Download biology 377

Immunology
Biology 377
California State University-San Marcos
Syllabus
Semester: Fall 2008
Lecture: Tues/Thurs 10:30-11:45
Lecture location: Markstein 306
Instructor: Dr. Jennie C. C. Chang
Office hours: Thurs 12:00-2:00 pm
Location: SCI2, Rm141
email: [email protected]
(email is the best way to contact me)
On-line posting of lecture notes: Go to Yahoo.com, click on mail, “id” to log in is
[email protected], password is “csusm377”
Check this website for lecture notes and notices about the course.
Textbook:
Required
Kuby Immunology by Richard A. Goldsby, Thomas J. Kindt, Barbara A. Osborne (2007) W.H. Freeman 6th Ed.
http://bcs.whfreeman.com/immunology6e/
Optional
Case Studies in Immunology by Fred Rosen and R. Geha (2007) Garland Science 5th Ed
http://www.bios.co.uk/textbooks/0815341451.asp
Course Objectives:
 Nature and components of innate immunity
 Cells and functions of adaptive immunity
 Genes involved in immunity
 Immune dysfunctions (e.g., autoimmunity), immune functions in infection, cancer and transplantation
Grading policy:
Exam 1
Exam 2
Exam 3
Report
3 Quizzes
Class participation/attendance
Total
100 pts
100 pts
200 pts
100 pts
90 pts (30 pts per quiz)
30 pts
620 pts
Final grade assignments:
A = 93-100%
A- = 90-92%
B+ = 87-89%
B = 83-86%
B- = 80-82%
C+ = 77-79%
C = 73-76%
C- = 70-72%
D = 60-69%
F = < 60%
1
Exams will consist of multiple choice, short answer and essay questions. Make-up exams must be arranged
prior to the scheduled exam period. The final examination may not be changed unless approved by the Dean of
the College of Arts and Sciences. No make-up final examination will be given except for reasons of illness or
other verified emergencies.
The report will consist of a 6-8 page paper (1200-1600 words, 12 pt font, double spaced) on a topic of your
choice from the Case Studies in Immunology book. To clarify, you can pick a subject from the Case Studies
book which we will not cover in class. Give me your preferred topic by Oct. 21, report is due Dec. 4.
Attendance: Students can earn a bonus on their total points of 30 points for perfect attendance. (Each absence
= 10 points less, each late = 5 points less). Although there are times when missing class cannot be helped, these
extra credit points are only for perfect attendance. No excuses for bonus points. Stay healthy.
Add/drop class: Students should go to the Express Center (located in CRA 4701). The Center is open from 8
am to 6 pm through the last day of add/drop – September 8, 2008.
Absence for the 1st or 2nd class results in administrative drop. Excessive absence in the first 4 weeks also results in
administrative drop.
Classroom Rules: No talking will be allowed during class. A warning will be given for the first offence, and
if it continues, the student will be asked to leave the classroom. Cell phones should be off during class.
Plagiarism policy: Any evidence of cheating will result in a failing grade for that assignment and possibly a
failing grade for the semester for the course. Please see me if you have any questions about what exactly
constitutes plagiarism.
Schedule of material to be covered in lectures and exams:
DATE
Topics and Chapters covered
Week 1
Aug 26
Aug 28
Introduction, history of immunology
Body’s defense system, innate immunity
Week 2
Sep 02
Sep 04
complement system, tissue of the immune system
Immunoglobulin structure & function
Week 3
Sep 9
Sep 11
Immunoglobulin structure & function, continued
Quiz #1; B cell development
Week 4
Sep 16
Sep 18
B cell development, continued
MHC
Week 5
Sep 23
Sep 25
MHC, continued
Group discussion, review
2
Week 6
Sep 30
Oct 2
Exam 1
T cell antigen receptor
Week 7
Oct 7
Oct 9
Antigen processing
Antigen processing, continued; T cell repertoire
Week 8
Oct 14
Oct 16
T cell repertoire and self-tolerance
Quiz #2; Super antigens
Week 9
Oct 21
Oct 23
cytokines; Report topic due
Killer cells
Week 10
Oct 28
Oct 30
Group discussion, review
Exam 2
Week 11
Nov 04
Nov 06
Hypersensitivity, blood transfusion
Autoimmunity, Immunodeficiency
Week 12
Nov 11
Nov 13
Week 13
Nov 18
Nov 20
Week 14
Nov 25
Nov 27
Week 15
Dec 02
Dec 04
Week 16
Tues, Dec. 9
No class: Veteran’s Day
Infectious diseases and immunity
Quiz #3; Cancer immunity
Transplant immunology
The immune system in health and disease continued
Immunological methods
No class, Thanksgiving holiday
Vaccine development; Report due
Review
Final (comprehensive) Examination
3