Linköping University Post Print In vitro priming recapitulates in vivo HIV-1
... Both infectious and AT-2 inactivated HIV-1 can be used as antigenic sources by DCs to prime HIV-specific T cells from CD45RA+ naı̈ve T cells The ability of DCs to prime HIV-specific responses in vitro has previously been established by several studies using various antigen preparations, e.g. peptide ...
... Both infectious and AT-2 inactivated HIV-1 can be used as antigenic sources by DCs to prime HIV-specific T cells from CD45RA+ naı̈ve T cells The ability of DCs to prime HIV-specific responses in vitro has previously been established by several studies using various antigen preparations, e.g. peptide ...
Z. Yuan, X. Fan, B. Staitieh, et al. HIV
... gp120 induces TREM-1 expression in macrophages and confers anti-apoptotic attributes.NF-κB p65 silencing identified that these proteins induce TREM-1 in p65-dependent manner. TREM-1 silencing in macrophages exposed to HIV-related proteins led to increased caspase 3 activation and reduced Bcl-2 expre ...
... gp120 induces TREM-1 expression in macrophages and confers anti-apoptotic attributes.NF-κB p65 silencing identified that these proteins induce TREM-1 in p65-dependent manner. TREM-1 silencing in macrophages exposed to HIV-related proteins led to increased caspase 3 activation and reduced Bcl-2 expre ...
Altered immunological reactivity in alveolar R.B Gallagher*,
... and accessory function did not correlate with pulmonary T cells. The immunological competence of pulmonary macrophages is currently the subject of some controversy. We have found lavage macrophages to be significantly poorer accessory cells than peripheral blood monocytes. This is in agreement with ...
... and accessory function did not correlate with pulmonary T cells. The immunological competence of pulmonary macrophages is currently the subject of some controversy. We have found lavage macrophages to be significantly poorer accessory cells than peripheral blood monocytes. This is in agreement with ...
a PDF of this article
... these basic findings. It seems likely that the TLR system links diseases from infection to arthritis to allergy, promising a broad spectrum of therapeutic benefits. For example, Beutler points to two novel approaches for combating infectious diseases. First, he says, blocking TLR signaling with LPS ...
... these basic findings. It seems likely that the TLR system links diseases from infection to arthritis to allergy, promising a broad spectrum of therapeutic benefits. For example, Beutler points to two novel approaches for combating infectious diseases. First, he says, blocking TLR signaling with LPS ...
Abstract book - Belgian Society for Microbiology
... animals with MCF and healthy controls were analyzed by microarray. Two regions on the viral genome were transcriptionally active, one encoding a homologue to the latency-associated nuclear antigen (ORF73) of other gamma herpesviruses, the other with no predicted open reading frame. On the host’s sid ...
... animals with MCF and healthy controls were analyzed by microarray. Two regions on the viral genome were transcriptionally active, one encoding a homologue to the latency-associated nuclear antigen (ORF73) of other gamma herpesviruses, the other with no predicted open reading frame. On the host’s sid ...
Sex hormone modulation of human uterine epithelial cell immune
... glandular epithelium, and tissues derived from women in late secretory phase secreted more SLPI than tissues obtained from women in the proliferative phase (King and others 2000; Fleming and others 2003). The expression of endometrial SLPI was upregulated by estrogen in the rat (Chen and others 2004 ...
... glandular epithelium, and tissues derived from women in late secretory phase secreted more SLPI than tissues obtained from women in the proliferative phase (King and others 2000; Fleming and others 2003). The expression of endometrial SLPI was upregulated by estrogen in the rat (Chen and others 2004 ...
Comparative analysis of the acute response of the trout, O. mykiss
... time point (b) Differentially expressed genes (p < 0.01; FDR < 0.05) with a 2-fold increase in expression levels are shown for each treatment and time point. ...
... time point (b) Differentially expressed genes (p < 0.01; FDR < 0.05) with a 2-fold increase in expression levels are shown for each treatment and time point. ...
Synergic effect of the use of anthrax and dental microbial plaque
... objective of obtaining the synergetic effect. - Is possible to rise the effects of anthrax toxins with simple addiction of cytokines (IL-1, TNF…), chemocynes (MIP, IP-10, MCP-1...) and growth factors ( ERGF…), LPS at concentration greater than 100 ng/mL, ON, PGs etc… - In my experience with dental p ...
... objective of obtaining the synergetic effect. - Is possible to rise the effects of anthrax toxins with simple addiction of cytokines (IL-1, TNF…), chemocynes (MIP, IP-10, MCP-1...) and growth factors ( ERGF…), LPS at concentration greater than 100 ng/mL, ON, PGs etc… - In my experience with dental p ...
A metabolomic analysis of the mammalian gut microbiota
... The gut microbiota confers resistance to colonization by pathogens Antibiotic treatment increases mouse susceptibility to Salmonella infection ...
... The gut microbiota confers resistance to colonization by pathogens Antibiotic treatment increases mouse susceptibility to Salmonella infection ...
Pivotal Role of the B7:CD28 Pathway in
... serve as APCs. In the peripheral blood, for example, dendritic cells, activated B cells, and monocytes can present antigen, whereas, in skin, keratinocytes and Langherans cells serve this function. Because the major function of peripheral blood dendritic cells, activated B cells, and activated macro ...
... serve as APCs. In the peripheral blood, for example, dendritic cells, activated B cells, and monocytes can present antigen, whereas, in skin, keratinocytes and Langherans cells serve this function. Because the major function of peripheral blood dendritic cells, activated B cells, and activated macro ...
Adverse Reactions to Blood Products
... • if delayed (3-14 days after transfusion): – investigate for delayed hemolytic transfusion reaction (DHTR) • usually non-ABO antibodies that took time to “resurge” after the offending red cell transfusion • may not have symptoms of hemolysis (fever, hemoglobinuria) ...
... • if delayed (3-14 days after transfusion): – investigate for delayed hemolytic transfusion reaction (DHTR) • usually non-ABO antibodies that took time to “resurge” after the offending red cell transfusion • may not have symptoms of hemolysis (fever, hemoglobinuria) ...
Chapter 3
... • Differs from nonspecific defense mechanisms – specificity----recognize self & non-self – memory----2nd encounter produces even more vigorous response • Antigens are substances recognized as foreign by the immune responses. • The branch of science that deals with the responses of the body when chal ...
... • Differs from nonspecific defense mechanisms – specificity----recognize self & non-self – memory----2nd encounter produces even more vigorous response • Antigens are substances recognized as foreign by the immune responses. • The branch of science that deals with the responses of the body when chal ...
Experimental Biology and Medicine
... There are also several reports of mushrooms containing more than one polysaccharide with antitumor activity (1). An interesting example is A. blazei. It contains an antitumor glucan with a b-(1!6) backbone (17), which differs from the b-(1!3) backbone with 1!6 branches shared by many other antitumor ...
... There are also several reports of mushrooms containing more than one polysaccharide with antitumor activity (1). An interesting example is A. blazei. It contains an antitumor glucan with a b-(1!6) backbone (17), which differs from the b-(1!3) backbone with 1!6 branches shared by many other antitumor ...
Cell Pathology Lecture 4
... Figure 17-35 (Molecular Biolology of the Cell, 4th ed) Sculpting the digits in the developing mouse paw by apoptosis (A) The paw in this mouse embryo has been stained with a dye that specifically labels cells that have undergone apoptosis. The apoptotic cells appear as bright green dots between the ...
... Figure 17-35 (Molecular Biolology of the Cell, 4th ed) Sculpting the digits in the developing mouse paw by apoptosis (A) The paw in this mouse embryo has been stained with a dye that specifically labels cells that have undergone apoptosis. The apoptotic cells appear as bright green dots between the ...
Branched-chain amino acids with added L
... BCAA Powder combines the branched-chain amino acids (BCAAs)—leucine, isoleucine, and valine—along with the amino acid, L-glutamine, in a great-tasting, orange flavored powder. BCAAs make up 35% of the essential amino acids in muscle protein, and approximately 40% of the total amino acids required by ...
... BCAA Powder combines the branched-chain amino acids (BCAAs)—leucine, isoleucine, and valine—along with the amino acid, L-glutamine, in a great-tasting, orange flavored powder. BCAAs make up 35% of the essential amino acids in muscle protein, and approximately 40% of the total amino acids required by ...
Secreted human Я-glucuronidase: a novel tool for gene
... resistant tumor cells due to insufficient drug concentrations at the tumor site.1 One possibility to overcome these problems is the use of non-toxic forms of cytotoxic compounds (prodrugs) that are converted to the toxic drug selectively at the tumor site. Strategies using tumorspecific antibodies t ...
... resistant tumor cells due to insufficient drug concentrations at the tumor site.1 One possibility to overcome these problems is the use of non-toxic forms of cytotoxic compounds (prodrugs) that are converted to the toxic drug selectively at the tumor site. Strategies using tumorspecific antibodies t ...
Stem Cell Research: Status and Ethics
... survived to become a cell line (required 16 egg donors to produce one cell line) “Further improvements in SCNT protocols and in vitro culture systems are needed before contemplating the use of this technique for cell therapy.” ...
... survived to become a cell line (required 16 egg donors to produce one cell line) “Further improvements in SCNT protocols and in vitro culture systems are needed before contemplating the use of this technique for cell therapy.” ...
Mapping of linear epitopes on the capsid proteins of swine vesicular
... that originated from one mouse produced antibodies against the recombinant protein. More than 60 mAbs, highly reactive with P1 in ELISA as well as in Western blot assays, were then selected for further characterization. All except four mAbs strongly recognized purified SVDV coated directly to the so ...
... that originated from one mouse produced antibodies against the recombinant protein. More than 60 mAbs, highly reactive with P1 in ELISA as well as in Western blot assays, were then selected for further characterization. All except four mAbs strongly recognized purified SVDV coated directly to the so ...
Corps Member - TFA
... following occurs to create immunity: (HOW) 1) White blood cells produce antibodies in response to the pathogen (the vaccine) 2) Building up these antibodies helps the body “remember” the specific pathogen so that the body’s immune system can more easily destroy such pathogens in the future. KP4: Exa ...
... following occurs to create immunity: (HOW) 1) White blood cells produce antibodies in response to the pathogen (the vaccine) 2) Building up these antibodies helps the body “remember” the specific pathogen so that the body’s immune system can more easily destroy such pathogens in the future. KP4: Exa ...
CD4 and CD8 T Cells Are - The Journal of Immunology
... (LM),3 is a Gram-positive bacterium that invades host cells, escapes from the endosome, and replicates within the host cell cytosol (2). LM proteins are presented by both MHC class I and class II pathways and stimulate strong CD8 and CD4 T cell responses (1, 3). The in vivo dynamics of the CD8 T cel ...
... (LM),3 is a Gram-positive bacterium that invades host cells, escapes from the endosome, and replicates within the host cell cytosol (2). LM proteins are presented by both MHC class I and class II pathways and stimulate strong CD8 and CD4 T cell responses (1, 3). The in vivo dynamics of the CD8 T cel ...
