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Anatomi Histology
Digestive System
Digestive
System
Histology
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General Structure and Functions
of the Digestive System
n
Organs of the Digestive System to:
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Ingest the food.
Transport the food.
Digest the food into smaller usable
components.
Absorb the necessary nutrients into the
bloodstream.
Expel the waste products from the body.
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Anatomi Histology
Digestive System
General Structure and Functions
of the Digestive System
n
Composed of two separate categories
of organs:
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digestive organs
accessory digestive organs.
Digestive organs collectively make up
the:
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gastrointestinal (GI) tract.
Also called:
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the digestive tract
alimentary canal.
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Anatomi Histology
Digestive System
General Structure and Functions
of the Digestive System
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The GI tract organs:
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continuous tube
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oral cavity
pharynx
esophagus
stomach
small intestine
large intestine
about 30 feet (9–10 meters)
from mouth to anus.
Smooth muscle in the wall
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responsible for motility
pushes materials from one end to the other.
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General Structure and Functions
of the Digestive System
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Accessory digestive organs:
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do not form the GI tube
can develop as outgrowths
are connected to the GI tract (some by ducts)
Assist the GI tract in the digestion of food.
Include:
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Teeth
Tongue
Salivary glands
Liver
Gallbladder
Pancreas
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Anatomi Histology
Digestive System
Digestive System Functions
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Ingestion
Digestion: break down of large particles of food
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Propulsion
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digestive enzymes
hormones
Absorption:
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peristalsis
segmentation
Secretion:
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mechanical digestion
chemical digestion
from external environment into internal environment
across mucosa
Elimination of wastes (defecation)
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Anatomi Histology
Digestive System
Oral Cavity (mouth)
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Entrance to the GI tract.
Initial site of digestion:
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mechanical digestion (via mastication)
chemical digestion (via enzymes in saliva).
Bounded anteriorly by the teeth and lips
Bounded posteriorly by the oropharynx.
Superior boundary is formed by the hard and
soft palates.
Floor, or inferior surface, of the oral cavity
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the tongue
the mylohyoid muscle covered with mucosa.
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Digestive System
Oral Cavity (mouth)
n
Two regions of the oral cavity
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The lateral walls are formed by the cheeks.
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Orbicularis oris muscle
Keratinized stratified squamous ET
Gingivae, or gums.
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Contain buccinator muscles
Lips (labia).
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Vestibule is the space between the cheeks or lips and the
gums.
Oral cavity proper.
Dense regular CT
Nonkeratinized ET
Labial frenulum.
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Digestive System
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Palate
n
Hard palate
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Soft palate
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Anterior two-thirds of the palate
hard and bony
Posterior one-third
soft and muscular
primarily composed of skeletal muscle.
Extending inferiorly from the posterior part of the
soft palate is the uvula.
When swallowing, the soft palate and the
uvula elevate to close off the opening of the
nasopharynx.
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Anatomi Histology
Digestive System
Palate
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n
Fauces represent the opening between
the oral cavity and the oropharynx.
Fauces are bounded by paired muscular
folds:
n glossopalatine arch (anterior fold)
n pharyngopalatine arch (posterior fold)
Palatine tonsils are housed between the
arches.
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Tongue
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An accessory digestive organ
Formed from:
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Manipulates and mixes ingested materials
during chewing
Forms the bolus.
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skeletal muscle
covered with lightly keratinized stratified
squamous epithelium.
a globular mass of partially digested material
Performs important functions in swallowing.
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Digestive System
Tongue
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Inferior surface of the tongue
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attaches to the floor of the oral cavity
By the lingual frenulum.
Numerous small projections (papillae)
cover the superior (dorsal) surface.
Posterior surface contains lingual
tonsils.
Skeletal muscles move the tongue.
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Salivary Glands
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Collectively produce and secrete saliva.
n a fluid that assists in the initial
activities of digestion
Volume of saliva secreted daily ranges
between 1.0 and 1.5 L.
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Most is produced during mealtime
Smaller amounts are produced
continuously to ensure that the oral cavity
remains moist.
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Digestive System
Salivary Glands
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Components of saliva
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Water: makes up 99%
Amylase: first step of chemical digestion
Lysozyme: antimicrobial
Functions
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Moisten food
Food molecules into solution: taste
Form bolus: for swallowing
Cleanse oral cavity.
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Salivary Glands
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Three pairs of large, multicellular
salivary glands:
n parotid glands
n submandibular glands
n sublingual glands
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Anatomi Histology
Digestive System
The Parotid Glands
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Largest salivary glands.
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located anterior and inferior to the ear
partially overlying the masseter muscle.
Produce about 25–30% of saliva
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conducted through the parotid duct to the
oral cavity.
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The Submandibular Glands
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Inferior to the body of the mandible.
Produce most of the saliva (about 60–
70%).
ducts opens through a papilla in the
floor of the mouth
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lateral to the the lingual frenulum.
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Digestive System
The Sublingual Glands
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Inferior to the tongue
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Each gland has multiple tiny sublingual ducts
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internal to the oral cavity mucosa.
open onto the inferior surface of the oral cavity
posterior to the submandibular duct papilla.
Contribute only about 3–5% of the total
saliva.
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Digestive System
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Teeth
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Collectively known as the dentition.
Responsible for mastication
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A tooth has:
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exposed crown
constricted neck
one or more roots
Roots of the teeth fit into dental alveoli
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first part of the mechanical digestion.
are sockets within the alveolar processes
on both the maxillae and the mandible.
Collectively, the roots, the dental alveoli, and the
periodontal ligament that binds the roots to the
alveolar processes form a gomphosis joint.
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Digestive System
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Digestive System
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Teeth
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Two sets of teeth
20 deciduous teeth, also called “milk teeth,” erupt between 6
months and 30 months after birth.
These teeth are eventually lost and replaced by 32 permanent
teeth.
The more anteriorly placed permanent teeth tend to appear
first, followed by the posteriorly placed teeth.
The last teeth to erupt are the third molars, often called
“wisdom teeth,” in the late teens or early 20’s.
Often the jaw lacks space to accommodate these final molars,
and they may either emerge only partially or grow at an angle
and become impacted.
Impacted teeth cannot erupt properly because of the angle of
their growth.
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Digestive System
Pharynx
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Review
Pharyngeal constrictors
Innervated by the vagus nerves
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General arrangement of
abdominal GI organs
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Peritoneum
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Parietal peritoneum
Visceral peritoneum
Peritoneal cavity
Intraperitoneal organs
Retroperitoneal organs
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Anatomi Histology
Digestive System
General arrangement of
abdominal GI organs
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Mesentaries
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Greater omentum
Lesser omentum
Mesentery proper
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Suspends small intestine from posterior wall of
abdomen
Mesocolon
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Double layered folds of peritoneum
Suspends large intestine
Peritoneal ligament
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Peritoneum that attaches one organ to another
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Digestive System
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Digestive System
General Histology of GI Organs
n
from the esophagus through the large
intestine
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a tube
composed of four concentric layers called tunics.
From deep to superficial, these tunics are:
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the mucosa
the submucosa
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the muscularis
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submucosal nerve plexus (Meissner plexus)
myenteric plexus (Auerbach plexus)
the adventitia or serosa
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Anatomi Histology
Digestive System
Esophagus
n
Tubular passageway
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Pharynx to stomach
Bolus
About 25 cm in adult
Esophageal hiatus: through diaphragm
Histology
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Mucosa: nonkeritinized stratified squamous ep.
Submucosa: thick, elastic fibers, mucous glands
Muscularis: inner circular, outer longitudinal
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Both skeletal and smooth
Adventitia
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Digestive System
Esophagus
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Superior esophageal sphincter:
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Skeletal muscle
Where pharynx and esophagus meet
Inferior esophageal sphincter
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Also cardiac sphincter
Circular smooth muscle
Orifice between esophagus and stomach
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Stomach
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General
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J-shaped
Functions
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Digestion
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Chemical
Mechanical
Results in chyme
Limited absorption
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Digestive System
Stomach
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Gross anatomy
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Cardia
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Cardiac orifice
Fundus
Body
Pylorus
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Pyloric sphincter
Pyloric orifice
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Greater curvature
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Lesser curvature
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Gastric folds (rugae)
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Greater omentum
Lesser omemtum
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Digestive System
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Stomach
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Histology
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Mucosa: simple columnar
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Gastric pits
Gastric glands
Muscularis
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3 layers
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Inner oblique
Middle circular
Outer longitudinal
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Digestive System
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Digestive System
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Small Intestine
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Finishes chemical digestion
Responsible for absorbing most of the nutrients.
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thin-walled tube
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Ingested nutrients spend at least 12 hours in the small
intestine.
about 6 meters (20 feet) in length.
coiled
Extends from the pylorus of the stomach to the
cecum of the large intestine
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occupies a significant portion of the abdominal cavity.
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Digestive System
Small Intestine
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The duodenum
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The jejunum
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first segment of the small intestine.
approximately 25 centimeters (10 inches) long
originates at the pyloric sphincter
major duodenal papilla
middle region of the small intestine.
approximately 2.5 meters (7.5 feet)
makes up approximately two-fifths of the small intestine’s total
length.
primary region for chemical digestion and nutrient absorption
The ileum
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is the last region of the small intestine.
about 3.6 meters (10.8 feet) in length
forms approximately three-fifths of the small intestine.
terminates at the ileocecal valve
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sphincter that controls the entry of materials into the large intestine.
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Digestive System
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Digestive System
Large Intestine
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approximate length of 1.5 meters (5 feet)
diameter of 6.5 centimeters (2.5 inches).
Absorbs most of the water and electrolytes from the remaining
digested material.
Watery material that first enters the large intestine soon
solidifies and becomes feces.
Stores fecal material until the body is ready to defecate.
Absorbs a very small percentage of nutrients still remaining in
the digested material.
Composed of four segments:
n the cecum, colon, rectum, anal canal
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Digestive System
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Digestive System
Accessory Digestive Organs
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The liver
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composed of four incompletely separated lobes
supported by two ligaments
Right lobe
Left lobe
Falciform ligament
Round ligament
Caudate lobe
Quadrate lobe
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Functions of The Liver
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Produce bile.
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a greenish fluid that breaks down fats into small droplets to
assist in their chemical digestion
Detoxify drugs, metabolites, and poisons.
Store excess nutrients and vitamins and release them
when they are needed.
Synthesize blood plasma proteins such as albumins,
globulins, and proteins required for blood clotting.
Phagocytize debris in the blood.
Help break down and recycle components of aged
erythrocytes and damaged or worn-out formed elements.
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Digestive System
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Digestive System
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Accessory Digestive Organs
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Gallbladder
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concentrates bile produced by the liver and stores this
concentrate until it is needed for digestion
cystic duct connects the gallbladder to the common bile duct
can hold approximately 40 to 60 milliliters of concentrated
bile
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Anatomi Histology
Digestive System
Accessory Digestive Organs
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Pancreas
n mixed gland because it exhibits both endocrine and exocrine
functions
Endocrine functions are performed by the pancreatic islets.
Exocrine activity results in the secretion of digestive enzymes,
collectively called pancreatic juice, into the duodenum.
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Digestive System
Accessory Digestive Organs
n
The biliary apparatus.
n network of thin ducts that carry bile from the liver and
gallbladder to the duodenum
n the left and right lobes of the liver drain bile into the left and
right hepatic ducts, respectively
n the left and right hepatic ducts merge to form a single
common hepatic duct
n the cystic duct attaches to the common hepatic duct and
carries bile to and from the gallbladder
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