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NOTES Endocrine System Endocrine System Roles of the Endocrine System • glands that produce chemicals (hormones) released into the blood • General role: > Maintain homeostasis > Regulate growth and development > Coordinate energy use Regulate response to stim 1 NOTES Endocrine System Types of Hormones • 1. Amines: Examples: epineprine and thyroid hormones • 2. Prostaglandins: act as chemical messengers, but do not move to other sites • 3. Steroid hormones: Examples: testosterone and estrogen • 4. Peptide and Protein hormones: are the largest and most complex hormones. Example: insulin. Glands and Hormones 2 NOTES Endocrine System Hormones • found in plants as well • In humans: maintain conditions in the body > > > > > Temperature pH Water balance Growth Development • The hormone travels to a specific site: the target cells have receptors on them for this purpose • Hypothalamus Gland: > lower central part of the brain > regulation of satiety, metabolism, and body temperature > secretes hormones that control the pituitary gland. > Ex somatostatincauses the pituitary gland to stop the release of growth hormone. 3 NOTES Endocrine System • Pituitary Gland: • base of the brain, no larger than a pea • control many functions of other endocrine glands > The anterior lobe – – – – Growth hormone Thyroidstimulating hormone (TSH) Adrenocorticotropin hormone (ACTH) Luteinizing hormone (LH) and folliclestimulating hormone (FSH) control sexual function and production of the sex hormones – Prolactin stimulates milk production in females > The posterior lobe – Antidiuretic hormone Controls water loss by the kidneys – Oxytocin Contracts the uterus • Pineal Gland: > middle of the brain > Melatonin: regulate the wakesleep cycle 4 NOTES Endocrine System • Thyroid Gland: > lower front part of the neck > thyroid hormones: regulate metabolism > bone growth and development of the brain and nervous system in children > maintain normal blood pressure, heart rate, digestion, muscle tone, and reproductive functions • Parathyroid Gland: > 2 pairs of small glands embedded in the surface of the thyroid gland > parathyroid hormone: regulating calcium levels • Adrenal Glands: > located on top of each kidney « corticosteroids » regulate the body’s metabolism, the balance of salt and water in the body, the immune system, and sexual function « produces hormones (eg, adrenaline) » help the body cope with physical and emotional stress by increasing the heart rate and blood pressure. 5 NOTES Endocrine System • Pancreas: > > > > toward the back of the abdomen behind the stomach digestive and hormonal functions digestive enzymes secretes hormones – insulin and glucagon regulate the level of glucose (sugar) in the blood Comparing Control Systems 6 NOTES Endocrine System Feedback Loops Negative feedback Causes activity to turn off until the right level is reached (detects too much of something) [hormone regulation] Positive feedback Causes an increase in activity until the right level is reached (detects too little of something) [contractions during child birth/ blood clotting] 7