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Chapter 12 – Molecular Biology of the Gene Replication, Transcription and Translation The Shape of Things Scientific Discoveries DNA and RNA $100 $100 $100 $100 $200 $200 $200 $200 $300 $300 $300 $300 $400 $400 $400 $400 $500 $500 $500 $500 FINAL ROUND Scientific Discoveries $100 Question Griffith is credited with discovering this process when heat killed pneumonia bacteria changed non disease causing bacteria to pneumonia causing bacteria. This process is called ANSWER BACK TO GAME Scientific Discoveries $100 a. Translation b. Transformation c. Transcription d. Reduction Scientific Discoveries $200 Question Hershey and Chase are credited with using a certain viruses to infect bacteria to determine that DNA is indeed the heredity molecule. This type of specific virus used was a….. ANSWER BACK TO GAME Scientific Discoveries $200 a. Rhinovirus b. Retrovirus c. Bacteriophage d. papovavirus Scientific Discoveries $300 Question Edwin Chargaff is credited with discovering that samples of DNA contained equal amounts of adenine and thymine and equal amounts of guanine and cytosine. This discovery is called the rules of ANSWER BACK TO GAME Scientific Discoveries $300 a. Alignment b. Base pairing c. Parallel forms d. Antiparallel form Scientific Discoveries $400 Question These two scientists were awarded the Nobel Prize in science for their discovery of the structure of DNA. Who are they? ANSWER BACK TO GAME Scientific Discoveries $400 a. Watson and Crick b. Avery and Avery c. Franklin and Chase d. Wallace and Darwin Scientific Discoveries $500 Question Hershey and Chase used radioactive tracers in their experiments with bacteriophages. Which labeled virus compenent ended up in the bacteria, the radioactive sulfur on the protein or the radioactive phosphorus on the DNA? ANSWER BACK TO GAME DNA and RNA $100 Question Both RNA and DNA are composed of smaller subunits containing a 5 carbon sugar, phosphate group and a nitrogen base. These small monomers are called BACK TO GAME DNA and RNA $100 a. Hydrogen bonds b. Amino acids c. Nucleotides d. proteins RNA and DNA $200 Question DNA and RNA differ in the 5 carbon sugar. How? BACK TO GAME DNA and RNA $200 a. The 5 carbon sugar in DNA is ribose and the RNA is deoxyribose b. The 5 carbon sugar in DNA is deoxyribose and RNA is ribose c. The 5 carbon sugar in DNA is dextrose and in RNA sucrose d. The 5 carbon sugar in DNA is sucrose and in RNA dextrose RNA and DNA $300 Question RNA differ in their nitrogen bases. Both have these 3 bases in common, but differ in a fourth. What bases do they both share and what base is different? ANSWER BACK TO GAME DNA and RNA $300 a. The base that is different is thymine in RNA and uracil in DNA. A, C, G are all the same b. The base that is different is DNA has no adenine but RNA does, and TCG are all shared c. The base that is different is DNA has thymine but RNA has uracil and CGA are all shared RNA and DNA $400 Question The shape of the DNA and RNA differ as well. How would you describe this difference? BACK TO GAME DNA and RNA $400 a. The DNA is a single strand and RNA is double b. They are not different c. The DNA is three strands and the RNA is 2 strands d. The DNA is double strand and the RNA is a single strand RNA and DNA $500 Question Replication of DNA to DNA and transcription of DNA to mRNA both occur in this part of the cell. ANSWER BACK TO GAME DNA and Rna $500 a. Nucleus b. Cytoplasm c. Mitochondria d. ribosome Replication, Transcription, and Translation $100 Question Replicate the following DNA strand: AGTCTAGGC ANSWER BACK TO GAME Replication, Transcription, Translation $200 Question Transcribe the following DNA strand to mRNA GCTAAGTCG ANSWER BACK TO GAME Replication, Transcription, Translation $300 Question While replication and transcription occur in the nucleus of the cell, translation occurs in the cytoplasm at this organelle? ANSWER BACK TO GAME Replication, Transcription, Translation $400 a. Golgi apparatus b. Endoplasmic reticulum c. Mitochondria d. ribosome Replication, Transcription, Translation $400 Question The process of translation involves the translation of mRNA to the sequence of ______ which are then bonded to form a ________________. ANSWER BACK TO GAME Replication, Transcription, Translation $400 a. Amino acids….protein b. Nucleotides…codon c. Codon…anticodon d. Protein…nucleotide Replication, Transcription, Translation $500 Question Each string of 3 nucleotide bases form the “words” which code for amino acids. These are called ______ while the tRNA carries the ________________ for protein synthesis to occur. ANSWER BACK TO GAME Replication, Transcription, Translation $500 a. adenine, thymine b. Amino acid..antiamino acid c. Codon, anticodon d. Leucine, arginine The Shape of Things $100 Question The diagram in the next slide is a: a. Protein b. Nucleotide c. Amino acid d. codon ANSWER BACK TO GAME ) Phosphate group Uracil (U) Sugar (ribose) $200 The Shape of Things The difference between the purines and pyramidines is in the shape, what is it? $200 The Shape of Things $300 The Shape of Things The next slide is considered a chart of what chemical structures? $300 The Shape of Things $400 The Shape of Things The shape of DNA is often called: The Shape of Things $500 Question This describes any change to a sequence of nucleotides that may or may not affect the protein structure. ANSWER BACK TO GAME $500 The Shape of THings a. Alteration b. Deformation c. Misalignment d. mutation FINAL ROUND Question There are several mutations discussed in class. Which is one that causes the most serious effect on the protein, and why does it cause it? a. Base substitution b. Base insertion c. Base duplication ANSWER BACK TO GAME