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Work of Gregor Mendel Section 11-1 Pages 263-266 Standard IV Objective 2a: Explain Mendel’s laws of segregation and independent assortment and their role in genetic inheritance. Genetics Vocabulary Trait: specific characteristic Gene: sequence of DNA that codes for a protein thus determining a trait Alleles: different forms of a gene Gregor Mendel Gregor Mendel—father of genetics Conducted his work in the garden of a monastery—changed biology forever Worked with true breeding pea plants True breeding—produce identical offspring if allowed to self-pollinate He looked at 7 different traits Alleles Where do living organisms get alleles from? Organisms receive one allele for each trait from each parent. Principle of Dominance: some alleles are dominant and other are recessive If a dominant allele is present, the organism will take on the characteristic of the dominant allele. PTC paper Alleles Representing different alleles T (capital letter) = dominant trait t (lower case) = recessive trait For each trait there are two alleles (one from each parent) Example: Plant height TT and Tt tt Probability Principle of Probability: used to predict outcomes of genetic crosses Homozygous – 2 identical alleles Homozygous dominant (TT) Homozygous recessive (tt) Heterozygous – 2 different alleles (Tt) Mendel’s Crosses Original pair of plants—P (parental) generation The offspring of the P generation are called the F1 generation The offspring of the F1 generation are called the F2 generation Hybrid—the offspring of crosses between parents with different traits Results of Crosses Mendel took the true breeding plants with contrasting characteristics and crossed them. Tall plant x Short plant Took it another step: he allowed all hybrid plants to produce an F2 generation by self-pollination Genetic Vocabulary Heterozygous—organisms that have two different alleles for the same trait Homozygous—organisms that have two identical alleles for a particular trait Genotype—genetic makeup (TT, Tt, tt) Phenotype—physical characteristics (the plant is tall or the plant is short) Punnett Squares Dad is heterozygous for a particular trait Mom is homozygous recessive for the same trait What is the projected outcome of this cross? Ratios Genotypic Ratio How many of each genotype do I have? Do not reduce ratio!!! H.D.:H.:H.R. Ex. 1:2:1 Must add up to total number of boxes Phenotypic Ratio How may of each phenotype do I have? Is the plant tall or short? Ex. 3:1 Picture Credits http://history.nih.gov/exhibits/nirenberg/images/photos/01_mendel_p u.jpg http://www.jbhs.k12.nf.ca/biology/photos/jillear2.jpg http://sdmc.lit.org.sg/gedm/imageANDdata/gene.gif http://www.naturalselectionreptiles.com/Genetics/allele.jpg http://www.bbc.co.uk/schools/gcsebitesize/img/bipeas.gif http://psychservices.ucsd.edu/resources_parents_web/resources_p arents_images/resources_parents_help.jpg http://images.google.com/imgres?imgurl=http://i21.photobucket.com/ albums/b268/plopperscioly/punnettsquare.jpg&imgrefurl=http:// http://stavos.homeip.net/detroitarchive/uploadcenter/images/tigon.jp g http://cricket.biol.sc.edu/herb/CC/Centrosema_virginianum2.jpg http://users.adelphia.net/~lubehawk/BioHELP!/psquare0.jpg