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Chapter 9 Presentation
Chapter 9 Presentation

... • This is known as the “link reaction.” • It is here that pyruvate is converted into acetyl CoA and enters the citric acid cycle where the breakdown of glucose is completed. • In this process, CO2 is given off and a small amount of ATP is made, and NADH and FADH2 are generated. ...
Endocrinology of the Pancreas and Diabetes Mellitus
Endocrinology of the Pancreas and Diabetes Mellitus

... acetyl CoA carboxylase (transcription) fatty acid synthase ...
Phenylketonuria (PKU)
Phenylketonuria (PKU)

... concentration of 26.4 mg/dL at 6 days old. Excessive bioactive substances intake (too much Phenylalanine) RT nutrition-related knowledge deficit AEB increased levels of Phe and a Guthrie test positive for PKU. ...
the use of guaifenesin in fibromyalgia
the use of guaifenesin in fibromyalgia

... Fifty-five years ago we began treating fibromyalgia (then nameless) with uricosuric agents. Twenty-two years ago we found a potent, therapeutic value from the barely uricosuric guaifenesin that we have now used for over ten thousand patients (3). Cyclic clearing reproduces prior symptoms reminiscent ...
Malonyl CoenzymeA Decarboxylase Regulates Lipid and
Malonyl CoenzymeA Decarboxylase Regulates Lipid and

... or oxidation impacting on glucose disposal. In humans, intramyocellular lipid levels of skeletal muscle are inversely correlated with whole-body insulin sensitivity (1). Increasing evidence suggests that extensive triacylglycerol accumulation in skeletal muscle (i.e., ectopic fat deposition) impairs ...
Gene–Nutrition Interaction in Human Performance and Exercise
Gene–Nutrition Interaction in Human Performance and Exercise

... exercise training was the angiotensin-converting enzyme (ACE) gene. ACE is part of the renin-angiotensin pathway, and an insertion/deletion (I/D) polymorphism in intron 16 of the ACE gene has been well studied for its association to hypertension and left ventricular hypertrophy in multiple study pop ...
Related Metabolic Processes
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... • The metabolic pathways of respiration also play a role in anabolic pathways of the cell. • Not all the organic molecules of food are completely oxidized to make ATP. • Intermediaries in glycolysis and the Krebs cycle can be diverted to anabolic pathways. • For example, a human cell can synthesize ...
CHAPTER 9 CELLULAR RESPIRATION: HARVESTING CHEMICAL
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... • The metabolic pathways of respiration also play a role in anabolic pathways of the cell. • Not all the organic molecules of food are completely oxidized to make ATP. • Intermediaries in glycolysis and the Krebs cycle can be diverted to anabolic pathways. • For example, a human cell can synthesize ...
Citric Acid Cycle
Citric Acid Cycle

... • Process in which cells consume O2 and produce CO2 • Provides more energy (ATP) from glucose than Glycolysis • Also captures energy stored in lipids and amino acids • Evolutionary origin: developed about 2.5 billion years ago • Used by animals, plants, and many microorganisms • Occurs in three majo ...
Tutorial: Metabolic Signaling in the b-Cell
Tutorial: Metabolic Signaling in the b-Cell

... All cells in the body convert glucose and other fuels to adenosine triphosphate (ATP), the primary energy molecule. The ATP powers many of the energy-requiring chemical reactions that occur in the cell. However, in b-cells the ATP molecule and several intermediates of metabolism act also as signalin ...
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07_Metabolism of aminoacids

... - oxidative (the most important for higher animals), ...
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Citric acid cycle ELECTRON TRANSPORT CHAIN AND

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biochemichistry of the eye
biochemichistry of the eye

CITRIN DEFICIENCY
CITRIN DEFICIENCY

... distributed over the entire surface) is present in a group of children with more severe biochemical alterations. Although NICCD form is usually not severe and the symptoms are generally resolved by the first year of age with proper treatment, may even be fatal in some children due to infection and l ...
Acid – base balance
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... An arterial pCO2>90 mmHg is not compatible with life in patients breathing room air: pAO2 = [0.21x(760-47)]-90/0.8 = 37 mmHg ...
Mitochondrial Cytopathies: A Primer
Mitochondrial Cytopathies: A Primer

... dehydrogenase deficiency. Comments: LCAD is the first step in the sequential beta-oxidation of long chain fats (dietary or stored). With LCAD deficiency, one cannot rely on fats for energy. R.L. relied on his wife to cook his meals, and when she died, R.L was on his own for the first time in his lif ...
De novo lipogenesis in the liver in health and disease: more than
De novo lipogenesis in the liver in health and disease: more than

... Hepatic de novo lipogenesis (DNL) is the biochemical process of synthesising fatty acids from acetyl-CoA subunits that are produced from a number of different pathways within the cell, most commonly carbohydrate catabolism. In addition to glucose which most commonly supplies carbon units for DNL, fr ...
You Light Up My Life
You Light Up My Life

... Lactate Fermentation • Carried out by certain bacteria • No mitochondria, so where does this take place? • Electron transfer chain is in bacterial plasma membrane • Final electron acceptor is compound from environment (such as nitrate), not oxygen • ATP yield is low ...
how cells release chemical energy
how cells release chemical energy

... forming two NADH. b. Intermediates form; each releases a hydrogen atom and an -OH group. These combine as water. Two molecules of PEP form by the reactions. c. First, one ATP molecule transfers a phosphate group to glucose, then another; atoms are rearranged, because the cell has now invested two AT ...
oxidation
oxidation

... – involves electrons carried by NADH and FADH2, – shuttles these electrons to the electron transport chain embedded in the inner mitochondrial membrane, – involves chemiosmosis, and – generates ATP through oxidative phosphorylation ...
Cell Respiration notes
Cell Respiration notes

... Occurs in the matrix of the mitochondria Compared with glycolysis, Kreb’s Cycle pays big energy dividends to the cell This makes 1 ATP, 3 NADH and 1 FADH2, per acetyl coA (2-C) (double that for each glucose molecule) Releases CO2 as waste is aerobic (requires oxygen) ...
AnaerobicAerobic CellResp
AnaerobicAerobic CellResp

INTRODUCTION TO CELLULAR RESPIRATION
INTRODUCTION TO CELLULAR RESPIRATION

File - twynham a level pe
File - twynham a level pe

... Lactate threshold is a percentage of VO2max The higher the VO2 max, the more the delay in lactic acid build-up/as VO2max increases, so does lactate threshold Trained athletes can exercise for longer periods at the same/higher intensity compared to an untrained athlete/lactate threshold a much higher ...
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Ketosis



Ketosis /kɨˈtoʊsɨs/ is a metabolic state where most of the body's energy supply comes from ketone bodies in the blood, in contrast to a state of glycolysis where blood glucose provides most of the energy. It is characterised by serum concentrations of ketone bodies over 0.5 millimolar, with low and stable levels of insulin and blood glucose. It is almost always generalized with hyperketonemia, that is, an elevated level of ketone bodies in the blood throughout the body. Ketone bodies are formed by ketogenesis when liver glycogen stores are depleted (or from metabolising medium-chain triglycerides). The main ketone bodies used for energy are acetoacetate and β-hydroxybutyrate, and the levels of ketone bodies are regulated mainly by insulin and glucagon. Most cells in the body can use both glucose and ketone bodies for fuel, and during ketosis, free fatty acids and glucose synthesis (gluconeogenesis) fuel the remainder.Longer-term ketosis may result from fasting or staying on a low-carbohydrate diet, and deliberately induced ketosis serves as a medical intervention for intractable epilepsy. In glycolysis, higher levels of insulin promote storage of body fat and block release of fat from adipose tissues, while in ketosis, fat reserves are readily released and consumed. For this reason, ketosis is sometimes referred to as the body's ""fat burning"" mode.
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