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Transcript
Energy Metabolism Transformations and Interactions Absorption To Blood system To lymphatic system 1 Metabolic Processes Fuel (Carbohydrates, (Carbohydrates Lipids Lipids, Proteins) Metabolism – Transfer of food energy and nutrients into form that cells can use Maintenance – repairing i i body b d parts and keeping organs functioning Adenosine Triphosphate - ATP ADP AMP ATP 2 Reactions – Energy Common metabolic block Acetyl CoA O CH3 C S C A CoA 3 Metabolic Reactions Anabolism – Reactions that build complex molecules from small one Anabolism 4 Glycogenesis Metabolic Reactions Catabolism – Reactions that break down compounds into small units 5 Catabolism Glycogenolysis 6 Nutrients & Energy Metabolic processes producing energy: Glycolysis Glucose Pyruvate Acetyl CoA TCA (Tricarboxylic Acids) cycle Electron transport chain Intermediates Glucose yields energy Glycolysis y y 7 Glucose The fate of pyruvate – Anaerobic vs. aerobic pathways Glucose The fate of pyruvate Anaerobic Pyruvate to lactic acid –Cori cycle 8 Pyruvate to Lactic Acid (Anaerobic) Cori Cycle Glucose The fate of pyruvate Aerobic Pyruvate to acetyl CoA 9 Pyruvate to Acetyl CoA (Aerobic) Energy balance from glucose aerobic metabolism 10 Fatty Acids to Acetyl CoA Fats Enter the Energy Pathway β β-Oxidation 11 The Carbons of a Typical Triglyceride Glycerol Fatty acids 18 C 18 C 18 C 3C 54 C 27 Acetyl CoA Energy balance from fat aerobic metabolism 27 54 81 27 180 Acetyl CoA 27 Acetyl CoA from C18:1 TG Fat 12 Amino Acids Many amino acids are transferred into glucose Glucogenic Some amino acids are Directly transferred into acetyl CoAKetogenic Some amino acids can enter directly TCA cycle Glucogenic Amino Acids Deamination Amino acids synthesis – Keto acid – Ammonia 13 Amino Acids Ammonia to urea Urea excretion via kidneys 14 The Sources of Pyruvate and Acetyl CoA Glutamic Acid Arginine Histidine Glutamine Proline Alanine Cysteine Glycine Serine Threonine β-oxidation Phenylalanine Tyrosine Leucine Lysine Tryptophan 15
