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Biology 12 Nervous System 1. What are the two basic regions of the Central Nervous System? 2. Name the two basic subdivisions of the Peripheral Nervous System. 3. Make a diagram that clearly discriminates the following regions of the spine: cervical, thoracic, lumbar, & sacral. 4. What is meant by each of the following: a. cranial nerve b. spinal nerve c. peripheral nerve 5. You have completely severed your nerve cord between the 4th and 5th cervical vertebrae. Explain the consequences of this injury. 6. What is the difference between a nerve and a neuron (nerve fiber)? Nerve will be composed of multiple sensory neurons and motor neurons 7. Using the diagram given to you, clearly colour, label, and five the functions of the following parts of the brain: Medulla oblongata* Hypothalamus* Pons* Cerebellum* Meninges Corpus callosum* Thalamus* Anterior pituitary* Posterior pituitary* Cerebrum (showing the four lobes) 9. What is the function of the somatic nervous system? …autonomic? You have entered into a ‘fight or flight’ situation (stress situation). Show your understanding of how the Autonomic N.S. is involved by answering or completing the following. 10. a. Name those organs considered to be ‘fight or flight’ organs. heart, lungs, brain, liver, and kidney b. Name those organs considered to be ‘relaxed state’ (day to day operations) organs. stomach, intestines, heart 2 11. Copy the following table onto your answer sheet and fill in with the correct words. Neurotransmitter Effect on ‘fight or flight’ organs (excite or inhibit) Effect on relaxed state organs (excite or inhibit) Sympathetic Norepineprhine Parasympathetic Acetylcholine excite inhibit inhibit excite 12. Why do you suppose that each system (parasympathetic and sympathetic) must have its own type of neurotransmitter? They have different functions… 13. In certain (stressful) circumstances individuals have been known to perform significant feats of strength. Outline in point form and in proper sequence, the events that would occur as a response to both the nervous system and the endocrine (hormonal) system stimulation (or inhibition). Start with a sensory input and the effect first on the nervous system and end with the person doing some incredible feat. You must include adrenalin and its role in the response. How does this physical response enable the person to be stronger than normal? It will allow for more ATP to be produced…more energy available 14. Sketch a sensory neuron. Label and provide a function for each of the following. A. Dendrite E. Cell membrane I. Schwann cell B. Cell body F. Axon C. Node of Ranvier G. Axon bulb D. Myelin sheath H. Receptor 15. Observe the reflex arc below. Name each of the sites indicated by the numbers. 1. sensory receptor 2. Node of ranvier 3. cell body 3 4. Synapse 5. Interneuron 6. Axon Terminal 7. Cell Body 8. Myelin sheath 9. Muscle (effector) 16. Give the basic role of each of the following kinds of neurons. a. sensory b. interneuron c. motor 17. Outline the major steps of a reflex arc, starting with detection of a stimulus by the receptor of the sensory neuron. Sensory dendrite perceives impulse…dendrite to cell body to axon to dendrite, cell body and axon of interneuron and finally to the dendrite , cell body, and axon of the motor neuron. This will stimulate the effector (muscle or gland) 18. At the first step of the reflex arc above, the following measurements were made at the sensory neuron, and placed in a graph form. Explain what is occurring between/at; A. point A B. point B C. point C D. point D E. point E C. Depolarization D. Repolarization B. Threshold E. Resting potential A. Resting potential 4 19. A sensory neuron has a long dendrite and a short axon, a motor neuron has a short dendrite and a long axon. Where would that place the cell body of each type of neuron near and why is this placement significant? The cell bodies are located in the spinal column…for protection 20. For each of the following points of an action potential give its meaning, its cause and its value in mV. Ie) explain the ion concentrations or what is happening i) resting potential…more sodium outside, more potassium inside ii) upswing (depolarization)…voltage regulated sodium channels open and sodium rushed in…this causes positive ions to repel and propel down the axon length iii) downswing (repolarization). voltage potassium channels open and potassium leaves cell iv) recovery…active transport using a sodium/ potassium pump to re-establish the concentration gradient Create diagrams of the neuron at each stage. Show significant ions and there relative distribution. Also draw in and label the manner in which the ions move from one side of the membrane to the other. 21. What is the significance of having mylinated fibers? Explain what is meant by saltatory conduction. It prevents the ions from leaking out and slowing down the impulse 22. Study the diagram below. a. Copy out the diagram and label each of the letters. W- dendrite X- Synapse Y- axon terminal Z- Vesicles containing neurotransmitter b. Label each of the following on the diagram. i) presynaptic membrane ii) postsynaptic membrane 5 c. For impulse transmission explain: i) the role of Ca+2 Binds to the vesicle to assist the vesicle to bind to pre-synaptic membrane ii) the movement of neurotransmitter vesicles and of neurotransmitter once released…move to the membrane…exocytosis and then they diffuse across gap iii) the effect of inhibitory and excitatory neurotransmitters on the dendrite (summation and the all or none law). Once the neurotransmitter binds to the receptor proteins on the post-synaptic membrane they trigger sodium to rush in if it is an excitory neurotransmitter, If enough sodium (threshold) reaches the axon hillock (summation) the nerve impulse will be carried..if not it wont (all or none). If the neurotransmitter is an inhibitory molecule it will cause potassium to leave which lowers the resting potential and inhibits any action iv) the significance of “threshold” The amount of sodium that comes in must raise the potential difference to -55mV or the action potential will not be carried v) how neurotransmitters are removed from the synaptic cleft (2 possibilities). Specifically explain the role of acetylcholinesterase. The neurotransmitters can diffuse away or back into the pre-synaptic membrane or the enzyme acetylcholinesterase can be used to break down acetylcholine 23. Observe the diagram below. Neuron 2 was exposed and then stimulated at point X using an electrode. Explain what would occur between the following points (depolarization or not). A. B. C. D. E. point X & point B…the area could be depolarized and action potential carried point B & point A…nothing as the dendrite does not have neurotransmitters point X & point C…action potential point C & point D…crosses the synapse using neurotransmitters Why is nerve impulse transmission only one way? the structure of the axon terminal is meant for sending messages to the dendrite not sending and vice versa