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Transcript
BIO 245: Principles of Genetics
Course description
BIO 245. PRINCIPLES OF GENETICS. An overview of the principles of plant
and animal genetics including Mendelian and modern concepts of heredity.
Developments in molecular genetics will be addressed through the chemistry
and physiology of the gene and the nature of gene action in prokaryotic and
eukaryotic cells. Three 50-minute lectures per week and 3 hours of laboratory
per week. Prerequisites: BIO 141-142 and two semesters of college
mathematics (MAT 142, MAT 143 or higher level) or equivalent. Offered in fall
semesters on the St. Thomas campus only.
Goals & Objectives
- Goal #1: To learn and apply concepts of modern transmission and molecular
genetics.
o Objective 1A: To identify and describe the process and purposes of
the cell cycle, meiosis, and mitosis, as well as predict the outcomes of
these processes.
o Objective 1B: To solve transmission genetics problems, make
accurate predictions about inheritance of genetic traits, and map the
locations of genes.
o Objective 1C: To identify the parts, structure, and dimensions of DNA
molecules, RNA molecules, and chromosomes, and be able to
categorize DNA as well as describe how DNA is stored.
o Objective 1D: To accurately diagram and describe the processes of
replication, transcription, translation, as well as predict the outcomes
of these processes.
o Objective 1E: To describe what causes and consequences of DNA
sequence changes and how cells prevent these changes, as well as
make predictions about the causes and effects of changes in DNA.
o Objective 1F: To describe the processes of gene regulation and
predict how a gene will be expressed under specific circumstances.
- Goal #2: To learn and practice common genetics laboratory and field
techniques.
o Objective 2A: To describe applications and techniques of modern
genetic technology, as well as select the correct techniques to solve
practical genetic problems.
o Objective 2B: To carry out genetics laboratory and field research
techniques.
o Objective 2C: To describe experimental results in written format both
informally and in formal manuscript format.
Topics covered
- Inheritance
o Mitosis & meiosis
o Mendelian genetics
o Genetics of sex
o Extensions of Mendelian genetics
- Molecular genetics
o DNA structure
o DNA replication
o DNA transcription
o RNA translation
o Genes & proteins
- Gene mapping
-
-
o Linkage & eukaryotic gene mapping
o Bacterial gene mapping
Biotechnology
Genomics
Gene regulation (prokaryotic & eukarotic)
Mutation
o Mechanisms & repair
o Chromosomal mutations
o Cancer
Transposable elements
Population genetics