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Review sheet – Chapter 9 Know that genetics is the science of heredity Understand that genes are discrete units of genetic (hereditary) information consisting of a specific nucleotide sequence of DNA Know who Gregor Mendel was and what he worked with (garden pea plants); understand the principles that he established, and be able to describe how he tested the mechanisms of heredity (be able to provide an example of a character he studied, understand what a truebreeding line and how he used these to test how traits were transferred from one generation to the next Understand what a true-breeding line is (above), and what an F1 (offspring of 2 true-breeding lines for different traits) and F2 generation (offspring of 2 F1 generations) is Know the definition of an allele Understand what homozygous and heterozygous mean Understand what is meant by a dominant and a recessive allele Understand what the difference is between a genotype and phenotype Be able to define a homozygous recessive, homozygous dominant or heterozygous genotype if given the alleles (ex. Bb or BB or bb) Understand that phenotypes can reveal the genotype if recessive Be able to name possible genotypes if given a phenotype Understand what a testcross is Understand that the probability of an event that is certain to occur is 1, while an event that is certain not to occur is 0 Understand that most genetic disorders are recessive…why? Understand that a carrier of a recessive allele is heterozygous for the allele (ex. Cc) but does not exhibit the trait phenotypically Be able to determine what offspring would be expected to be produced by a couple if given their genotypes (ex. A female tiger who is heterozygous for coat color (Cc) mates with a male that is homozygous recessive (cc) for coat color; the female produces gametes that are either C or c, while the male produces gametes that are c and c; the resulting offspring would be C x c = Cc; c x c = cc; C x c = Cc, and c x c = cc) See examples from your slides for this… Be able to explain why inbreeding increases the risk of genetic disorders in offspring produced by such pairings Understand that Huntington’s disease is caused by a dominant allele Understand what incomplete dominance is (homozygous dominant are one color, homozygous recessive are another color, and heterozygous are another color) Understand that human blood type is an example of codominance. Be able to describe potential genotypes of an individual is given his/her phenotype and the blood type of potential offspring if given the blood type of 2 ‘parents’. For each blood type, know which types individuals can receive and donate to. Understand what a linked gene is Understand what a sex-linked gene is, and know that hemophilia is an example of one