
Marijuana Information marijuana
... World Health Organization ranks the United States first among 17 European and North American countries for prevalence of marijuana use. And more users start every day. In 2008, an estimated 2.2 million Americans used marijuana for the first time; greater than half were under age 18. The use of marij ...
... World Health Organization ranks the United States first among 17 European and North American countries for prevalence of marijuana use. And more users start every day. In 2008, an estimated 2.2 million Americans used marijuana for the first time; greater than half were under age 18. The use of marij ...
Beta adrenergic influence on oesophageal peristalsis
... From the Division of Gastroenterology, Department of Medicine II, Sahlgren's Hospital, University of Goteborg, Sweden ...
... From the Division of Gastroenterology, Department of Medicine II, Sahlgren's Hospital, University of Goteborg, Sweden ...
Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent
... experience anxiety or dissociative symptoms [67] or improved sleep quality, as assessed by standardized rating scales. We did not include in this review studies on cannabis extracts or CBD-rich extracts, as the other several compounds may have multiple interactions with CBD. However, some clinical t ...
... experience anxiety or dissociative symptoms [67] or improved sleep quality, as assessed by standardized rating scales. We did not include in this review studies on cannabis extracts or CBD-rich extracts, as the other several compounds may have multiple interactions with CBD. However, some clinical t ...
Short-Term Fasting Alters Cytochrome P450–Mediated Drug
... can be explained by the altered activity of nuclear transcription factors. The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (Klein et al., 1993) serve as xenosensors, which regulate the activity of many of the drug-metabolizing P450 enzymes in animals (Hernandez e ...
... can be explained by the altered activity of nuclear transcription factors. The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (Klein et al., 1993) serve as xenosensors, which regulate the activity of many of the drug-metabolizing P450 enzymes in animals (Hernandez e ...
Dopamine-lnduced Alterations In Left Ventricular Performance
... Fourteen mongrel dogs weighing 16 to 31 kg were anesthetized with 40 to 70 ml of chloralose (1.6%) and urethane (16%) 15 minutes after intramuscular administration of 3.0 mg/kg of morphine sulfate. Additional 5 to 10 ml supplements of the chloralose and urethane solution were administered during the ...
... Fourteen mongrel dogs weighing 16 to 31 kg were anesthetized with 40 to 70 ml of chloralose (1.6%) and urethane (16%) 15 minutes after intramuscular administration of 3.0 mg/kg of morphine sulfate. Additional 5 to 10 ml supplements of the chloralose and urethane solution were administered during the ...
Pharmacotherapy for Smoking Cessation
... Patient factors? The smoker’s level of dependence on nicotine influences NRT effectiveness heavy smokers (>30 cigarettes/day) benefit from higher doses of nicotine replacement e.g. 4mg gum vs 2mg or combinations of NRT limited evidence of NRT effectiveness in those who smoke less than 10-15 ciga ...
... Patient factors? The smoker’s level of dependence on nicotine influences NRT effectiveness heavy smokers (>30 cigarettes/day) benefit from higher doses of nicotine replacement e.g. 4mg gum vs 2mg or combinations of NRT limited evidence of NRT effectiveness in those who smoke less than 10-15 ciga ...
Recent changes in Europe`s MDMA/ecstasy market
... production is destined for internal markets, with Germany and the United Kingdom being the most common destinations. There is no evidence of MDMA being imported into the European Union (EU). Assessing recent trends in MDMA seizures is difficult due to the absence of data from some countries that are ...
... production is destined for internal markets, with Germany and the United Kingdom being the most common destinations. There is no evidence of MDMA being imported into the European Union (EU). Assessing recent trends in MDMA seizures is difficult due to the absence of data from some countries that are ...
Angiotensin II Increases Norepinephrine Release
... the driving stimulus, ie, during the myocardial refractory period, through two parallel platinum electrodes (1.5 cm long, 0.5 mm in diameter, 1 cm apart, one on each side of the muscle). For 1 hour, only myocardial driving stimulation was used, and the bathing solution was changed every 10 minutes t ...
... the driving stimulus, ie, during the myocardial refractory period, through two parallel platinum electrodes (1.5 cm long, 0.5 mm in diameter, 1 cm apart, one on each side of the muscle). For 1 hour, only myocardial driving stimulation was used, and the bathing solution was changed every 10 minutes t ...
Antihistamines - Consumer Health Choices
... Studies have found that some people who get prescriptions for allergy medicine do not actually have allergies. If you are taking antihistamines or other allergy medicine regularly, you should consult a doctor to make sure that you do have allergies, and that the medication is appropriate for your co ...
... Studies have found that some people who get prescriptions for allergy medicine do not actually have allergies. If you are taking antihistamines or other allergy medicine regularly, you should consult a doctor to make sure that you do have allergies, and that the medication is appropriate for your co ...
Synergistic interactions of SQ109, a new
... are continued, usually daily, for an additional 4–7 months (continuation phase). Failure to provide adequate drugs to patients, or failure of patients to complete the long-term therapy with all four drugs, results in the emergence of drug-resistant M. tuberculosis. In order to control the current TB ...
... are continued, usually daily, for an additional 4–7 months (continuation phase). Failure to provide adequate drugs to patients, or failure of patients to complete the long-term therapy with all four drugs, results in the emergence of drug-resistant M. tuberculosis. In order to control the current TB ...
PR OZA C - Family Guardian
... research the theory behind this group of drugs is invalid. Known as serotonin reuptake inhibitors, these drugs are designed to interfere with serotonin metabolism, thereby increasing brain levels of this neurotransmitter, Yet for three decades researchers have been intensely interested in serotonin ...
... research the theory behind this group of drugs is invalid. Known as serotonin reuptake inhibitors, these drugs are designed to interfere with serotonin metabolism, thereby increasing brain levels of this neurotransmitter, Yet for three decades researchers have been intensely interested in serotonin ...
Dopamina. Monografia del farmaco.
... Dopamine's onset of action occurs within 5 minutes of intravenous administration, and with dopamine's plasma half-life of about 2 minutes, the duration of action is less than 10 minutes. However, if monoamine oxidase (MAO) inhibitors are present, the duration may increase to 1 hour. The drug is wide ...
... Dopamine's onset of action occurs within 5 minutes of intravenous administration, and with dopamine's plasma half-life of about 2 minutes, the duration of action is less than 10 minutes. However, if monoamine oxidase (MAO) inhibitors are present, the duration may increase to 1 hour. The drug is wide ...
The placebo effect in Parkinson`s disease
... Using PET with [11C]raclopride (RAC), we found that patients with Parkinson’s disease release substantial amounts of dopamine in the dorsal striatum (i.e. caudate and putamen) in response to subcutaneous injection of saline (Fig. 1) [50]. In this paradigm, changes in RAC binding between baseline and ...
... Using PET with [11C]raclopride (RAC), we found that patients with Parkinson’s disease release substantial amounts of dopamine in the dorsal striatum (i.e. caudate and putamen) in response to subcutaneous injection of saline (Fig. 1) [50]. In this paradigm, changes in RAC binding between baseline and ...
Document
... 1. Insufficient response to conventional drugs 2. Side effects from conventional drugs 3. Rejection of conventional drug treatment. 4. Allergy to one or two allergens only Types: Systemic injection, intra-nasal, sublingual ...
... 1. Insufficient response to conventional drugs 2. Side effects from conventional drugs 3. Rejection of conventional drug treatment. 4. Allergy to one or two allergens only Types: Systemic injection, intra-nasal, sublingual ...
Pain Management in Older Adults www.rxfiles.ca
... Communicate (PACSLAC) – monitor, over time, behaviours that may be pain related (e.g. activity, agitation, sleep) • Discuss findings & observations with family to assess what has been “normal” for that individual. • It is often important to differentiate psychological/emotional suffering – voice ...
... Communicate (PACSLAC) – monitor, over time, behaviours that may be pain related (e.g. activity, agitation, sleep) • Discuss findings & observations with family to assess what has been “normal” for that individual. • It is often important to differentiate psychological/emotional suffering – voice ...
HIGHLIGHTS OF PRESCRIBING INFORMATION --------------------------WARNINGS AND PRECAUTIONS---------------------------
... CNS stimulants (amphetamines and methylphenidate-containing products) have a high potential for abuse and dependence. Assess the risk of abuse prior to prescribing, and monitor for signs of abuse and dependence while on therapy [see Drug Abuse and Dependence (9.2, 9.3)]. 5.2 Serious Cardiovascular R ...
... CNS stimulants (amphetamines and methylphenidate-containing products) have a high potential for abuse and dependence. Assess the risk of abuse prior to prescribing, and monitor for signs of abuse and dependence while on therapy [see Drug Abuse and Dependence (9.2, 9.3)]. 5.2 Serious Cardiovascular R ...
PRESCRIBING INFORMATION Entex LA Pseudoephedrine
... Nursing Mothers: It is not known whether the drugs in Entex LA are excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the produ ...
... Nursing Mothers: It is not known whether the drugs in Entex LA are excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the produ ...
Immediate time course of drug effect
... explains the time course of effects after a drug dose. The science linking dose and concentration is pharmacokinetics. The two main pharmacokinetic properties of a drug are clearance (CL) and volume of distribution (V). The science linking concentration and effect is pharmacodynamics. The two main p ...
... explains the time course of effects after a drug dose. The science linking dose and concentration is pharmacokinetics. The two main pharmacokinetic properties of a drug are clearance (CL) and volume of distribution (V). The science linking concentration and effect is pharmacodynamics. The two main p ...
Alcohol and Other Drugs: A Handbook for Health Professionals
... expanded and progressed in many ways. Hence, this new version covers expanded territory (such as polydrug use and coexisting mental health problems) and newer topic areas (such as gambling). Effort was directed at producing a resource document that was both user-friendly and also captured up-to-date ...
... expanded and progressed in many ways. Hence, this new version covers expanded territory (such as polydrug use and coexisting mental health problems) and newer topic areas (such as gambling). Effort was directed at producing a resource document that was both user-friendly and also captured up-to-date ...
American Geriatrics Society 2015 Updated Beers Criteria for
... from inappropriate care. The panel considered and vigorously discussed both roles during deliberations. The panel’s review of evidence at times identified subgroups of individuals who should be exempt from a given criterion or to whom a specific criterion should apply. Such a criterion may not be ea ...
... from inappropriate care. The panel considered and vigorously discussed both roles during deliberations. The panel’s review of evidence at times identified subgroups of individuals who should be exempt from a given criterion or to whom a specific criterion should apply. Such a criterion may not be ea ...
Newer Antihistamines
... commonly used in childhood, their central nervous system (CNS) effects have not been well-documented in young subjects. We hypothesized that diphenhydramine and hydroxyzine would affect CNS function adversely in this population. Our objective was to evaluate the effects of these medications on centr ...
... commonly used in childhood, their central nervous system (CNS) effects have not been well-documented in young subjects. We hypothesized that diphenhydramine and hydroxyzine would affect CNS function adversely in this population. Our objective was to evaluate the effects of these medications on centr ...
Antidepressant Drugs - Vendor Drug Program
... severe depression, treatment-resistant depression (TRD), and moderate anxiety/agitation/depression. Maximum recommended daily doses for antidepressant drugs in adults, including the elderly population, are summarized in Tables 1 and 2. Maximum recommended dosages for antidepressant combination thera ...
... severe depression, treatment-resistant depression (TRD), and moderate anxiety/agitation/depression. Maximum recommended daily doses for antidepressant drugs in adults, including the elderly population, are summarized in Tables 1 and 2. Maximum recommended dosages for antidepressant combination thera ...
A molecular basis of the therapeutic and psychoactive
... ‘‘Although some differences exist in the interactions with specific proteins, the fact remains that psychoactive cannabinoids affect a broad range of membrane-bound receptors, which supports the concept of a direct influence on the membrane lipid bilayer, rather than an embedded receptor specific fo ...
... ‘‘Although some differences exist in the interactions with specific proteins, the fact remains that psychoactive cannabinoids affect a broad range of membrane-bound receptors, which supports the concept of a direct influence on the membrane lipid bilayer, rather than an embedded receptor specific fo ...
Testing and Comparison of Non-Opioid Analgesics in Amphibians
... animals were euthanized by an overdose of tricaine methylsulfonate (MS-222, Sigma-Aldrich) at the end of the study. Algesiometric measurement. The nociceptive, or pain, threshold in amphibians can be estimated by using the acetic acid test (34). Briefly, 11 serial dilutions of glacial acetic acid ar ...
... animals were euthanized by an overdose of tricaine methylsulfonate (MS-222, Sigma-Aldrich) at the end of the study. Algesiometric measurement. The nociceptive, or pain, threshold in amphibians can be estimated by using the acetic acid test (34). Briefly, 11 serial dilutions of glacial acetic acid ar ...
COMMITTEE OPINION Committee on Gynecologic Practice Number 484 • April 2011
... because they are not considered controlled substances. Some medications, such as dehydroepiandrosterone sulfate, are considered dietary supplements and can be purchased over the counter. These preparations can have serious risks when used for nonmedical purposes, some of which may be similar to thos ...
... because they are not considered controlled substances. Some medications, such as dehydroepiandrosterone sulfate, are considered dietary supplements and can be purchased over the counter. These preparations can have serious risks when used for nonmedical purposes, some of which may be similar to thos ...
Stimulant

Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.