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43 New Course Form For help filling out the form press F1 or look at the bottom of the screen. For additional instructions, see Course Form Instructions. New Course – Course not previously offered. Type of Action 1. Catalog Prefix and Number*: BTN 125 2. Course Title: Bioinformatics I Pilot Course Information: Are you requesting pilot status only at this time? Implementation Date? Yes No Are you requesting pilot status in addition to regular approval process? Yes Implementation date? Fall or Spring? Fall Year? 2013 Has this course been previously approved as pilot status 3. 4. Yes No No Justification for requested action. BTN 125 and BTN 126 are designed for individuals with some background in the life sciences who are preparing for employment in the emerging field of bioinformatics. Computational tools are used to store, retrieve, analyze or predict the composition or structure of biomolecules. Increasingly, the biotechnology workforce requires knowledge of bioinformatics, at least at the literacy level, in order to be able to communicate in the workplace. Submitting Entity: Curriculum Committee: Or College: BCTC 5. Person(s) Primarily Responsible for Proposal (Complete item only if course is not part of a curriculum package. Verify that members are still current and active prior to submission.): Name Teaching Area College Involvement of Others (Identify Individuals): 6. System Office Staff: 7. Others: 8. Is this course offered at other colleges? If yes, have they been involved in the development of this course? 9. Yes Yes Is this course duplicative or similar to other courses offered by KCTCS? No No N/A Yes If yes, Justification: A100 2012-2013 No 44 10. Credit / Contact Hours: 10a. Semester Credit Hours: Minimum 2 10b. Semester Contact Hours: 60 If lab, etc., ratio of contact hours to credit hours. (See contact/ credit hour ratio chart) 11. Grading Basis: Letter Grades 12. Repeat for additional credit: Pass/Fail Yes Maximum 2 30:1 Letter Grades/No GPA No If yes, complete the following: Total credit earned in course: Open Entry – Open Exit: 13. Total completions: Yes No 14a. Components (Check all components that require scheduling. For each component that is checked, enter the credit hours and contact hours for each component that is checked.): Component Credit Contact Component Credit Contact Hours Hours Hours Hours Lecture Laboratory Practicum 2 Co-Op 60 Clinical Discussion OR 14b. Integrated Components (If components are integrated, and only one component (lecture or lab) needs scheduling, rather than both lecture and lab, complete this section.) Lecture/ Lab 15. Lecture Credit Lecture Contact Lab Credit Lab Contact Requisites: Pre-requisite Yes No If yes, list: Co-requisite Yes No If yes, list: Pre-requisite or Co-requisite Yes No If yes, list: Completion of, or concurrent enrollment in BTN 201 and BTN 202. 16. A100 Implementation Term (Course scheduled to begin, ex. Fall 2012): Spring 2014 2012-2013 45 17. Proposed Course Description (Course description as it will appear in the catalog. Begin each statement with a verb.): Introduces the concepts and tools used in the application of information technology to the field of biology. Includes methods for data collection, storing and accessing biological data, fundamentals of sequence alignment, biological molecule structure prediction, and data mining and analysis. Course Proposal Rationale: 18. Will this course be a part of an approved curriculum/curricula? If yes, which curriculum/curricula? Yes No Biotechnology Laboratory Technician (Submit a New Curriculum or Revision Form) Course Competencies and Delivery: 19. Proposed Course Competencies/Student Outcomes (If part of an organized curriculum, how does it relate to program competencies /outcomes? Begin statement with a capital letter and end with a period.): Upon completion of this course, the student can: 1. 2. 3. 4. 5. 6. 7. 20. Determine protein coding regions and putative protein sequence(s) within a DNA sequence using existing bioinformatic databases. Perform searches of nucleotide and protein databases using a query sequence and retrieve sequences that are related to the query sequence. Align and compare multiple DNA or multiple protein sequences to predict functional domains. Apply bioinformatic methodology to test a scientific hypothesis. Locate consensus sequences, genes and open reading frames within biological sequences. Demonstrate basic knowledge of algorithms and their applications to bioinformatics. Construct a phylogenetic tree based on biological sequence data. Course Outline (Two-level outline required. Although courses may have more than two levels, the third level is not necessary.) I. II. III. A100 Introduction to Bioinformatics A. Historical and scientific context B. Types of problems studied with bioinformatics tools C. Types of databases. Working with single sequences A. Nucleotides a. Find ORFs, exons and introns b. Consensus sequences c. Assemble sequence fragments B. Amino Acids a. Primary structures b. Folding predictions c. Homologous regions Working with two or more sequences A. Nucleotides a. Homology b. BLASTn outputs B. Amino Acids a. 3-D structures 2012-2013 46 IV. V. VI. VII. b. Structural analogs c. BLASTp outputs Phylogenetics A. Phylogenetic relationships B. ClastalW alignments C. Construct phylogenetic trees RNA A. snRNP B. haplotypes C. BLASTr outputs Computing tools A. Organizing data B. Basic programming & algorithms Ethics of data deposits and extractions A. Social networking B. Data manipulation C. Benefits and risks 21. List of experiments/activities (Courses with components other than lecture. e.g., laboratory, clinical, practicum, etc., must include a sample list of experiment topics or activities. Does not have to be all -inclusive.): Use of algorithm to find greatest common divisor Finding a gene in a DNA sequence Comparing a given sequence across species Restriction enzyme analysis of DNA Sequence alignments and prediction of secondary structure 22. Indicate sample suggested classroom resources for course (Should not have publishing date greater than five years.) SUGGESTED LEARNING RESOURCES FOR THIS COURSE Lesk, AM. (2008) Introduction to Bioinformatics (3rd ed.) Oxford University Press. ISBN: 9780199208043 Clavere & Notredame (2008) Bioinformatics for Dummies (2nd ed.) For Dummies ISBN: 978-0470089859 22. Provide a rationale for using textbook/references older than five years. N/A 23. May this course be used as an equivalent for other courses? Yes If yes, please list. No X Signatures: Complete and submit a signature page for every proposal. *The System Office assigns new course numbers. Contact Mary Kleber at [email protected] A100 2012-2013