Download Holly Gets Sick

Name_________________________________Period____Date__________________
Honors Biology
Body Stories Video Lab: “Holly Gets Sick”
In this video, a young rock singer becomes ill before a major performance with her band. Her body goes into
battle by using defense mechanisms to combat the virus. Look at the virus diagram below. How does is it
similar to the virus you drew in your lab notes?
Study the diagram below to identify the type of infection. Circle the genetic material; box the protein coat.
These are the two main parts of all viruses.
The above virus will attack Holly. In order for it to be successful, it must…
1. Enter
2. Spread
3. Multiply
4. Damage
What will be the outcome for Holly?
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As you watch the video, answer the following questions as best as you can.
1. Holly is standing in an elevator. What did one of the other elevator riders do while she was standing
there? ___________________________________________
2. What structure(s) or secretions try to prevent the pathogen from entering Holly’s body?
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3. Influenza B virus is the pathogen that is invading Holly’s body. What specific cell must it invade to take
hold of her body? ____________________________________ What part of the virus will allow for
the virus to invade these cells? ____________________________________ What part of the cell will
allow the invasion to happen?
4. How do Holly’s cells respond once the virus commandeers the cell? (Which viral life cycle is beginning?
________________________
5. What type of defense cell kills both infected and non-infected cells in Holly’s body?
____________________________
6. What type of defense cell moves through tissues “cleaning up” cellular debris from Holly’s infection?
____________________________ How do they do this?
7. What chemical is released by the macrophages to inhibit viral reproduction?
__________________________
8. Dendritic cells, located in lymph nodes, are necessary to start up Holly’s specific defense mechanisms.
What type of defense cell does a dendritic cell seek out_____________________
9. What causes swollen lymph nodes?
10. Mast cells, another type of defense cell, release a chemical known as “histamine” which causes
____________________________.
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11. The part of the brain, known as the hypothalamus, is responsible for regulating body temperature.
What symptom is an elevated body temperature? _________________________________
12. Interleukins are release into the blood stream and…
a) make blood vessels in her brain to swell & cause what body symptom? __________________
b) make nerve cells hypersensitive and cause what body symptom? _______________________
Holly’s body’s immune system is hard at work trying to destroy specific viruses before they can infect new
cells. Specific immune cells will be doing specific jobs. The functions of specific ones are listed below. List
the names as you hear them.
Post Video Assignment: Read 24.1-6 and then answer the following questions.
1. Which immune cell is it?
a) are matured in the lymph nodes ___________________________, _______________________________
b) manufacture antibodies ____________________________
c) activates a T-cell to destroy infected cells ______________________________
d) makes body immune to future infection _____________________________
e) leaves lymph nodes to destroy infected cells _____________________________________
f) remains in the lymph nodes _____________________________________
2. Research: What is a vaccine and what is its purpose?
3. How does an antibody deactivate an antigen? (Use term epitope).