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Recycling of vitamin B12 and NAD+ within the Pdu
Recycling of vitamin B12 and NAD+ within the Pdu

... Oxidoreductive conversions between the three oxidation states are thus of key importance in the chemistry of vitamin B12. When the oxidation state of the cobalt atom decreases its coordination number tends to decrease accordingly. 1.1.2. Biosynthesis of vitamin B12 According to a widely accepted his ...
The bicoid Protein Determines Position in the Drosophila Embryo in
The bicoid Protein Determines Position in the Drosophila Embryo in

... Another line of evidence that the bcd protein is not only distributed in a graded fashion but that this distribution determines its biological function derives from the analysis of embryos from females with increased or decreased bcd gene dosage. For the anterior pattern we demonstrated that the shi ...
Planta
Planta

... histidines at the N-terminal end of the protein, allowing a one-step puri®cation of the resulting protein. The resulting vectors were named pQE50iso and pQE30iso. As the peptide sequence preceding the pair of arginines was similar to a plastidial transit peptide (Fig. 1), a sequence lacking this 5¢ ...
Appendix 1: PBS listings of Nutritional Products
Appendix 1: PBS listings of Nutritional Products

... Benefits Scheme (PBS). This review focuses on products for cows’ milk protein intolerance following the July 2012 changes to the PBS restrictions for these products. The DUSC requested an analysis of these products at its February 2015 meeting. Date of listing on the Pharmaceutical Benefits Scheme ( ...
- Free Documents
- Free Documents

Eucalyptus Arabidopsis grandis thaliana
Eucalyptus Arabidopsis grandis thaliana

... The ever-growing demand for wood and wood derived cellulose products coupled with the public concern about the clearance of natural flora or agricultural land to make way for the forest tree plantations has sparked a renewed interest in the genetic improvement of forest tree species. Conventional br ...
(LPT1) and humans (LPCAT3)
(LPT1) and humans (LPCAT3)

... the human MBOAT5, a protein with unknown function. Cell lysates from insect cells expressing human MBOAT5 (renamed as LPCAT3) showed a 10 fold increase in LPCAT activity over control. In summary, the identification of a novel LPLAT in yeast has proved to be the founding member of LPLAT family in hum ...
Mitochondrial translation factors of Trypanosoma brucei: elongation
Mitochondrial translation factors of Trypanosoma brucei: elongation

... GTPase activity of EF-Tu is stimulated, causing a conformational change that eventually leads to the release of the aminoacylated tRNA. The GTP exchange factor EF-Ts binds to the GDP-form of EF-Tu and induces its recycling by exchanging GDP for GTP. The conserved bacterial GTPase EF-G has two functi ...
Geometrical and Sequence Characteristics of
Geometrical and Sequence Characteristics of

... 20-dimensional amino acid composition space (Chou and Zhang, 1995). Because these two parameters showed identical trends in all calculations, only the values of Hamming distances have been discussed in detail. Change in proportion of an amino acid in a given helix class is considered to be significa ...
Mitochondrial Dynamics in Mammals
Mitochondrial Dynamics in Mammals

... Mammals have two homologs of Fzo, termed mitofusin 1 (Mfn1) and mitofusin 2 (Mfn2). These proteins are 80% similar to each other and are broadly expressed in a wide range of cell types (Rojo et al., 2002; Santel et al., 2003). Most studies have described a uniform localization of human Mfn1 and Mfn2 ...
embor2011116-sup-0001
embor2011116-sup-0001

... This work exploited the available crystallographic structural details of the amyloid fibril forming hexapeptide NNQQNY, to predict the regions of polypeptide sequences forming amyloid fibrils. The crystal structure of NNQQNY was used to create in silico a collection of near-native templates, or 3D p ...
NMR studies of the methionine methyl groups in calmodulin
NMR studies of the methionine methyl groups in calmodulin

... [3]. NMR and X-ray studies of complexes of CaM with various CaM-binding domain peptides show that all the Met residues, with the possible exception of Met-76, are in contact with the hydrophobic face(s) of the bound peptides [8-12]. Oxidation studies of CaM's Met residues have revealed that all of t ...
REVIEWS - Haseloff Lab
REVIEWS - Haseloff Lab

... activates the ubiquitin moiety by forming a high energy thioester bond between an E1 Cys residue and the carboxy-terminal Gly of ubiquitin (see the figure, part a). This activated ubiquitin is then donated to a Cys on an E2 (or ubiquitin-conjugating enzyme) by trans-esterification. In most cases, th ...
and Rhizobiales-Like PPP-Family Protein Phosphatases from
and Rhizobiales-Like PPP-Family Protein Phosphatases from

... phosphatases from multiple organisms. The primary goal of the research presented here was to elucidate the evolutionary, biochemical, cellular and biological characteristics of two recently identified PPP-family protein phosphatase subclasses from the model photosynthetic Eukaryote Arabidopsis thali ...
Predicting DNA-binding sites of proteins from amino acid sequence
Predicting DNA-binding sites of proteins from amino acid sequence

... contacts that mediate protein-DNA recognition [4-6]. In addition to biophysical methods for structure determination, biochemical and molecular genetic approaches have been widely used to identify DNA-binding sites on proteins and to investigate the interaction modes between proteins and DNA. For exa ...
Ornithodoros savignyi CHAPTER 2  SIGNALING PATHWAYS REGULATING PROTEIN SECRETION FROM
Ornithodoros savignyi CHAPTER 2 SIGNALING PATHWAYS REGULATING PROTEIN SECRETION FROM

... SDS-PAGE analysis of the secreted proteins showed variable results in response to different agonists. The highest number of proteins was detected from ticks in the earliest stages of feeding. In some ticks, proteins were identified at one collection time but not at another time in secretions from th ...
Identification of a Chloroplast-encoded 9-kDa
Identification of a Chloroplast-encoded 9-kDa

... from spinach and showed that this polypeptide contains approximately 8 cysteine residues. Similar results pointing toward the 9-kDa polypeptide as an iron-sulfur protein of PS-I have been obtained in labeling studies with Anacystis nidulans (18). In contrast to these two studies, Bonnerjea et al. (1 ...
Cyclic-‐di-‐AMP: another second messenger enters the fray
Cyclic-‐di-‐AMP: another second messenger enters the fray

... regulator15)  from  B.  subtilis  physically  interacts  with  DacA  and  stimulates  cyclase   activity15.   The   structures   of   two   of   the   four   YbbR   domain-­‐containing   proteins   from   Desulfitobacterium   hafniense   Y51   hav ...
Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase and
Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase and

... in tryptophan metabolism in an attempt to maintain NAD+ levels. These results suggest a connection between ceramide and NAD metabolism. One of the main NAD+-consuming pathways involves sirtuins because they are NAD+-dependent enzymes, and the availability of NAD+ is an important mechanism that regul ...
Progesterone-stimulated intracellular calcium increase in human
Progesterone-stimulated intracellular calcium increase in human

Outer Membrane Vesicle-Mediated Export of
Outer Membrane Vesicle-Mediated Export of

... and PKD2) has not yet been fully investigated, although they have been suggested to be involved in protein-protein or protein-carbohydrate interaction [12]. Our previous studies provided a crystal structure model of the PKD1 domain from V. cholerae PrtV (residues 755– 838) and revealed a Ca++-bindin ...
University of Groningen Lactococcus lactis systems biology Eckhardt
University of Groningen Lactococcus lactis systems biology Eckhardt

Soybean Meal – An Exceptional Protein Source
Soybean Meal – An Exceptional Protein Source

... Soybean meal has long been considered an outstanding source of supplemental protein in diets for livestock and poultry. In fact, soybean meal is sometimes referred to as the "gold standard" because other protein sources are often compared to it. Soybean meal is rich in highly digestible protein, and ...
The Multiple Personalities of the Regulatory Subunit of Protein
The Multiple Personalities of the Regulatory Subunit of Protein

... As the regulatory subunit of a protein kinase that has functions associated with cell cycle progression, CK2β is reminiscent of cyclins that are the regulatory subunits of cyclin-dependent kinases. In a related respect, it is particularly intriguing that CK2β has motifs that have been previously cha ...
Structure, mechanism and function of prenyltransferases
Structure, mechanism and function of prenyltransferases

... Over the past decade, many trans-IPPSs have been purified and their genes cloned [45,46]. The deduced amino-acid sequences of these enzymes show amino-acid sequence homology and two common DDxxD motifs [47], suggesting that they evolved from the same origin (Fig. 2) [48,49]. These Asp-rich motifs wer ...
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Magnesium transporter

This page links directly from the magnesium in biological systems page.Magnesium transporters are proteins that transport magnesium across the cell membrane. All forms of life require magnesium, yet the molecular mechanisms of Mg2+ uptake from the environment and the distribution of this vital element within the organism are only slowly being elucidated.In bacteria, Mg2+ is probably mainly supplied by the CorA protein and, where the CorA protein is absent, by the MgtE protein. In yeast the initial uptake is via the Alr1p and Alr2p proteins, but at this stage the only internal Mg2+ distributing protein identified is Mrs2p. Within the protozoa only one Mg2+ transporter (XntAp) has been identified. In metazoa, Mrs2p and MgtE homologues have been identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been identified along with another novel protein, AtMHX.
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