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Telfast 180mg
Telfast 180mg

... Animal studies have shown that the increase in plasma levels of fexofenadine observed after coadministration of erythromycin or ketoconazole, appears to be due to an increase in gastrointestinal absorption and either a decrease in biliary excretion or gastrointestinal secretion, respectively. No int ...
THE ASPIRIN – THE FIRST DRUG OBTAINED BY SINTHESYS
THE ASPIRIN – THE FIRST DRUG OBTAINED BY SINTHESYS

... fact that determines the use in the prophylaxis of cardiovascular diseases, this being the moment of the commercial revival of the aspirin; at the European Society of Cardiology Congress, in Barcelona, 2009, were described the results of studies done in Scotland on 29000 persons with ages between 50 ...
Long-term lorazepam use in elderly psychiatric outpatients
Long-term lorazepam use in elderly psychiatric outpatients

... subjects) was associated with the magnitude of memory and psychomotor impairments following acute lorazepam administration, we modeled the outcome at 2.5 hours (i.e., time of peak effect) as a function of treatment, challenge dose and their interaction. We also explored whether the association betwe ...
Marijuana Fact Sheet - Roseville Area Schools
Marijuana Fact Sheet - Roseville Area Schools

... The Brain When people smoke marijuana for years they can suffer some pretty negative consequences. For example, because marijuana affects brain function, your ability to do complex tasks could be compromised, as well as your pursuit of academic, athletic, or other life goals that require you to be 1 ...
WORLD HEALTH ORGANIZATION ORGANISATION MONDIALE DE LA SANTE 31ST EXPERT COMMITTEE
WORLD HEALTH ORGANIZATION ORGANISATION MONDIALE DE LA SANTE 31ST EXPERT COMMITTEE

... Outline of the review procedure Since 1990, WHO’s review of psychoactive substances has been carried out in two steps, in accordance with the Revised Guidelines for the WHO Review of DependenceProducing Psychoactive Substances for International Control adopted by the Executive Board that same year. ...
Lortab® (hydrocodone bitartrate and acetaminophen tablets
Lortab® (hydrocodone bitartrate and acetaminophen tablets

... measures to reduce drug absorption. Oxygen, intravenous fluids, vasopressors, and other supportive measures should be employed as indicated. Assisted or controlled ventilation should also be considered. For hydrocodone overdose, primary attention should be given to the reestablishment of adequate re ...
Prescribing information Lortab® (USA)September-2014
Prescribing information Lortab® (USA)September-2014

... measures to reduce drug absorption. Oxygen, intravenous fluids, vasopressors, and other supportive measures should be employed as indicated. Assisted or controlled ventilation should also be considered. For hydrocodone overdose, primary attention should be given to the reestablishment of adequate re ...
Hypoglossal Nerve Response to 5-HT3 Drugs Injected into the XII
Hypoglossal Nerve Response to 5-HT3 Drugs Injected into the XII

... site. Sites were regarded appropriate when 5-HT injection produced at least a 25% increase in activity (Fig. 1A). In two animals, glutamate (1 mM L-glutamic acid monosodium salt, Sigma), rather than 5-HT, was used to verify proper placement of the pipette. Occasionally, when the first injection of 5 ...
A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine
A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine

... intraperitoneal administration of MFZ 10-7 inhibited intravenous cocaine self-administration, cocaine-induced reinstatement of drug-seeking behavior and cocaine-associated cue-induced cocaine-seeking behavior in rats. Although MFZ 10-7 and MTEP lowered the rate of oral sucrose self-administration, t ...
New pharmacological technologies in the clinical management of
New pharmacological technologies in the clinical management of

... Buprenorphine adverse effects • The most severe and serious adverse reaction associated with opioid use in general is respiratory depression, the mechanism behind fatal overdose. • Buprenorphine behaves differently than other opioids in this respect, as it shows a ceiling effect for respiratory dep ...
ANALGESIC AND ANTHELMINTIC ACTIVITY OF VARIOUS EXTRACTS OF ANDROGRAPHIS  Research Article
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Intra-Ventral Tegmental Area Injection of Rat Cocaine and

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Pain and Opioid (Narcotic) Analgesics
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... regulate the continuing afferent input. But pain can occur without nociception (some neuralgias). Pain is a psychological state; though most types of pain have a physical cause. 3. Suffering is a consequence of pain and lack of understanding by patients what the meaning of pain is. Suffering compris ...
All roads lead to Rome, but which one is the best?
All roads lead to Rome, but which one is the best?

... About 1% of the population is affected by Autism Spectrum Disorder (ASD). The main symptoms of ASD are poor communication, poor social interactions and abnormal behavior. The last decade, the general conception about ASD switched from being a developmental disorder to being a treatable disorder late ...
Wellbutrin/Wellbutrin-SR/ Wellbutrin
Wellbutrin/Wellbutrin-SR/ Wellbutrin

... Most cases of major depression can be treated successfully, usually with medication, psychotherapy, or both. The combination of psychotherapy and antidepressants is very effective in treating moderate to severe depression. The medications improve mood, sleep, energy, and appetite, while therapy stre ...
Chapter - 6 Evaluation ofCNS depressant and anticonvulsant
Chapter - 6 Evaluation ofCNS depressant and anticonvulsant

... neurotransmitters. The neuromodulators like prostaglandins (PGs), purines and neuropeptides interact with their recognition sites i.e. receptors and regulate the function o f CNS (Seth, 2005). 6.1.2. D rugs acting on central nervous system Drugs acting on CNS were first discovered by the primitive h ...
New Jersey Department of Children and Families Psychotropic Medication Policy
New Jersey Department of Children and Families Psychotropic Medication Policy

... and the resources of the community. A treatment plan should include appropriate behavior planning, monitoring of symptoms and medication effects, and on-going communication between the prescriber and the child, parents, resource family, caseworker, therapist, pediatrician and other members of the ch ...
Antiplatelet drugs compared - Consumer Reports Best Buy Drugs
Antiplatelet drugs compared - Consumer Reports Best Buy Drugs

... Aspirin is used to relieve pain and headaches and reduce fevers, but doctors also prescribe it to reduce the risk of heart attack and stroke in people who have heart disease and people with an elevated risk of heart attack or stroke—such as those who smoke, have high blood pressure, high cholestero ...
Hypnotics in clinical practice - South West Yorkshire Partnership
Hypnotics in clinical practice - South West Yorkshire Partnership

...  NICE says use a hypnotic with a short half-life with the lowest cost per dose o Temazepam does have a low acquisition cost but as it is administered as a CD for in-patients this increases the actual cost to the trust. It is not recommended due to its previous history as a drug of abuse. o Lormetaz ...
Barbiturate
Barbiturate

... and hypnotics. Today, benzodiazepines have largely supplanted them for these purposes, because benzodiazepines have less potential for lethal overdoses Barbiturates are classified as ultrashort-, short-, intermediate-, and long-acting, depending on how quickly they act and how long their effects las ...
INTERACTION BETWEEN GRAPEFRUIT JUICE AND DRUGS*
INTERACTION BETWEEN GRAPEFRUIT JUICE AND DRUGS*

... juice selectively inhibits a molecular species of CYP3A in the small intestine and raises the bioavailability of felodipine. Orange juice is not associated with the inhibitory actions described above. Because the expression of a molecular species of CYP3A is reduced by grapefruit juice, it is eviden ...
Data Sheet
Data Sheet

... especially high in the bronchial tree. The absorption of lignocaine jelly from the nasopharynx is variable but usually lower than with other lignocaine products. Following instillation in urethra and bladder, adsorption is low. Lignocaine jelly should be used with caution in patients with traumatise ...
Chapter 8 lesson 1 - ROP Pharmacology for Health Care
Chapter 8 lesson 1 - ROP Pharmacology for Health Care

... All Rights Reserved ...
Evaluation for Zero-order Controlled Release Preparations of
Evaluation for Zero-order Controlled Release Preparations of

... systems which are developed to obtain a stronger therapeutic eŠect from agents that have already been marketed as well as for use with novel compounds. Oral controlled-release preparations are a representative type of drug delivery system. Advanced pharmaceutical technology is necessary for controll ...
The a7 Nicotinic Receptor Agonist ABT-107 Decreases L
The a7 Nicotinic Receptor Agonist ABT-107 Decreases L

... nAChR–selective drugs may function via a final common mechanism to reduce LIDs. The present results suggest that drugs targeting either a7 or b2 nAChRs may be useful as antidyskinetic agents in Parkinson’s disease. ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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