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Transcript
Piperazines ⢠Structurally related to the ethylenediamines and the ethanolamines and thus produce significant anti-cholinergic effects ⢠Used most often to treat motion sickness, vertigo, nausea and vomiting Cyclizine â¢Used to treat the symptoms associated with motion sickness, vertigo and post-op following administration of general anaesthesia and opiods http://en.wikipedia.org/wiki/Image:Cyclizine.svg â¢Mechanism of inhibiting motion sickness is not well understood, but it may act on the labyrinthine apparatus and the chemoreceptor trigger zone (area of the brain which receives input and induces vomiting)
