Slide - Smith Lab
... Retention of T cells with specificity to ocular antigens due to Weak negative selection in individuals with particular HLA types Previous infection or trauma primed for ocular antigens in an ...
... Retention of T cells with specificity to ocular antigens due to Weak negative selection in individuals with particular HLA types Previous infection or trauma primed for ocular antigens in an ...
Kuby Immunology 6/e - Dr. Jennifer Capers, PhD
... Bind to BOTH the TCR and MHC Can cause over-activation Overproduction of TH-cell cytokines, leading to systemic toxicity ...
... Bind to BOTH the TCR and MHC Can cause over-activation Overproduction of TH-cell cytokines, leading to systemic toxicity ...
Immunology & History of HIV
... Early history of HIV •Two samples from Kinshasa, Congo, 1959 and 1960 ...
... Early history of HIV •Two samples from Kinshasa, Congo, 1959 and 1960 ...
lec #1 done by Leen AbdelFattah / Slides #1
... maturation , it express different receptors on its surface at different stages, to specify its location we depend on the surface receptors ,BCR: B cell receptor, which are the immunoglobins on its surface. BCR could be IgM or IgD Function of the BCR: recognition of foreign substances. But they can b ...
... maturation , it express different receptors on its surface at different stages, to specify its location we depend on the surface receptors ,BCR: B cell receptor, which are the immunoglobins on its surface. BCR could be IgM or IgD Function of the BCR: recognition of foreign substances. But they can b ...
Autoimmunity Autoimmunity Targets of Autoimmunity
... – T cells interact strongly with self MHC and self peptides are killed – B cells that have anti-self antibodies are killed ...
... – T cells interact strongly with self MHC and self peptides are killed – B cells that have anti-self antibodies are killed ...
Lecture #23 - Suraj @ LUMS
... • The nonspecific (innate) responses are the first line of defense - block the entry and spread of disease-causing agents. • Highly specific (adaptive) responses are the second line of defense and are tailored to an individual threat. • Antibody-mediated and cell-mediated responses are two types of ...
... • The nonspecific (innate) responses are the first line of defense - block the entry and spread of disease-causing agents. • Highly specific (adaptive) responses are the second line of defense and are tailored to an individual threat. • Antibody-mediated and cell-mediated responses are two types of ...
Immune Worksheet Session 27- 4/7/11
... 2) In positive selection, what happens if the T cell recognizes the self-MHC? In positive selection, what happens if the T cell fails to recognize the self-MHC? 3) In negative selection, what happens if the T cell recognizes the self-antigen? In negative selection, what happens if the T cell fails t ...
... 2) In positive selection, what happens if the T cell recognizes the self-MHC? In positive selection, what happens if the T cell fails to recognize the self-MHC? 3) In negative selection, what happens if the T cell recognizes the self-antigen? In negative selection, what happens if the T cell fails t ...
Nonspecific Immunity
... Delayed hypersensitivity T • Allergic reactions, organ rejection – Suppressor T – Antigen Presenting Cells (APC) • MHC-I • MHC-II ...
... Delayed hypersensitivity T • Allergic reactions, organ rejection – Suppressor T – Antigen Presenting Cells (APC) • MHC-I • MHC-II ...
Document
... • The nature of the disease is determined by the type of dominant immune response – Th1 response: inflammation, autoantibody production; autoimmune diseases – Th2 response: IgE+eosinophil-mediated inflammation; allergic reactions – Th17 response: acute (and chronic?) inflammation; increasingly recog ...
... • The nature of the disease is determined by the type of dominant immune response – Th1 response: inflammation, autoantibody production; autoimmune diseases – Th2 response: IgE+eosinophil-mediated inflammation; allergic reactions – Th17 response: acute (and chronic?) inflammation; increasingly recog ...
practice
... 2. Lymphocytes secrete antibodies. 3. Antigenic determinants from pathogen bind to antigen receptors on T helper lymphocytes. 4. Lymphocytes specific to antigenic determinants from pathogen become numerous. 5. Only memory cells remain to fight future potential infections. A) B) C) D) ...
... 2. Lymphocytes secrete antibodies. 3. Antigenic determinants from pathogen bind to antigen receptors on T helper lymphocytes. 4. Lymphocytes specific to antigenic determinants from pathogen become numerous. 5. Only memory cells remain to fight future potential infections. A) B) C) D) ...
Cell theory
... Robert Hooke- was the first person to see a single cell in a microscope. It was four walls. It reminded him of a monastery room-referred to as a cell. So he called it “the cell”. Antoine Leeuwenhoek- Saw water in a microscope and discovered that tiny microscopic bacteria do exist in water. Matt Schl ...
... Robert Hooke- was the first person to see a single cell in a microscope. It was four walls. It reminded him of a monastery room-referred to as a cell. So he called it “the cell”. Antoine Leeuwenhoek- Saw water in a microscope and discovered that tiny microscopic bacteria do exist in water. Matt Schl ...
AUTOIMMUNE ENDOCRINE DISEASES
... There are multiple possible etiologies of autoimmune endocrinopathies, but regardless of the precise cause, there are two fundamentally different autoimmune mechanisms causing endocrine disease in the first 2 vignettes. In the patient with hyperthyroidism, a functional agonistic autoantibody, either ...
... There are multiple possible etiologies of autoimmune endocrinopathies, but regardless of the precise cause, there are two fundamentally different autoimmune mechanisms causing endocrine disease in the first 2 vignettes. In the patient with hyperthyroidism, a functional agonistic autoantibody, either ...
bios 1030. week 11. session 3. hannah reckman. password= bronchi
... c) Maintain our blood volume by collecting excess fluid that will leak out of capillaries when they are dilated and leaky because of histamines. d) Consists only of lymph nodes that hold our B and T cells. 5) Your complement system is being activated by antibodies in an attempt to get rid of an anti ...
... c) Maintain our blood volume by collecting excess fluid that will leak out of capillaries when they are dilated and leaky because of histamines. d) Consists only of lymph nodes that hold our B and T cells. 5) Your complement system is being activated by antibodies in an attempt to get rid of an anti ...
IMMUNOLOGY 2010™ Poster Symposia Schedule
... Disease Cytokines II: Immunomodulatory Cytokines Effector Cells and Tissue Damage in Autoimmunity Host Defense: Innate Immune Receptors and Signal Transduction Immune Regulation of Host Immunity during Viral Infection Immune System Regulation iTreg, Th17, and CD4 CTL Differentiation Leukocyte Activa ...
... Disease Cytokines II: Immunomodulatory Cytokines Effector Cells and Tissue Damage in Autoimmunity Host Defense: Innate Immune Receptors and Signal Transduction Immune Regulation of Host Immunity during Viral Infection Immune System Regulation iTreg, Th17, and CD4 CTL Differentiation Leukocyte Activa ...
Immune Checkpoint Blockade in Cancer Therapy: New Insights and
... However, there is also evidence that anti-CTLA-4 has to engage the target on both effector (Teff) and regulatory (Treg) T cells. Thus anti-CTLA-4 exerts its anti-tumor effects by multiple mechanisms. PD-1, another checkpoint, recruits a phosphatase and seems to interfere with T cell antigen receptor ...
... However, there is also evidence that anti-CTLA-4 has to engage the target on both effector (Teff) and regulatory (Treg) T cells. Thus anti-CTLA-4 exerts its anti-tumor effects by multiple mechanisms. PD-1, another checkpoint, recruits a phosphatase and seems to interfere with T cell antigen receptor ...
Master Answers for the Autoimmune Disease Small group Master
... There are multiple possible etiologies of autoimmune endocrinopathies, but regardless of the precise cause, there are two fundamentally different autoimmune mechanisms causing endocrine disease in the first 2 vignettes. In the patient with hyperthyroidism, a functional agonistic autoantibody, either ...
... There are multiple possible etiologies of autoimmune endocrinopathies, but regardless of the precise cause, there are two fundamentally different autoimmune mechanisms causing endocrine disease in the first 2 vignettes. In the patient with hyperthyroidism, a functional agonistic autoantibody, either ...
F13Lect21Cancer
... Translocation (9, 22) creates the fusion protein of BCR (function unknown) and Abl (cytoplasmic protein kinase regulating actin polumerization). BCR-Abl is a protein kinase with broad target specificity including JAK 2 and STAT5. ...
... Translocation (9, 22) creates the fusion protein of BCR (function unknown) and Abl (cytoplasmic protein kinase regulating actin polumerization). BCR-Abl is a protein kinase with broad target specificity including JAK 2 and STAT5. ...