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Analysis of Differential Gene Expression in a Myotonic Dystrophy
Analysis of Differential Gene Expression in a Myotonic Dystrophy

... log10 (FPKM + 1) of genes at each dosage that are associated the p53 network. FPKM: fragments per kilobase of exon model per million mapped fragments ...
Gene Tagging with Transposons
Gene Tagging with Transposons

... • Transposon is transcribed into RNA, then reverse transcriptase creates “cDNA” that inserts into genome • Two categories exist, based on their origin & structure: ...
Microbial genetics (Ch. 7) Part 3
Microbial genetics (Ch. 7) Part 3

... • Phage also can transduce genes when they insert themselves into the chromosome and later pop out with attached host DNA ...
Leq: what is cloning and how is it done?
Leq: what is cloning and how is it done?

... genomes of various organisms, but the knowledge of full genomes has created the possibility for the field of functional genomics, mainly concerned with patterns of gene expression during various conditions. http://www.news-medical.net/health/What-isGenomics.aspx ...
Human genome study reveals certain genes are less essential than
Human genome study reveals certain genes are less essential than

... the DNA variations of those with severe malaria to those without severe malaria in order to see if genetics could explain why some children fare better than others in a malaria-rife region. They found a gene variation, or “allele”, that is most common in Kenya which reduces the risk of severe malari ...
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powerpoint

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Review of relevant topics prior to “Linkage” lectures
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Name_____________________ Date__________ Class
Name_____________________ Date__________ Class

... is a type of mutation involving the loss of genetic material. It can be small, involving a single missing DNA base pair, or large, involving a piece of a chromosome. any of a group of enzymes that catalyze the cleavage of DNA molecules at specific sites. DNA in which one or more segments or genes ha ...
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Genetic and Genomics: An Introduction
Genetic and Genomics: An Introduction

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Journey Into dna
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Chapter 21 - dewhozitz.net
Chapter 21 - dewhozitz.net

... 2) minisatellites 3) microsatellites = simple sequence repeats = short tandem repeats = variable number tandem repeats C. other non-coding DNA 1. introns & regulatory sequences 2. unique non-coding DNA V. Genes A. most are B. multigene families pseudogenes C. contributing to genome evolution 1. muta ...
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amino acids

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Biotechnology - Hicksville Public Schools / Homepage
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Ch. 19 – Eukaryotic Genomes
Ch. 19 – Eukaryotic Genomes

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lecture 20 notes

... • Number of repeats cannot decrease below 1 by these mechanisms • Mathematically, a random walk with a barrier in only one direction will tend to move away from the barrier • This might be kept in check by selection against the repeat: – DNA replication is expensive – Cells with lots of DNA divide s ...
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... the record of allele replacements in its ancestral lineage. In contrast, Macroevolution of complex phenotypes appears to be mostly independent of Microevolution. ...
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... Used as genetic markers (especially for disease mapping) ...
DNA Replication
DNA Replication

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Barbara McClintock

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7 Self study questions
7 Self study questions

... 1. Explain why ORF scanning is a feasible way of identifying genes in a prokaryotic DNA sequence. 2. What modifications are introduced when ORF scanning is applied to a eukaryotic DNA sequence? 3. Describe how homology searching is used to locate genes in a DNA sequence and to assign possible functi ...
Concepts of Genetics
Concepts of Genetics

... In less than 100 years after Mendel discovered the basic principles of inheritance (1865), ...
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Transposable element



A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.
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