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Respiratory System Disorders Diseases and Infections interfere in two main ways: 1) Restrict the flow of air into and out of the lungs 2) Impairs the gas exchange due to a reduced surface area for diffusion Pneumonia • Alveoli become inflamed & fill with thick fluid • Inflammation of the lining of the bronchi • Decreased airway & impaired gas exchange 2 types of Pneumonia • See fig 11.13 page 456 • Bronchial pneumonia affects patches in both lungs • Lobular involves a single lobe and most often caused by bacteria Causes of Pneumonia • Bacterial infection / viral infection • Can spread to other organs • Treated with anti-virals or antibiotics Bronchitis - Tissue of the bronchi become red, inflamed, and filled with mucus - Restricts air flow Causes of bronchitis - Acute bronchitis (short-term) = bacteria - Chronic bronchitis (long-term) = regular exposure to dust, chemicals, cigarette smoke * Cilia lining is gradually destroyed Asthma • Inflammation of the bronchi and bronchioles • Air flow is reduced • Muscles around the airway contract during an asthma attack Causes of Asthma • Inhaled irritants such as pollen, dust and smoke • Asthma medications act by relaxing the bronchiole muscles by reducing inflammation Emphysema • Tissue that supports the structure of the lung is destroyed • The elasticity of the alveoli is lost • Reduces the respiratory surface for gas exchange • Exhalation is difficult – trapping air in the lungs Most common cause is SMOKING Cystic Fibrosis Effects of CF • Cells lining the airways release thick, sticky mucus • Clogs the lungs • Mucus traps disease causing agents