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4/11/2016
Baton Rouge Community College
Academic Affairs Master Syllabus
Date Approved:
Course Name:
Registrar:
Lec-Lab-Credit:
Fundamentals of Genetics
BRCC Course Rubric:
2016: BIOL 2514
Prior to 2016:
Lecture:
Contact Hrs/Wk:
Credit Hours:
5 May 2016
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3-3-4
State Common Course Rubric: CBIO 2514
Lab:
Contact Hrs/Wk:
Credit Hours:
CIP Code 26.0801
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Course:
Contact Hrs/Term
Credit Hours:
90
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Course Description: Covers general principles of genetics, to include heredity and genetic
analysis. The course material is presented in a combined lecture and laboratory format.
Prerequisites:
BIOL 1033 (or BIOL 120) and BIOL 1031
(or BIOL 120L) with a grade of “C” or better
Co-requisites:
None
Suggested Enrollment Cap:
24
Learning Outcomes: Upon successful completion of this course, the students will be able
to:
1. Demonstrate knowledge of genetic principles and problem solving skills.
2. Relate an organism’s genotype to its phenotype.
3. Explain basic techniques used for genetic manipulation and procedures used to identify
genome structure and gene function.
4. Analyze the genetic structure of a population.
5. Explain how genetics plays a role in society.
Assessment Measures: Assessment of all learning outcomes will be measured using the
following methods:
1. Administration of unit exams during the semester and a comprehensive final exam at the end
of the semester.
2. Instructor-designed assignments, including but not limited to, laboratory reports, projects,
homework and/or quizzes. All will be graded using an instructor-designed rubric.
Information to be included on the Instructor’s Course Syllabi:

Disability Statement: Baton Rouge Community College seeks to meet the needs of its
students in many ways. See the Office of Disability Services to receive suggestions for
disability statements that should be included in each syllabus.

Grading: The College grading policy should be included in the course syllabus. Any
special practices should also go here. This should include the instructor’s and/or the
department’s policy for make-up work. For example in a speech course, “Speeches not
given on due date will receive no grade higher than a sixty” or “Make-up work will not
be accepted after the last day of class.”

Attendance Policy: Include the overall attendance policy of the college. Instructors may
want to add additional information in individual syllabi to meet the needs of their
courses.

General Policies: Instructors’ policy on the use of things such as beepers and cell phones
and/or hand held programmable calculators should be covered in this section.

Cheating and Plagiarism: This must be included in all syllabi and should include the
penalties for incidents in a given class. Students should have a clear idea of what
constitutes cheating in a given course.

Safety Concerns: In some programs this may be a major issue. For example, “No
student will be allowed in the safety lab without safety glasses.” General statements such
as, “Items that may be harmful to one’s self or others should not be brought to class.”

Library/ Learning Resources: Since the development of the total person is part of our
mission, assignments in the library and/or the Learning Resources Center should be
included to assist students in enhancing skills and in using resources. Students should be
encouraged to use the library for reading enjoyment as part of lifelong learning.
Expanded Course Outline:
I. Introduction to Genetics
II. Patterns of Inheritance
A. Mitosis and Meiosis
a. Cell structure and genetic function
b. Roles of mitosis and meiosis in multicellular organisms
c. Gametogenesis
B. Mendelian Genetics
a. Simple patterns of inheritance
b. Mendel’s Laws of Segregation and Independent Assortment
c. Laws of probability
d. Chi-square analysis
e. Pedigrees
C. Modifications to Medelian Ratios
a. Deviations from Mendel’s observations
b. Sex linked, sex limited and sex influenced inheritance
c. Extranuclear inheritance
D. Sex Determination and Sex Chromosomes
a. Genetics of sex determination in different organisms
b. Dosage compensation
E. Chromosomal Mutations
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a. Nondisjunction
b. Monosomies and Trisomies
c. Polyploidy
d. Chromosomal mutations: deletions, insertions, duplications, inverstions,
translocations and fragile sites
F. Linkage and Gene Mapping
a. Gene linkage
b. Crossing over
c. Linkage maps
III. Molecular Genetics
A. DNA Structure and Analysis
a. Characteristics of genetic material
b. Structure and function of DNA
c. Alternative forms of DNA
d. Structure of RNA
B. DNA Replication and Chromosome Structure
a. Models of DNA replication
b. Prokaryotic chromosome structure and DNA replication
c. Eukaryotic chromosome structure and DNA replication
C. The Genetic Code and Transcription
a. Nature of the genetic code
b. Molecular process of transcription
c. RNA editing
D. Translation and Proteins
a. Types of RNA involved in translation
b. Three steps of translation
c. One gene - one polypeptide hypothesis
d. Relationship of proteome and phenotype
c. Protein modification
E. Mutagenesis and Gene Repair
a. Types of mutations
b. Effects of mutations
c. DNA repair mechanisms
F. Regulation of Gene Expression
a. Prokaryotic gene expression
b. Eukaryotic gene expression
G. Cell Cycle Regulation and Cancer
a. Definition of cancer
b. Genetics of cancer
c. Environmental effects contributing to cancer
IV. Molecular Genetic Tools
A. Recombinant DNA Technology
a. Definition of recombinant DNA
b. PCR and its uses
c. DNA libraries and their uses
d. Cloning
e. DNA sequencing
B. Genomics and Proteomics
a. Definition of genomics
b. Functional genomics in prokaryotes and eukaryotes
c. Comparative genomics in prokaryotes and eukaryotes
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d. Proteomics
C. Applications and Ethics of Genetic Engineering
a. Genetic engineering in agriculture, pharmaceuticals, medicine and forensics
b. Ethical, social and legal questions raised by genetic engineering
V. Genetic Analysis of Individuals and Populations
A. Developmental Genetics
a. Model organisms and developmental genetics
b. Segment formation, homeotic genes and gene cascades
c. Plant developmental systems
B. Quantitative Genetics
a. Polygenic traits
b. Statistical analysis
c. QTL mapping
C. Population Genetics
a. Hardy-Weinberg Law and its uses
b. Natural selection, mutation, migration, genetic drift, non-random mating
and their effects on populations
D. Evolutionary Genetics
a. Speciation
b. Reconstruction of evolutionary history
E. Conservation Genetics
a. Genetic diversity and conservation genetics
b. Causes of the erosion of genetic diversity
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