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Overview Table Level 4 Title / Scientist(s) Page Idea and evidence Vocabulary / Resources Science Terminology No. Matching topics in KS3 Science / KS4 Biology (S4-6) 4-9 Working out the structure of • DNA In 1953, two young scientists, James Watson and adenine Worksheet 1 KS3 Science (S1-3) 3.2 Heredity Francis Crick succeeded in building an accurate model thymine guanine - James Watson (1928 - ) explain how DNA replicates itself and how DNA cytosine characteristics - Francis Crick (1916 - 2004) determines body characteristics. double helix KS4 Biology (S4-6) In putting together the pieces of the DNA puzzle, base pairing II. Genetics and Watson and Crick used the findings of various X-ray crystallography Evolution scientists. Erwin Chargaff’s findings had helped solve X-ray diffraction b. Molecular genetics • 10-15 Mendel – the first person to • CD Track X1 - Inheritance of of the DNA molecule. This model enabled them to the issues of base pairing, and Rosalind Franklin and - Chromosomes, genes Maurice Wilkins had provided useful data for the and nucleic acids arrangement of different chemical groups in DNA - DNA technology and molecules through X-ray crystallography. DNA fingerprinting When Mendel crossed a pure-breeding tall plant with a pure-breeding Worksheet 2 KS3 Science (S1-3) study inheritance pure-breeding short plant, the first generation offspring offspring 3.2 Heredity scientifically produced were all tall. But when those offspring was contrasting character CD Track X2 - Inheritance of self-crossed to produce a second generation, most of generation characteristics © Times Publishing (Hong Kong) Limited -1- - Gregor Mendel (1822-1884) • the second-generation offspring were tall, but a hereditary factor KS4 Biology (S4-6) smaller number were short. gamete II. Genetics and Mendel explained through the first law of inheritance Mendel’s first law of Evolution that a pair of hereditary factors controls the inherited features of an organism. During gamete formation, inheritance a. Basic genetics chromosome - Medal’s laws of separation of each pair of hereditary factors occurs inheritance and each gamete receives one factor from each parent. 16-22 What did Darwin learn from • the finches? - Charles Darwin (1809-1882) On the Galapagos Islands, Darwin found some animal specimen and plant specimens that were similar to those from finch the mainland. He studied the finches, the iguana and iguana giant tortoises there and found significant variations evolution - Variation within the that were specific to the species from each island. natural selection same kind of living Based on his observations, Darwin came up with an Worksheet 3 KS3 Science (S1-3) 2.2 Observing an animal CD Track X3 2.3 Diversity things idea of how evolution worked by natural selection. He explained why the finches found in the Galapagos KS4 Biology (S4-6) Islands had different beaks and were adapted to eat II. Genetics and different foods available on the islands, using his Evolution theory of natural selection. c. Biodiversity and evolution © Times Publishing (Hong Kong) Limited -2-