Download LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
B.Sc. DEGREE EXAMINATION – MATHS & PHYSICS
THIRD SEMESTER – APRIL 2014
AZ 3202 - BIOINFORMATICS - THEORY
Date : 10/04/2014
Time : 09:00-12:00
Answer ALL the questions
Dept. No.
Max. : 100 Marks
Part-A
(10×2=20 Marks)
1. What are the broad areas of Bioinformatics ?
2. How do you depict a palindrome sequence ?
3. Write the principle involved in microarray.
4. Write the application of Rasmol ?
5. Comment on AUTODOCK.
6. State BLAST algorithm.
7. Define homology modelling.
8. Distinguish alpha helix from beta pleat.
9. Mention any two network topology.
10.Expand: a) DDBJ c) PDB.
Answer any FOUR questions
Part-B
(4×10=40 Marks)
11. Enumerate the applications of Human Genome Project.
12.
13.
14.
15.
16.
Write about the multiple sequence alignment.
What are public domain data bases ? Write the data bases using respective tools.
How do you compile and run a C-program ?
What are the scope of Bioinformatics ?
Write the procedure to sequence DNA.
Part-C
Answer any TWO questions
(2×20=40 Marks)
17. Discuss the applications of Bioinformatics.
18. Elucidate the pharmacogenomic perspective of drug designing.
19. How to predict protein structures using proteomic tools ?
20. What are the tools being used in Genetic Engineering ?
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