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Ms. Bruno DNA Regents Biology Name __________________________________________________________ Date ______________ Per _______ DNA: The Code of Life! DNA is the molecule that contains all of the ________________ material for an organism It is found ONLY in the _______________ of eukaryotic cells DNA is also a _____________ __________, which means it is composed of thousands of subunits called ______________________ Each nucleotide in DNA consists of 1. 2. It’s a Double Helix! 3. In ________, Dr. James ______________ and Dr. Francis ______________ developed a model of the DNA molecule that showed DNA is a “double helix,” or a ___________________ ______________ Composition of the Ladder: The __________ of the “ladder” are formed by a backbone of ___________________ and _____________________ molecules Meet the Nitrogenous Bases! The nitrogenous bases that make up the “rungs” of the DNA ladder are: ____________________ (A) ____________________ (T) ____________________ (C) The “____________” consist of 2 nitrogenous ___________ joined together in the middle by _____________________ bonds ____________________ (G) These bases are the “letters” that spell out the _________________ code Ms. Bruno DNA Regents Biology Base Pairing: __________ bases (a pair) make up each “___________” of the DNA ladder In base pairing: Adenine always pairs with _________________ (A-T) Cytosine always pairs with _________________ (C-G) The Formation of DNA: To make DNA, ________________________ are joined together in long, continuous __________________ of nucleotide building blocks ____________ DNA strands bind _________________________ to form the “double” helix The binding of two DNA strands to each other requires that the bases pair in a very ___________________ and ______________________ manner Complimentary Strands! An _______ on one strand means that the _________________ strand must contain a _______ at the same position ATGCCAATGGGATC A ________ on one strand means that the opposite strand has a ________at the same ___________________ In this way, the strands are said to be ________________________! Practice Problem: A strand of DNA has 100 bases. Thirty-five of these bases are adenine. How many bases are cytosine? Ms. Bruno DNA Regents Biology DNA Replication: To _____________________ the genetic material, the two strands of DNA are _______________________ one base at a time and a __________ strand of DNA is made using the _DNA literally unwinds and “unzips” along the weak hydrogen bonds that hold the base pairs together Once the DNA “_____________,” free ______________________ floating in the _____________________ pair with the “free” bases of both DNA strands Because the ____________________________ bases can only pair in one way (_____________________________________), two new _________________ strands of DNA are formed These two new strands are ____________________ to each other and the original DNA molecule strand