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Endocrine Control of the Lacrimal Gland Eduardo M. Rocha Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, FMRP-USP Lacrimal gland structure and function are regulated by hormones; therefore hormone dysfunction may affect not just tears production and ocular surface maintenance but also inflammatory behavior and capacity to respond to trauma or environmental conditions. Diseases like diabetes mellitus, hypothyroidism or others related to sex hormones cause dry eye syndrome. The mechanisms of hormone action over lacrimal and ocular surface and potential use of hormones in diagnosis and treatment of dry eye syndromes will be addressed. Support: CNPq, FAPESP, FAEPA Eduardo M. Rocha Depto. de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço Faculdade de Medicina de Ribeirao Preto - FMRP-USP http://www.fmrp.usp.br/