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Transcript
Chapter 41: Endocrine System
Key Concepts
1. Hormones & how they work
2. Nervous & endocrine systems overlap
3. Major mammalian endocrine glands & hormones
Internal Communication
Systems of the Body
-Nervous system controls endocrine function; these
systems are cooperative
-nervous system = quick responses
-endocrine system = slower but longer acting responses
Endocrine System
Endocrine cells:
Target cells:
Hormones:
1. Circulating:
2. Paracrine:
3. Autocrine:
3 Hormone Types
• Peptides or polypeptides:
• Steroid hormones
• Amine hormones:
-
3 Hormone Types
Peptides
ADH, oxytocin, insulin
Water
soluble
Amines (derived from amino acids)
Thyroxine, epinephrine
(adrenaline)
Steroids
testosterone, estrogen,
progesterone
Lipid
soluble
Hormone receptors:
• Water-soluble hormones:
• Lipid soluble hormones:
How Hormones Function
Hormone Affects Are Diverse
Hypothalamus & Pituitary Gland
Hypothalamus:
-
Pituitary gland:
-
Hypothalamus & Pituitary Gland
Posterior Pituitary
Anterior Pituitary
Connection via
neurosecretory cells
Connection via portal
blood vessels
Fig. 41.7
Anterior pituitary secretes:
• Tropic hormones:
• Non-tropic hormones:
Ex. of Anterior Pituitary Gland
Tropic Hormones
(controls other endocrine glands)
Follicle stimulating hormone
-
Ex. of Anterior Pituitary Gland
Non-Tropic Hormones
(direct effects on target tissues)
Prolactin
Many functions
-
Anterior Pituitary Gland Hormone:
Human Growth Factor (GH)
*Tropic & Non-tropic effects
Wide variety of effects
Anterior pituitary also secretes thyrotropin (TSH)
(Tropic)
activates Thyroid Gland to produce thyroxine
Hormones Coordinate Other
Responses
1. Digestion
Hormones Coordinate Other
Responses
2. Blood Calcium
Hormones Coordinate Other
Responses
3. Blood glucose
Hormones Coordinate Responses to
External Environment Changes
1) Short-term stress (fight-or-flight):
2) Long-term stress:
Adrenal Gland: Stress
Pineal Gland: Biorhythms
Hormone receptor abundance can be regulated
How is the release of hormones controlled?
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