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AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (1) ATP • ATP is the only form of usable energy in the body. • Energy is released from ATP when it is broken down into ADP + Pi. • Stores of ATP last for only 3 seconds. • When ATP stores are depleted, they need to be replenished immediately. AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (2) Energy systems There are three energy systems that can regenerate ATP: • the ATP–PC system (anaerobic) • the lactic acid system (anaerobic) • the aerobic system AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (3) Energy systems The use of each of these systems depends on the intensity and duration of the activity: • If the activity is short duration (less than 10 seconds) and high intensity, we use the ATP–PC system. • If the activity is longer than 10 seconds and up to 3 minutes at high intensity, we use the lactic acid system • If the activity is long duration and submaximal pace, we use the aerobic system. AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (4) The energy continuum Sometimes we need to use all three systems to regenerate ATP because the demands of an activity are varied. For example, in rugby: • a short sprint to tackle a player uses the ATP–PC system • a long sprint the length of the pitch to score a try uses the lactic acid system • positional play will use the aerobic system AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (5) What you need to know about energy systems • Type of reaction • The chemical or food fuel used • Where the reaction occurs • The energy yield (how many ATP molecules) • Specific stages in a system • The by-products • When the system is predominant AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (6) The ATP–PC system Type of reaction — anaerobic coupled Fuel used — phosphocreatine The reaction occurs — in the sarcoplasm Energy yield — 1 ATP Specific stages in the system — PC is stored in the muscle and broken down to release energy; this energy is used to regenerate ATP • By-products — none • The system is predominant in high-intensity activity lasting less than 10 s, e.g. 100 m sprint or a slam dunk • • • • • AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (7) The ATP–PC system Advantages • Phosphocreatine stores can be regenerated quickly (50% replenishment in 30 s; 100% in 3 mins) • No fatiguing by-products • Creatine supplementation extends the time that the ATP–PC system can be utilised AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (8) The ATP–PC system Disadvantages • There is a limited supply of phosphocreatine in the muscle cells, i.e. it can only last for 10 s • Only 1 molecule of ATP can be regenerated for every molecule of PC • PC regeneration can only take place in the presence of oxygen (i.e. when the intensity of the exercise is reduced) AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (9) The lactic acid system Type of reaction — anaerobic coupled Fuel used — glycogen The reaction occurs — in the sarcoplasm Energy yield — 2 ATP • Specific stages in the system — glycogen is broken down into glucose and in the absence of oxygen forms pyruvic acid • By-product — lactic acid • The system is predominant — in high-intensity activity lasting between 10 s and 3 min, e.g. a succession of tackles in rugby, or a full court press followed by a fast break in basketball • • • • AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (10) The lactic acid system Advantages • ATP can be regenerated quite quickly because few chemical reactions are involved. • In the presence of oxygen, lactic acid can be converted back into liver glycogen, or used as a fuel by oxidation into carbon dioxide and water. • It can be used for a sprint finish (i.e. to produce an extra burst of energy). AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (11) The lactic acid system Disadvantages • Lactic acid is the by-product! The accumulation of acid in the body denatures enzymes and prevents them increasing the rate at which chemical reactions take place. • Only a small amount of energy (5%) can be released from glycogen under anaerobic conditions (as opposed to 95% under aerobic conditions). AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (12) The aerobic system • Type of reaction — anaerobic coupled • Fuel used — glycogen/fats • The reaction occurs — stage 1 (glycolysis) in the sarcoplasm; stage 2 (Kreb’s cycle) in the matrix of the mitochondria; stage 3 (electron transport) in the cristae of the mitochondria • Energy yield — stage 1: 2 ATP; stage 2: 2 ATP; stage 3: 34 ATP AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (13) The aerobic system • Specific stages in the system — stage 1 glycolysis; stage 2 Kreb’s cycle; stage 3 electron transport • By-products — carbon dioxide (stage 2); water (stage 3) • The system is predominant in sub-maximal exercise such as keeping up with play AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (14) The aerobic system Advantages • More ATP can be produced — 38 ATP from the complete breakdown of one glucose molecule. • There are no fatiguing by-products (only carbon dioxide and water). • Stores of of glycogen and triglyceride are plentiful, so exercise can last for a long time. AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (15) The aerobic system Disadvantages • This is a complicated system so it cannot be used immediately. It takes time for enough oxygen to become available to meet the demands of the activity and ensure glycogen and fatty acids are completely broken down. • Fatty acid transportation to muscles is low and fatty acids require 15% more oxygen to break them down than glycogen. AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (16) Food fuels Food is the basic form of energy for ATP regeneration. The main energy foods are: • carbohydrates — stored as glycogen and converted into glucose during exercise • glycogen — a complex sugar supplied from muscle or liver stores • glucose — a simple sugar supplied from the blood • fats — stored as triglycerides in adipose tissue under the skin and converted by the enzyme lipase to free fatty acids when required AS/A2 PE: Anatomy & Applied Exercise Physiology ERP 10 (17) When are these fuels used during exercise? • The intensity and duration of exercise play a huge a role in determining whether fats or carbohydrates are used. • The breakdown of fats to free fatty acids requires more oxygen than that required to breakdown glycogen. It is also a much slower process. • Therefore, during high-intensity exercise when oxygen is in limited supply, glycogen will be the preferred source of energy.