioid receptor. These findings were underscored by the substance’s general pharmacological profile. Furthermore, buprenorphine was one of the first narcotic analgesics to be assessed for its abuse liability in humans. Buprenorphine w ...
Product Monograph - Habitrol® Canada Support Program
Product Monograph - Habitrol® Canada Support Program

... smoke while wearing HABITROL, adverse reactions consistent with excessive nicotine exposure may be more frequent and more pronounced. Severe and fatal adverse reactions have occurred in smokers that continued to smoke while using nicotine transdermal systems. Smokers are strongly advised to stop smo ...
Report of the Psychiatric Drug Safety Expert Advisory Panel
Report of the Psychiatric Drug Safety Expert Advisory Panel

... Panel members were unable to draw any further conclusions on the information provided in this series of case reports. Polypharmacy and concurrent poly-substance use complicated the issue in the majority of these cases. As a result, a connection between the medication and the adverse report could be ...
Differential Effects of Ethanol and Midazolam upon the Devaluation
Differential Effects of Ethanol and Midazolam upon the Devaluation

... In infant rats, low doses of ethanol have been found to attenuate the aversive representation of an unconditioned stimulus (US) as assessed through a revaluation paradigm. This may be explained by early anxiolytic properties of EtOH. The present set of experiments was aimed at analyzing possible mec ...
modafinil - Awake Institute, LLC
modafinil - Awake Institute, LLC

... other diseases, like multiple sclerosis, sleep apnea, Parkinson’s disease and depression. Modafinil’s effects are rapid (within 1-2 hours of taking the drug) and long-lasting (i.e., up to 15 hours). In controlled clinical trials, modafinil has been found to be generally well tolerated with a low inc ...
Effects of Long Acting Methylphenidate on Ghrelin Levels in Male
Effects of Long Acting Methylphenidate on Ghrelin Levels in Male

... hyperactivity disorder between the ages of 6-12 were recruited for this investigation. In addition to ghrelin levels, other laboratory findings, body mass index, body mass index percentiles, body weight-height measures and attention deficit-hyperactivity disorder symptom severity findings were analy ...
The antagonism of nondepolarizing neuromuscular
The antagonism of nondepolarizing neuromuscular

... Atropine is a tertiary amide having two actions. The most important therapeutic action is the inhibition of smooth muscles and glands innervated by the post-ganglionic cholinergic nerves. Atropine also has a central nervous system activity."' The timing of atropine administration in conjunction with ...
Pharmacokinetics
Pharmacokinetics

... single dose or 50% of usual oral dosage. Child: >12yr PO 2-3mcg/kg/day, 6-12yr PO 45mcg/kg/day; 1-5yr PO 5-6 mcg/kg/day, 6-12mos PO 6-8 mcg/kg/day, up to 6mos PO 810 mcg/kg/day – all children's as single dose am; myxedema coma- Adult: IV 200-500 mcg, may increase by 100-300mcg after 24 hr; use oral ...
Quetiapine and extrapyramidal effects
Quetiapine and extrapyramidal effects

... quetiapine, but the onset of symptoms, several weeks after starting quetiapine, makes a relation with quetiapine more plausible. Patient E also used venlafaxine since an unknown period of time as suspect medication. The dyskinesia in this patient could therefore be partly due to this drug. The outco ...
Coming Off Psychiatric Drugs
Coming Off Psychiatric Drugs

... educate people about their options if they decide to explore going off. In a culture polarized between the pro-medication propaganda of pharmaceutical companies on the one hand, and the anti-medication agenda of some activists on the other, we offer a harm reduction approach to help people make thei ...
Sleep Apnea - Viktor`s Notes for the Neurosurgery Resident
Sleep Apnea - Viktor`s Notes for the Neurosurgery Resident

... 4) MODAFINIL (Provigil®) (precise mechanism unknown; α-adrenergic agonist?) - single morning dose 100-400 mg; no effect on ability to sleep when sleep is desired; adverse effects – serious rash (incl. Stevens-Johnson syndrome); anxiety, mania, hallucinations, suicidal ideation. 5) ARMODAFINIL (Nuvig ...
What is the risk of gastrointestinal bleeding associated with selective
What is the risk of gastrointestinal bleeding associated with selective

... 23. Targownik LE. Are we worried enough about selective serotonin receptor inhibitors and upper gastrointestinal bleeding? Clin Gastroenterol Hepatol 2015;13:51-4. 24. Andrade C and Sharma E. Serotonin reuptake inhibitors and risk of abnormal bleeding. ...
Study of the interaction between 3,4- methylenedioximethamphetamine and the endocannabinoid system
Study of the interaction between 3,4- methylenedioximethamphetamine and the endocannabinoid system

... Chapter 1. Neurobiology of addiction 1.2. Habitual drug use and drug dependence. After repeated administration the effects of a drug diminish, and is necessary to increase the dose to produce the same effect. This process is known as tolerance. Tolerance may develop to some of the effects of a drug ...
HUMAN PHARMACOLOGY AYAHUASCA Director de la Tesi:
HUMAN PHARMACOLOGY AYAHUASCA Director de la Tesi:

... vernacular names. The term caapi is employed in the river Vaupés, yajé or yagé in southern Colombia, Daime or Hoasca in Brazil, natema in Ecuador and pinde along the Pacific coast of Colombia. More than 70 indigenous groups are known to employ ayahuasca, for which 42 different vernacular names have ...
The Effects of Ibuprofen on the Embryological Development of
The Effects of Ibuprofen on the Embryological Development of

... hatch, with the test determining these statistics to be very statistically significant.  However,  despite the 14 deceased embryos in medium concentration wells, resulting in an average of 6.75  surviving per well, the test determined these statistics to not be significant.   Moreover, the heart  ra ...
Professional Perspectives On Addiction Medicine
Professional Perspectives On Addiction Medicine

... challenge was to provide effective treatment and at the same time consider a known addictive substance as an ancillary treatment for certain medical conditions in patients recovering from drug addiction. According to the IOM, because of the health risks associated with smoking in general, smoked mar ...
Modification of Practice-dependent Plasticity in Human Motor Cortex
Modification of Practice-dependent Plasticity in Human Motor Cortex

... measured by the two accelerometers in the orthogonal axes of abduction--adduction and extension--flexion. All acceleration vectors were then assigned a length of 1 in a unity circle defined by the abduction--adduction and extension--flexion axes. Dispersion of the TMS-induced thumb movement vectors is ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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