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Biologist ___________________________ Date ______________ 35-4 Immune System Disorders – Reading Guide When the Immune System “Misfires” For Questions 1–5, complete each statement by writing the correct word or words. 1. An overreaction of the immune system to antigens of pollen and other harmless substances is called a(n) . 2. Sneezing, a runny nose, and watery eyes are symptoms of the system. 3. Drugs called counteract the effects of response in the respiratory produced by mast cells. 4. A dangerous condition that affects the respiratory system and can be caused by allergies is called . 5. Examples of triggers for allergic reactions include tobacco smoke, pollution, molds, and pet dander. 6. What is an autoimmune disease? 7. Describe the advantage and disadvantage of treating an autoimmune illness such as lupus. 8. Complete the table about autoimmune diseases. Autoimmune Diseases Autoimmune Disease Organ or Tissue That Is Attacked Type I diabetes Connective tissues around the joints Lupus HIV and AIDS 9. What does AIDS stand for? 10. What is the term that describes diseases that attack people with a weakened immune system? 11. List four body fluids that can transmit AIDS. A. B. C. D. 12. What behaviors prevent people from being infected with HIV? 13. Why is curing HIV infection so challenging? Explain your answer. 14. Complete the flowchart that summarizes the HIV infection process. HIV attaches to host cell membranes with specific surface molecules. Viral DNA enters nucleus, attaches to host DNA, and makes viral RNA. New viruses bud off of host cell membrane and infect more cells. 15. What is the key difference between an immunodeficiency disease and an autoimmune disease? Provide an example of both types of disease in your response.