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Regulation of Gene Expression Pages 351-377 Key Concepts Bacteria often respond to environmental change by regulating transcription. Eukaryotic gene expression can be regulated at any stage. Noncoding RNAs play multiple roles in controlling gene expression. A program of differential gene expression leads to the different cell types in a multicellular organism. Cancer results from genetic changes that affect cell cycle control. 18.1 Bacteria often respond to environmental change by regulating transcription. Operons- Tryp and Repressible Operon Lac Operon- An inducible enzymes Positive Gene Regulation 18.2 Eukaryotic gene expression can be regulated at any stage. Differential Gene Expression Regulation of Chromatin Structure Histone modification DNA Methylation Regulation of Transcription Initiation Stages of gene expression that can be regulated Eukaryotic Gene Organization Enhancers and Activators Mechanisms of Post Transcriptional Control RNA processing mRNA degradation Initiation of Translation Protein processing and Degradation 18.4 A program of differential gene expression leads to the different cell types in a multicellular organism Cell Differentiation Morphogenesis Cytoplasmic determinants and Inductive signals Determination and Differentiation Pattern formation Determination and Differentiation of Muscle Cells Life cycle of drosophilia From egg to larvae 18.5 Cancer results from genetic changes that affect cell cycle control Oncogenes and proto oncogenes Tumor suppressor genes Proto-oncogenes can become oncogenes Cell cycle stimulating pathway Cell cycle inhibiting pathway Effects of Mutations Multistep path to cancer