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Transcript
MATHEMATICAL TALES OF A SPERM TAIL
Hermes Gadelha1,2,
1
Wolfson Centre for Mathematical Biology,
Mathematical Institute, University of Oxford, Oxford OX2 6GG, UK
[email protected]
2
Centre for Human Reproductive Science,
University of Birmingham, Edgbaston Birmingham B15 2TT, UK
Abstract
Active cell motility via the controlled movement of a flagellum beating is among
the phylogentically oldest forms of motility, and has been retained in higher level
organisms for spermatozoa transport. Despite this ubiquity and importance, the
details of how the flagellar waveform emerges from the underlying mechanics and
how the cell, or the environs, may control the beating pattern by regulating the
flexible tail is far from fully understood. We demonstrate in this talk that mechanics and modelling can be utilised to interpret observations of flagellar dynamics,
swimming trajectories, beating patterns, as well as unexpected phenomena associated with their complex material response. It also highlights that this is a fertile
and challenging area of inter-disciplinary research for applied mathematicians and
demonstrates the importance of future observational and theoretical studies in understanding the underlying mechanics of these motile cell appendages.