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Hormonal Control of Digestion QuickTime™ and a decompressor are needed to see this picture. Gastrin = hormone produced by gastric glands in lower stomach wall. LE 41-19 Liver Bile Gallbladder • Triggered by entry of food into the stomach -> and the Gastrin + stretching of the stomach Stomach Acid chyme Intestinal juice Pancreatic juice Duodenum of small intestine Pancreas Gastrin LE 41-19 Liver Bile Gallbladder • Secreted from the stomach mucosa (lining) • Enters the Gastrin + bloodstream • Increases HCl & stomach churning Stomach Acid chyme Intestinal juice Pancreatic juice Duodenum of small intestine Pancreas Secretin = hormone produced in cells of the small intestine LE 41-19 Liver Bile Gallbladder Stomach Acid chyme Intestinal juice Pancreatic juice Duodenum of small intestine Secretin + Pancreas • Triggered by HCl acid in the chyme • Hormone enters bloodstream and targets pancreas & liver. • Output of pancreatic juices, and bile from liver, is the result. Secretin = hormone produced in cells of the small intestine LE 41-19 Liver Bile Gallbladder Stomach Acid chyme Intestinal juice Pancreatic juice Duodenum of small intestine Secretin + Pancreas • Specifically, release of buffer, into Small Intestine • This neutralizes the acidic chyme coming into the small intestine Secretin = hormone produced in cells of the small intestine QuickTime™ and a decompressor are needed to see this picture. • ALSO, stimulates the liver to produce bile • BILE = emulsifies FAT CCK = hormone produced in cells of the small intestine LE 41-19 Liver Bile Gallbladder CCK + Stomach Acid chyme Intestinal juice Pancreatic juice Duodenum of small intestine Pancreas • Triggered by partially digested protein & fat that enters the sm. intestine CCK = hormone produced in cells of the small intestine QuickTime™ and a decompressor are needed to see this picture. • Stimulates Gallbladder contraction to release bile • Stimulates Pancreas to release enzymes Enterogastrone LE 41-19 Liver Gallbladder Bile Enterogastrone - Stomach Acid chyme Intestinal juice Pancreatic juice Duodenum of small intestine Pancreas • Produced in small intestine • Triggered by acid rich chyme (rich in fat) entering the small intestine. • Target cells in the stomach Enterogastrone LE 41-19 Liver Gallbladder Bile Enterogastrone - Stomach Acid chyme Intestinal juice Pancreatic juice Duodenum of small intestine Pancreas • Inhibits peristalsis and acid secretion of the stomach • Slows digestion in the stomach.