Download DNA Origami

David W. Grainger
Nature Nanotechnology 4, 543 - 544 (2009)
Speaker：Zong-Han Li
Instructor: Kun-Mao Chao
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DNA Origami
Surface patterning with DNA tiles
DNA tiny chips
Geometrical self-assembly
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A: single-stranded
DNA and staple
strands.
B: Design of a selfassembled DNA
origami structure
and geometry of
the incorporated
double-stranded
DNAs.
Endo, M. and Sugiyama, H. 2011.
Recent Progress in DNA Origami Technology.
Current Protocols in Nucleic Acid Chemistry. 45:12.8.1–12.8.19.
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a:Nanoscale
DNA tiles
b:DNA tiles
decorated with
different functional
reagents are used
to create a variety
of functional
devices from a
mixed solution of
tiles.
David W. Grainger
Nature Nanotechnology 4, 543 - 544 (2009)
doi:10.1038/nnano.2009.249
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R. J. Kershner et al
6nm
Nature Nanotechnology 4, 557 - 561 (2009)
DNA Origami for Faster, Smaller Computer Chips
IBM suggests that it could take up to
10 years to test and refine the process
for manufacturing.
Tiny, triangular DNA structures self-assemble on silicon.
Credit: IBM
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Attractive interactions between DNA origami tiles are coded in their
complementary shaped edges, recapitulating the binding of
complementary sequences of bases to form a DNA double helix.
DNA nanotechnology: Geometrical self-assembly
Andrew J. Turberfield
Nature Chemistry 3, 580–581 (2011)
doi:10.1038/nchem.1097
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