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Transcript
Human Immune Function
Evaluation Tools
The immune system is a key protection system against hazardous foreign substances. Proper functioning of the
immune system can be monitored by evaluating the antibody response to foreign antigens. However, immune
function is affected by a variety of exogenous environmental agents (e.g. infectious bacteria and virus), drugs (e.g.
immunosuppressants and immunomodulators), and intrinsic factors (e.g. stress, GI disorders and aging associated with
immuno-senescence). The consequence of lowered immune function may increase health risks such as susceptibility
to diseases causative pathogens.
To measure immune function, Chondrex provides antibody ELISA kits to determine IgA and IgG antibody levels to
various types of pathogenic and non-pathogenic environmental factors (Table 1). This series of ELISA kits employ the
ChonBlock® buffer system (ref paper), which eliminates non-specific reactions, as well as ionic interactions in indirect
ELISAs to provide accurate assay results. Chondrex also provides ChonBlock® buffer for in-house use for individual
assay purposes (Table 2). Please contact us for more information at [email protected].
Table 1 - Human Antibody Assay KitsPreve
Product
Antigen
Isotypes
Bacteria
Human Anti-E. coli Antibody Assay Kit
E. coli (O111:B4): Heat Killed
Lactobacillus casei: Heat Killed
Staphylococcus aureus: Heat Killed
IgA & IgG
Human Anti-LPS Antibody Assay Kit
LPS from E. coli (O-111:B4)
IgA & IgG
Human Anti-Pg-LPS Antibody Assay Kit
LPS from Porphyromonas gingivalis (Pg-LPS)
IgA & IgG
Human Anti-SEB Antibody Assay Kit
SEB from Staphylococcus aureus
IgA & IgG
Human Anti-PG-PS Antibody Assay Kit
Proteoglycan Polysaccharides (PG-PS) from
Streptococcus pyogenes
IgA & IgG
Human Anti-BSA Antibody Assay Kit
Bovine Albumin (BSA)
IgA & IgG
Human Anti-OVA Antibody Assay Kit
Ovalbumin (OVA)
IgA & IgG
Human Anti-BIgG Antibody Assay Kit
Bovine Immunoglobulin G (BIgG)
IgA & IgG
Human Anti-Lactobacillus Antibody Assay Kit
Human Anti-Staphylococcus Antibody Assay Kit
IgA & IgG
IgA & IgG
Bacterial Toxins & Cell Components
Dietary Proteins
Table 2 - ChonBlock® Buffer System
Product
Description
Blocking Buffer
Blocks hydrophobic binding of immunoglobulin to plastic surfaces
Sample/Standard Dilution Buffer
Blocks hydrophobic binding of immunoglobulin to plastic surfaces
No immunological and biological activity
No interference with target antibodies and antigens
Blocks hydrophobic and ionic binding of detection antibodies to plastic
Secondary Antibody Dilution Buffer and target antigen
Reduces edge effect
425.702.6365 or 888.246.6373 I www.chondrex.com I 1.0