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KERATIN
a family of fibrous structural
proteins which form the
exterior structure of reptiles,
birds, amphibians, and
mammals
What is the need for Keratin?
• The protein creates a hard surface
• Used in hooves, hair, nails
• Serve as an insulating layer to protect
the delicate new keratin below dead
cells because the protein is mostly
formed by dead cells which body sheds
as new cells pushes up underneath it
Nucleotide and
amino acid
sequences of the 40k Da (H40) human
keratin
The most common amino acids
found in keratins …
Alananin
Cysteine
Glycine
Intermolecular
STRUCTURE
hydrogen bonding
APPEARANCE
KERATIN IN WOOL
Increased strength
of the protein
Disulphide
bonds make
Keratin
Helical
affects
Ionic
and structure
hydrophobic
chemical
fibers
insoluble
in
water
and
flexibility,
resilience,
cross
links
stabilize
the
protein
more resistant to chemical and
elasticity
and
wrinkling
of
in
wet and
dry
conditions.
physical
attacks.
(covalent
bond of wool
two thiol groups)
Why I chose Keratin?
Another Significance?
Another important use for keratin is
that its used in hair. There is a such
thing as Keratin Treatment. It is used to
make frizzy and curly hair, straight and
smooth. Keratin makes the hair tough
and insoluble due to the high amount
of sulphur and the amino acid,
cysteine.
BIBLIOGRAPHY
Pine, Chris. Why Wool? 23 Apr. 2008: n. pag. Web. 15 Oct. 2009.
<http://itech.dickinson.edu/chemistry/?cat=69>.
Pine, Chris. Keratin. 23 Apr. 2008: n. pag. Web. 15 Oct. 2009.
<http://itech.dickinson.edu/chemistry/?cat=69>.
Eckert, R. Human 40-kDa Keratin . "Sequence of the human 40-kDa keratin reveals
an unusual structure with very high sequence identity to the corresponding
bovine keratin." PubMed Central: 1115. N.p., n.d. Web. 15 Oct. 2009.
<http://www.ncbi.nlm.nih.gov/pmc/articles/PMC279716/?page=2>.