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Keystone Module B: Continuity and Unity of Life Top Twelve Review 1) Describe the events that occur during the cell cycle: a) interphase: b) nuclear division (i.e., mitosis or meiosis): ■ Prophase: ■ M_____________: ■ A______________: ■ T______________; c) cytokinesis: 2) Compare the processes and outcomes of mitosis and meiosis. Mitosis (Ouch!: My TOE sis!) Meiosis Functions: Makes somatic (body) cells _________________ reproduction Growth and repair (healing) Makes _____________ (egg and _______) Sexual reproduction Produces: Identical daughter cells / have the same number of chromosomes 4 haploid daughter cells Creates variation One round of division _______ rounds of division Does NOT separate homologous chromosomes 3) Explain how genetic information is inherited. DNA Why is it Important? ● DNA genetic material passes from generation to generation. ● DNA controls cellular activities by controlling the production of proteins and enzymes ● DNA determines an organism’s traits. ● DNA holds the information for life. ● Describe the process of DNA replication and how it transmits and conserves genetic information. Explain the functional relationships between: ● DNA ● genes ● alleles ● chromosomes 4) Describe and/or predict observed patterns of inheritance ● dominant: ● recessive: ● co-dominance: both allele’s phenotypes (traits) are expressed (ex: roan cow = red and white ) ● incomplete dominance: ● sex-linked: a gene on the X (sex) chromosome, males more likely to have a sexlinked disease, as they only have 1 X, females have 2 Xs (one can be backup) ex: hemophilia or color blindness ● polygenic: trait influenced by many genes (poly means many ex: skin color, height) ● multiple alleles: More than two alleles for a single gene. Ex: Blood type: i, IA; IB 5. Describe processes that can alter composition or number of chromosomes: crossing-over, nondisjunction, duplication, translocation, deletion, insertion, and inversion. 5. Explain the process of protein synthesis: 1. transcription : Copying _________ in the nucleus and making _____________. Enzyme: RNA __________________ (makes the RNA polymer). 2. translation: Ribosomes make ___________________ in the cytoplasm and on the RER. 3. protein modification in golgi: protein is finished and packaged for transport Protein Synthesis Machinery Role in protein synthesis of secreted proteins Pro/Euk/both ribosome Endoplasmic reticulum golgi apparatus nucleus DNA/gene 6. Describe how genetic mutations alter the DNA sequence and may or may not affect phenotype ● silent: Does not change the ___________ acid ● nonsense: creates a stop codon ● frame-shift: insertion or _______________ that changes the “reading frame” (all the codons are shifted) 7. Exp l ain how genetic engineering has impacted the fields of medicine, forensics, and agriculture ● selective breeding: we breed traits we like into cows, horses, dogs, vegetables and fruit, etc. and get different breeds/strains with different phenotypes. ● gene splicing : we can move genes from organism to organism. ● cloning: we create identical copies of organisms for research and developing medicines ● genetically modified organisms: food crops like corn and wheat are modified to resist pesticides ● gene therapy : we correct genetic mutations in the person instead of using drugs 8. Explain the mechanisms of evolution. ● Explain how natural selection can impact allele frequencies of a population. ❖ Favorable (advantageous) alleles are selected for = allele frequency increases!! ❖ unfavorable alleles are selected AGAINST = allele frequency _______________!! ● Describe the f actors that can contribute to the development of new species : i. ii. isolating mechanisms (prevent reproduction! ) 1. geographical barriers like a _____________ or ____________ prevent mating. 2. behavioral: song, dance, flashes of light , etc., that signal to mates is different. 3. temporal (time): different species mate at different times. ex: Eastern and western skunks genetic drift: random chance affecting SMALL populations 1. example : founder effect small group of people start a colony Amish 2. example: bottleneck disaster kills most of the population, only small group survives Northern sea lions (humans hunted them almost to extinction) iii. migration individuals move to a new area with different environmental pressures ● Explain how genetic mutations may result in genotypic and phenotypic variations within a population. Mutations create variation in alleles! New traits like red hair. 9. Evidence supporting the theory of evolution: ★ fossils ★ anatomical (anatomy like the homologous forelimbs) ★ embryological: all vertebrate embryos look the same, and develop in the same way gill slits! ★ biochemical ex: all organisms do glycolysis burn glucose the same way! ★ universal genetic code: all organisms use the same genetic code. 10. Describe ecological levels of organization ● organism ● population ● community ● ecosystem ● biome ● biosphere 11. Describe characteristic biotic and abiotic components of aquatic and terrestrial ecosystems. Desert: Rainforest: Grassland: Deciduous Forest: Tundra: 12. Describe interactions and relationships in an ecosystem. ● Describe how energy flows through an ecosystem ○ food chains: producers to consumers ○ food webs: food chains connected ○ energy pyramids (remember the 10% rule) ● Describe biotic (living) interactions in an ecosystem ○ competition : examples: competition for food, mates, nesting sites ○ predation: ex.:lynx and arctic hare ○ symbiosis parasitism example: ticks, fleas, tapeworm benefit, host is harmed commensalism :: barnacles on whales get more food, but don’t affect the whale mutualism, ex: pollinators and flowers help each other ● Describe how matter recycles through an ecosystem: water; carbon cycle/oxygen cycle; nitrogen cycle Describe how ecosystems change in response to natural and human disturbance s ○ climate changes ○ introduction of nonnative species ○ pollution ○ fires Describe the effects of limiting factors on populations and potential species extinction. Limiting factors (control population size): ● food ● space for nesting/homes ● water ● competition ● predation ● disease