Red line Introduction
... – 19 students used Red Line to visualize next-gen RNA-Seq data to investigate presence/absence variation (PAV) in maize – 12 hours effort, each student group annotated 100 kb and then imported next-gen RNA-Seq data from 5 different tissues in 30 maize inbred lines for a gene that they had previously ...
... – 19 students used Red Line to visualize next-gen RNA-Seq data to investigate presence/absence variation (PAV) in maize – 12 hours effort, each student group annotated 100 kb and then imported next-gen RNA-Seq data from 5 different tissues in 30 maize inbred lines for a gene that they had previously ...
Bioinformatics: A New Frontier for Computer - People
... How to use microarrays to learn more about the influence of drought stress on gene expression? Where the biologists need the computer scientists. A. Confounding factors in the raw data 1. Limitations in accuracy (technique) 2. Biological variation (individuals) B. How to apply corrections for these ...
... How to use microarrays to learn more about the influence of drought stress on gene expression? Where the biologists need the computer scientists. A. Confounding factors in the raw data 1. Limitations in accuracy (technique) 2. Biological variation (individuals) B. How to apply corrections for these ...
1 Evolution of Genome Size 1. The C
... … plus many other neuro-muscular disorders 3. Transposable elements (TEs) Also known as interspersed repetitive elements or “jumping genes” TEs are pieces of DNA that can move within the genome and increase in number. About 50% of the human genome is made up of TEs and remnants of TEs. There are two ...
... … plus many other neuro-muscular disorders 3. Transposable elements (TEs) Also known as interspersed repetitive elements or “jumping genes” TEs are pieces of DNA that can move within the genome and increase in number. About 50% of the human genome is made up of TEs and remnants of TEs. There are two ...
Red Line - iPlant Pods
... – 19 students used Red Line to visualize next-gen RNA-Seq data to investigate presence/absence variation (PAV) in maize – 12 hours effort, each student group annotated 100 kb and then imported next-gen RNA-Seq data from 5 different tissues in 30 maize inbred lines for a gene that they had previously ...
... – 19 students used Red Line to visualize next-gen RNA-Seq data to investigate presence/absence variation (PAV) in maize – 12 hours effort, each student group annotated 100 kb and then imported next-gen RNA-Seq data from 5 different tissues in 30 maize inbred lines for a gene that they had previously ...
Genetic selection and variation
... Genes are a specific sequences of DNA located on the chromosomes. Chromosomes consist of proteins (histones) combined with two complementary chains of DNA. ...
... Genes are a specific sequences of DNA located on the chromosomes. Chromosomes consist of proteins (histones) combined with two complementary chains of DNA. ...
Transposition - Pennsylvania State University
... • Transposase nicks at ends of transposon (note cleavage is at the same sequence, since the ends are inverted repeats). • Transposase also cuts the target to generate 5’ overhangs • The 3’ end of each strand of the transposon is ligated to the 5’ overhang of the target site, forming a crossover stru ...
... • Transposase nicks at ends of transposon (note cleavage is at the same sequence, since the ends are inverted repeats). • Transposase also cuts the target to generate 5’ overhangs • The 3’ end of each strand of the transposon is ligated to the 5’ overhang of the target site, forming a crossover stru ...
Molecular Markers - Personal Web Pages
... May be part of or closely linked to a gene that makes a protein that affects cell survival May be part of controlling elements May be in the larger area of ‘non-coding’ DNA Markers have a known location What is being marked? ...
... May be part of or closely linked to a gene that makes a protein that affects cell survival May be part of controlling elements May be in the larger area of ‘non-coding’ DNA Markers have a known location What is being marked? ...
genet_174(2)_cover 4.qxd
... In Caenorhabditis elegans, mutants in the mrt-2 and hus-1 genes, which are required for both checkpoint-dependent cell cycle arrest and apoptosis, display 8- to 15-fold increases in the frequency of spontaneous mutation in their germlines. However, mutants defective only in the apoptotic branch of t ...
... In Caenorhabditis elegans, mutants in the mrt-2 and hus-1 genes, which are required for both checkpoint-dependent cell cycle arrest and apoptosis, display 8- to 15-fold increases in the frequency of spontaneous mutation in their germlines. However, mutants defective only in the apoptotic branch of t ...
Genetic Markers
... 3x109bp). Using hundreds of markers ensures unknown gene will be close enough to one or two of them to show genetic linkage. • The aim is to find linkage with two markers, one of which is on each side of the disease gene. Then you would know that the disease gene must be in the candidate region of t ...
... 3x109bp). Using hundreds of markers ensures unknown gene will be close enough to one or two of them to show genetic linkage. • The aim is to find linkage with two markers, one of which is on each side of the disease gene. Then you would know that the disease gene must be in the candidate region of t ...
Plant Transposable Elements
... o subterminal repeats (STR) o 5-exon, 807 amino acid transposase o Multiple hexameric repeats within 200 bp of each end Site where transpose binds causes 8bp direct repeat when inserted in new location o repeat sequence used as evidence of element activity Truncated version of Ac Require act ...
... o subterminal repeats (STR) o 5-exon, 807 amino acid transposase o Multiple hexameric repeats within 200 bp of each end Site where transpose binds causes 8bp direct repeat when inserted in new location o repeat sequence used as evidence of element activity Truncated version of Ac Require act ...
Slide 1
... Archibald Garrod, observes that the disease alkaptonuria has a genetic cause and is inherited as a recessive condition. ...
... Archibald Garrod, observes that the disease alkaptonuria has a genetic cause and is inherited as a recessive condition. ...
GENETICS – BIO 300
... several different IS sequences inserted in different places all encode transposase enzyme multiple copies, can recombine ...
... several different IS sequences inserted in different places all encode transposase enzyme multiple copies, can recombine ...
Aliens? - Johns Hopkins Bloomberg School of Public Health
... • Percentage of human genes under miRNA control is unknown but possibly 20-30% • Often are developmental or cell state ...
... • Percentage of human genes under miRNA control is unknown but possibly 20-30% • Often are developmental or cell state ...
ome
... varies depending on the primers but is usually between 50ºC and 60ºC and allows the primers to adhere to the DNA strands; and extension, which occurs at 72ºC, allowing for elongation of the DNA from the primer. 4. Explain the meaning and utility of RNA interference. Answer: RNA interference (RNAi) i ...
... varies depending on the primers but is usually between 50ºC and 60ºC and allows the primers to adhere to the DNA strands; and extension, which occurs at 72ºC, allowing for elongation of the DNA from the primer. 4. Explain the meaning and utility of RNA interference. Answer: RNA interference (RNAi) i ...
Biotechnology Applications
... • Use sequences to study a number of issues – Address questions of evolution by comparing differences and similarities in DNA; greater similarity, more closely related – Study function of different genes & how they are regulated – important with regard to gene therapy ...
... • Use sequences to study a number of issues – Address questions of evolution by comparing differences and similarities in DNA; greater similarity, more closely related – Study function of different genes & how they are regulated – important with regard to gene therapy ...
The Genome of Theobroma Cacao
... The genome, consisting of long strings of chemicals called DNA sequence, includes all the genes of a given organism, but also DNA that is not part of a gene, or noncoding DNA sequence. Each gene contains instructions for assembly of proteins, which consist of strands of amino acids that fold into an ...
... The genome, consisting of long strings of chemicals called DNA sequence, includes all the genes of a given organism, but also DNA that is not part of a gene, or noncoding DNA sequence. Each gene contains instructions for assembly of proteins, which consist of strands of amino acids that fold into an ...
Biological information
... Transcriptional control can be modified by the insertion of transposable elements (e.g. Alu sequences) or mutation. ...
... Transcriptional control can be modified by the insertion of transposable elements (e.g. Alu sequences) or mutation. ...
NOVA – Cracking the Code of Life
... 2. To what degree are all humans identical at the genetic level? 3. About what percentage of the genes in a banana are also in a human? ____ Why is this figure so high? ...
... 2. To what degree are all humans identical at the genetic level? 3. About what percentage of the genes in a banana are also in a human? ____ Why is this figure so high? ...
Cracking the code of life
... Period: _______ 1. What percentage of genes do humans share with bananas? 2. What do you think the message is that has gotten passed from the first form of life? ...
... Period: _______ 1. What percentage of genes do humans share with bananas? 2. What do you think the message is that has gotten passed from the first form of life? ...
Resource - Chromosome Viewer (www
... called deoxyribonucleic acid (DNA). The DNA molecule, in turn, is made up of many smaller components. These nucleotides, or bases, pair up to form the rungs of the DNA ladder. Although there are only four different types of nucleotides in DNA (usually referred to by the first letter of their chemica ...
... called deoxyribonucleic acid (DNA). The DNA molecule, in turn, is made up of many smaller components. These nucleotides, or bases, pair up to form the rungs of the DNA ladder. Although there are only four different types of nucleotides in DNA (usually referred to by the first letter of their chemica ...
Genomes and their evolution
... •Only about 1.5% of the human genome codes for proteins or is transcribed into rRNAs or tRNAs. •The rest, located between functional genes, includes some unique noncoding DNA, such as gene fragments and pseudogenes, former genes that have accumulated mutations over a long time and no longer produce ...
... •Only about 1.5% of the human genome codes for proteins or is transcribed into rRNAs or tRNAs. •The rest, located between functional genes, includes some unique noncoding DNA, such as gene fragments and pseudogenes, former genes that have accumulated mutations over a long time and no longer produce ...
No Slide Title
... The transfer of functional genes from the mitochondria to the nucleus is thought to have has stopped in evolution after the emergence of animals (~1,000 MYA). ...
... The transfer of functional genes from the mitochondria to the nucleus is thought to have has stopped in evolution after the emergence of animals (~1,000 MYA). ...
Macroevolution
... – Humans and chimps diverged from a common ancestor about 5 mya. share about 98.7% of genes ...
... – Humans and chimps diverged from a common ancestor about 5 mya. share about 98.7% of genes ...
GeneticsLecture3
... • Nucleus forces decoupling transscr translat • Two way traffic in/out nucleus – NFB - Transcriptional regulators ...
... • Nucleus forces decoupling transscr translat • Two way traffic in/out nucleus – NFB - Transcriptional regulators ...
What are genomes and how are they studied
... largest total number of domains is 130 largest number of domain types per protein is 9 Mostly identical arrangement of domains no huge difference in domain number in humans, but frequency of domain sharing very high in human proteins (especially structural proteins and proteins involved in sig ...
... largest total number of domains is 130 largest number of domain types per protein is 9 Mostly identical arrangement of domains no huge difference in domain number in humans, but frequency of domain sharing very high in human proteins (especially structural proteins and proteins involved in sig ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.