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Download Pedigree Problems 1. The pedigree shows the pattern of inheritance
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Pedigree Problems 1. The pedigree shows the pattern of inheritance for a rare human disease. Filled symbols indicate individuals with the disease; open symbols indicate normal individuals. (a) What is the most probable mode of inheritance (dominant or recessive) for this trait? (b) What is the most convincing evidence you can give for your answer to (a)? (c) What are the most probable genotypes of individuals II-I and II2? (d) If individuals II-6 and II-7 have another child, what is the probability that it will be normal? 2. The following pedigree shows the pattern of inheritance for a rare human disease. Filled symbols indicate individuals with the disease: open symbols indicate normal individuals. (a) What is the most probable mode of inheritance (dominant or recessive) for this trait? On what do you base your answer? (b) What are the most probable genotypes of individuals I-1 and I2? (c) What are the most probable genotypes of individuals II-9 and II10? (d) If individuals II-1 and II-2 have another child, what is the probability that it will have the disease? 3. In the following hypothetical pedigree, there are two traits considered. One gene determines if a person is a vampire or not; the other gene determines if a person is a werewolf or not. The two genes sort independently. Study the diagram then answer the questions below. (HINT: Examine each trait separately when working out the genotypes.) (a) Is being a vampire due to a dominant or recessive allele? How can you tell? (b) Is being a werewolf due to a dominant or recessive allele? How can you tell? (c) Give the most likely genotypes for individuals I-2, II-3, and II-6. Use D and d for the alleles of the vampire gene and R and r for the alleles of the werewolf gene.