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Download 79th WPI-IIIS Seminar - International Institute for Integrative Sleep
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Transcript
The presence of DNA and aberrant RNA in the cytoplasm is a danger signal that alerts the host immune system to eliminate microbial infections, but inappropriate activation of these pathways can also lead to autoimmune diseases such as lupus. My talk will focus on our recent work on the discovery of a new innate immune sensor for cytosolic DNA, and a novel second messenger that triggers the production of type-I interferons and other inflammatory cytokines. I will also discuss the roles of this pathway in autoimmune diseases and cancer immunotherapy. Speaker: Dr. Zhijian Chen Center for Genetics of Host Defense UT Southwestern Medical Center / HHMI USA Date: Monday, June 13, 2016 Time: 12:00 - 13:00 Venue: 1F Auditorium, IIIS Building University of Tsukuba ☆Light refreshments will be served. Contact: International Institute for Integrative Sleep Medicine Phone: 029-853-8080 (ext.8080)
