Download Chapter 16: The Molecular Basis of Inheritance

DNA Discovery and Structure
1. A number of historically important scientists and experiments are presented under this topic.
For each scientist or team of scientists give the following information:
a) A short, but complete description of their historical experiment or discovery.
b) An explanation on how their work contributed to our understanding of the molecular basis of
inheritance.
Scientists:
Avery, McCarty and MacLeod; Hershey and Chase; Chargaff; Watson and Crick; Franklin
and Wilkins
2. A particular organism’s DNA is found to be 19% Adenine. What are the values of the other
DNA bases for this organism?
3. Explain why DNA replication is described as “semi-conservative”.
4. Discuss the key points of the DNA molecular structure. You may use a diagram to
SUPPLEMENT your answer.
5. Create a review table that identifies the key enzymes and proteins that are involved with DNA
replication and describes each molecule’s function or purpose.
6. Contrast and compare DNA replication on the leading and lagging strands.
7. Describe a chromosome telomere and its possible function(s).
Readings:
Campbell 7th edition Chapter 16
Mader Chapter - 12
OpenStax – Chapter 14
Bozeman Biology
What is DNA?
https://www.youtube.com/watch?v=q6PP-C4udkA
DNA and RNA – Part 1
https://www.youtube.com/watch?v=qoERVSWKmGk
DNA and RNA – Part 2
https://www.youtube.com/watch?v=W4mYwsr9gGE
The Double Helix
http://www.hhmi.org/biointeractive/double-helix
MIT - OpenCourseWare
DNA Structure and Classic Experiments – Eric Landers
https://www.youtube.com/watch?v=P-Ry4rRdDbk
DNA Structure and Classic Experiments – Eric Landers
https://www.youtube.com/watch?v=YCeKtM6Hnmc